Results 91 to 100 of about 52,862 (295)
Bisphosphonates: From Pharmacology to Treatment
, 2023 Bisphosphonates are among the most widely used drugs in the world for their many clinical indications. Their mechanism of action is based on the increase in the level of bone mineralization through the inhibition of osteoclastic activity and the ...
Ruggiero A., Mastrangelo S., Maurizi P.
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Bone Health and Aging in Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Klinefelter syndrome (KS) is typically diagnosed in young adults, but advances in prenatal testing have led to its recognition at a much earlier age. Conversely, diagnosis in late adulthood remains uncommon, but still occurs. Independently from the age at diagnosis, KS individuals now receive more accurate and tailored care management than in ...
Filippo Vignali +4 more
wiley +1 more source
Carpal Tunnel Syndrome Associated with Oral Bisphosphonates. A Population-Based Cohort Study.
PLoS ONE, 2016 BackgroundBisphosphonates are widely used to prevent osteoporotic fractures. Some severe musculoskeletal reactions have been described with this medication; among them, some cases of carpal tunnel syndrome.
Alfonso Carvajal +7 more
doaj +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2008 A osteonecrose induzida por bisfosfonatos é uma complicação que pode ocorrer em pacientes acometidos por doença osteolítica tais como mieloma múltiplo, portadores de metástases tumorais em tecido ósseo, osteoporose e que fizeram uso de droga do grupo dos
Paulo S. S. Santos +3 more
doaj +1 more source
, 2008 Bisphosphonates are potent inhibitors of osteoclast mediated bone resorption. These compounds are stable analogues of the inorganic pyrophosphate (PPi), which is an endogenous regulator of bone mineralization.
GUARNERI, VALENTINA
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Electrochemistry and Stability of 1,1′-Ferrocene-Bisphosphonates
Here, we investigate the electrochemical properties and stability of 1,1′-ferrocene-bisphosphonates in aqueous solutions. 31P NMR spectroscopy enables to track decomposition at extreme pH conditions revealing partial disintegration of the ferrocene core ...
Dominik Wickenhauser (14769766) +5 more
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency
Clinical Endocrinology, EarlyView.ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh +4 more
wiley +1 more source
Türk Osteoporoz Dergisi, 2010 Aim: The aim of this study was to evaluate the effects of bisphosphonates on new fracture development, bone mineral density and biochemical parameters in osteoporotic patients who were treated with these drugs for 5 years. Material and Methods: Thirty
Alev Çevikol +4 more
doaj
, 2008 Oliver Bock, Dieter FelsenbergCenter for Muscle and Bone Research, Campus Benjamin Franklin, Charité – University Medicine Berlin, Berlin, GermanyAbstract: Nitrogen-containing bisphosphonates are potent inhibitors of osteoclastic bone ...
Oliver Bock, Dieter Felsenberg
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