Results 81 to 90 of about 51,509 (201)
Adverse effects of bisphosphonates
, 2010 Use of bisphosphonates has been growing steadily in the last decade. This follows the introduction of simpler dosing regimes, the availability of lower-priced generics, and concerns about the safety of hormone-replacement therapy.
Abrahamsen, Bo, Abrahamsen, Bo; id_orcid
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Bisphosphonates: from preclinical evidence to survival data in the oncologic setting
Oncology Reviews, 2011 Bisphosphonate therapy has become a standard of therapy for patients with malignant bone disease. In vivo pre-clinical data suggest that bisphosphonates may exert an antitumor effect and preliminary clinical data show promising activity on metastatic ...
Daniele Santini +6 more
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, 2011 Allan LiptonMilton S. Hershey Medical Center, Pennsylvania State University, Hershey, PA, USAAbstract: Bisphosphonates inhibit osteoclast-mediated bone resorption, thereby inhibiting the release of growth factors necessary to promote cancer cell growth ...
Allan Lipton
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Oral bisphosphonates-associated osteonecrosis in rheumatoid arthritis [PDF]
, 2009 Adverse effects associated with the use of bisphosphonates are infrequent and consist of pyrexia, renal function impairment, and hypocalcemia. Bisphosphonates-associated osteonecrosis of the jaws is an uncommon but potentially serious complication of ...
Pelaz García, Alejandro +7 more
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Bisphosphonates use in children.
, 2012 Bisphosphonates are synthetic analogues of pyrophosphate that inhibit bone resorption by their action on osteoclasts. In recent years, bisphosphonates have been used in children for treatment of a growing number of disorders associated primarily with ...
Sebestyen, Judith F +2 more
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Bisphosphonates in multiple myeloma
, 2010 Background: Bisphosphonates are specific inhibitors of osteoclastic activity and are currently used as supportive therapy for multiple myeloma (MM). However, the exact clinical role of bisphosphonates in MM remains unclear. Objectives: This update of the
Miladinovic, B +15 more
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Bisphosphonates--mechanisms of action in multiple myeloma.
, 2000 Bisphosphonates are a class of anti-resorptive drugs, which are effective in the treatment of osteoclast-mediated bone disease, including the osteolytic bone disease. which is a major clinical feature of patients with multiple myeloma.
Van Camp, B +6 more
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Current perspectives on bisphosphonate treatment in Paget’s disease of bone
Therapeutics and Clinical Risk Management, 2014 Winnie Zee Man Wat Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong Abstract: Paget’s disease of bone is a chronic metabolic bone disease with focal increase in bone turnover.
Wat WZM
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, 2017 Carla Caffarelli,1 Andrea Montagnani,2 Ranuccio Nuti,1 Stefano Gonnelli1 1Department of Medicine, Surgery and Neuroscience, University of Siena, Italy; 2Division of Internal Medicine, General Hospital Misericordia, Grosseto, Italy Background ...
Montagnani A +3 more
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Biomedical applications of bisphosphonates.
, 2013 Since their discovery over 100 years ago, bisphosphonates have been used industrially as corrosion inhibitors and complexing agents. With the discovery of their pharmacological activity in the late 1960s, implicating their high affinity for ...
Giger EV, Castagner B, Leroux JC
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