Cost-utility of adjuvant zoledronic acid in patients with breast cancer and low estrogen levels [PDF]
, 2015 BACKGROUND: Adjuvant zoledronic acid (za) appears to improve disease-free survival (dfs) in women with early-stage breast cancer and low levels of estrogen (lle) because of induced or natural menopause.
Lamond, Nathan W D +3 more
core +1 more source
Regioselective ester cleavage during the preparation of bisphosphonate methacrylate monomers
Beilstein Journal of Organic Chemistry, 2011 New functional monomers bearing a methacrylate, a bisphosphonate function and, for most, an internal carboxylate group, were prepared for incorporation into copolymers with adhesive or anticorrosive properties.
Kamel Chougrani +3 more
doaj +1 more source
Bisphosphonate conjugation for bone specific drug targeting
Bone Reports, 2018 Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bone ...
Kristen B. Farrell +3 more
doaj +1 more source
Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
core +1 more source
The establishment of a bisphosphonate⁃related osteonecrosis of the jaw rat model
口腔疾病防治, 2017 With the wide use of bisphosphonates in bone diseases such as osteoporosis and bone metastases of ma⁃ lignant tumors, bisphosphonate⁃related osteonecrosis of the jaw has gained widely attention as a severe side effect. Ani⁃ mal model is a useful way to
LIU Jie, TANG Hua
doaj +1 more source
Patient level pooled analysis of 68,500 patients from seven major vitamin D fracture trials in the US and Europe [PDF]
, 2010 Objectives To identify participants’ characteristics that influence the anti-fracture efficacy of vitamin D or vitamin D plus calcium with respect to any fracture, hip fracture, and clinical vertebral fracture and to assess the influence of dosing ...
Abrahamsen, B +18 more
core +2 more sources
Comparison of osteoporosis pharmacotherapy fracture rates: Analysis of a marketScan® claims database cohort [PDF]
, 2018 Background: Several different classes of medications have been shown to be efficacious at preventing fractures in patients with osteoporosis. No study has compared real world efficacy at preventing fractures between all currently approved medications ...
Fox, Edward J. +5 more
core +2 more sources
Frontiers in Surgery, 2023 The risk of bisphosphonate (BP)-associated atypical femur fracture (AFF) has markedly increased over recent decades due to suppression of bone turnover, accumulation of structural micro-damage and reduction of bone remodeling consequent to long-term BP ...
Jianpeng Gao +9 more
doaj +1 more source
Knowledge and Performance of Dentists and Senior Dental Students Regarding the Treatment of Patients Taking Bisphosphonates in Bandar Abbas City, Iran [PDF]
Reviews in Clinical Medicine, 2021 Introduction: Bisphosphonates (BP) have recently been used in the treatment of bone diseases. The BP-related osteonecrosis of the jaw (BRONJ) is a severe complication of long-term usage of BP and can lead to serious consequences.
Arezoo Rayani +3 more
doaj +1 more source
Increasing the knowledge, identification and treatment of osteoporosis through education and shared decision-making with residents living in a retirement village community [PDF]
, 2018 Objective: This pilot study explored whether individual goal setting in a retirement village setting could improve strategies to strengthen bones in an ageing population and help prevent osteoporosis.
Australian Institute of Health and Welfare +25 more
core +2 more sources