Therapeutic potential of bixin on inflammation: a mini review [PDF]
Frontiers in Nutrition, 2023 Chronic inflammation is the underlying mechanism for many diseases. Thus, inflammatory signaling pathways are valuable targets for new treatment modalities.
Saminathan Shadisvaaran +3 more
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From Extraction to Stabilization: Employing a 22 Experimental Design in Developing Nutraceutical-Grade Bixin from Bixa orellana L. [PDF]
FoodsBixin is the main carotenoid found in the outer portion of the seeds of Bixa orellana L., commercially known as annatto. This compound is industrially employed in pharmaceutical, cosmetic, and food formulations as a natural dye to replace chemical ...
Christine L. Luna-Finkler +7 more
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Frontiers in Immunology, 2020 Multiple sclerosis (MS), an autoimmune and degenerative disease, is characterized by demyelination and chronic neuroinflammation. Bixin is a carotenoid isolated from the seeds of Bixa orellana that exhibits various potent pharmacological activities ...
Ying Xu
exaly +3 more sources
Deciphering the effects of bixin on pulmonary alveolar adenocarcinoma migration and proliferation via targeting BAX/BCL-2 and Cyclin D1 [PDF]
Scientific ReportsThere is a tremendous upsurge in lung cancer incidences due to changing lifestyles and other environmental risk factors. Unfortunately, the use of clinical therapeutics is causing serious side effects and drug-resistant tumors.
Ressin Varghese, Siva Ramamoorthy
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Bixin Combined with Metformin Ameliorates Insulin Resistance and Antioxidant Defenses in Obese Mice [PDF]
PharmaceuticalsBixin (C25H30O4; 394.51 g/mol) is the main apocarotenoid found in annatto seeds. It has a 25-carbon open chain structure with a methyl ester group and carboxylic acid.
Camila Graça Pinheiro +9 more
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Bixin, a New Atheroprotective Carotenoid Candidate, Prevents oxLDL-Induced Cytotoxicity and Mitochondrial Dysfunction in Macrophages: Involvement of the Nrf2 and NF-κB Pathways [PDF]
FoodsThe accumulation of oxidized low-density lipoprotein (oxLDL) and its toxicity in the arterial wall have been implicated in atherosclerosis. This study aimed to investigate the mechanisms underlying the atheroprotective effect of bixin, a carotenoid ...
Sabrina Somacal +4 more
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Validation, Measurement Uncertainty, and Determination of Bixin and Norbixin in Processed Foods of Animal Resources Distributed in Korea [PDF]
Food Science of Animal Resources, 2023 This research aimed to validate a high-performance liquid chromatography method for the quantitative determination of bixin and norbixin in various foods. The Diode Array Detector (495 nm) technique was used.
Ga-Yeong Lee +3 more
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Development of topical silver nano gel formulation of Bixin: Characterization, and evaluation of anticancer activity [PDF]
Saudi Pharmaceutical JournalObjective: Skin cancer refers to the pathological condition characterized by the proliferation of atypical skin cells in an uncontrolled manner. Plant-based products such as bixin although show promising anticancer properties, but maintaining their ...
Swapnil S. Patil +10 more
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Bixin Beyond Colour: Expanding Therapeutic Horizons Through the Integration of Pharmacological Potential with Modern Drug Design and Delivery Strategies [PDF]
Drug Design, Development and TherapyAhmed Raza Hashmi,1 Mahendran Sekar,1,2 Ling Shing Wong,3 BR Prashantha Kumar,4 Nur Najihah Izzati Mat Rani,2 Vinoth Kumarasamy5 1School of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia; 2Faculty of Pharmacy and Health Sciences ...
Hashmi AR +5 more
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One-step ultrasound-assisted recovery of yellow-orange-red natural coloring from defatted annatto seeds: A cleaner processing alternative [PDF]
Ultrasonics SonochemistryThe interest in natural colorants derived from sustainable processes has prompted research into obtaining bixin from defatted annatto (Bixa orellana L.) seeds.
Monique Martins Strieder +4 more
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