Results 111 to 120 of about 82,508 (316)

Safety and Efficacy Assessment of Trastuzumab Emtansine in Indian Patients With Human Epidermal Growth Factor Receptor 2‐Positive Unresectable Locally Advanced or Metastatic Breast Cancer Previously Treated With Trastuzumab and a Taxane: An Open‐Label, Single‐Arm, Phase IV Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
A phase IV, single‐arm, open‐label, multicenter study assessing the safety and efficacy of trastuzumab emtansine in Indian patients for the treatment of human epidermal growth factor receptor 2 (HER2)‐positive unresectable locally advanced or metastatic breast cancer who received prior treatment with trastuzumab and a taxane.
Sudeep Gupta   +13 more
wiley   +1 more source

Comprehensive Approach to the Treatment and Prevention of Bisphosphonate-Induced Osteonecrosis of the Jaw

open access: yesJuvenis Scientia
Osteonecrosis of the jaws (ONJ) is a severe complication associated with the administration of bisphosphonates, drugs used for the treatment of osteoporosis and metastatic bone disease.
Pilipov, I.A.   +2 more
doaj   +1 more source

Bisfosfonatos: síntese, análises químicas e aplicações farmacológicas Bisphosphonates: synthesis, chemical analysis and pharmacological applications

open access: yesQuímica Nova, 2005
Bisphosphonates are drugs that have been widely used in different bone diseases, and have recently been used successfully against many parasites. Various synthetic routes to prepare different types of bisphosphonates have been described, with distinct ...
Christian Fernandes   +2 more
doaj   +1 more source

A Clinical Study of the Distribution and Morphology of Harris Lines

open access: yesArchaeometry, EarlyView.
ABSTRACT Harris lines are commonly used in bioarcheology to infer lifestyle in ancient populations; however, their etiology and identification parameters are still under debate. The aim of this study is to observe the distribution of the lesions in a contemporary clinical sample to address their association with etiological factors, age, biological sex,
Claudia Moro   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Bisphosphonates: from preclinical evidence to survival data in the oncologic setting

open access: yesOncology Reviews, 2011
Bisphosphonate therapy has become a standard of therapy for patients with malignant bone disease. In vivo pre-clinical data suggest that bisphosphonates may exert an antitumor effect and preliminary clinical data show promising activity on metastatic ...
Daniele Santini   +6 more
doaj   +2 more sources

Effect of bisphosphonate use on orthodontic tooth movement: A Systematic Review

open access: yesBrazilian Dental Science
Statement of problem: As bisphosphonates have an action mode which interferes in the osteo-resorptive process, their use during dental treatment may occasionally have side effects, such as: inhibition of tooth movement, delayed bone healing, and ...
Gurgiane Rodrigues Gurgel Lessa   +4 more
doaj   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh   +4 more
wiley   +1 more source

Knowledge of dental professionals and Dental students on bisphosphonates and bisphosphonate-associated osteonecrosis of the jaws

open access: diamond, 2022
Leonardo Paredes   +5 more
openalex   +2 more sources

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