Multiple sclerosis (MS), an autoimmune and degenerative disease, is characterized by demyelination and chronic neuroinflammation. Bixin is a carotenoid isolated from the seeds of Bixa orellana that exhibits various potent pharmacological activities ...
Ye Yu +8 more
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Gene expression profile during seed development of Bixa orellana accessions varying in bixin pigment
Diverse morphological, cellular and physiological changes occur during seed maturation in Bixa orellana when the seed tissues form specialized cell glands that produce reddish latex with high bixin amounts.
Yair Cárdenas-Conejo +7 more
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ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF BIXIN PIGMENT FROM ANNATTO (Bixa orellana L.) SEEDS
Research on Bixa orellana L. have been done to isolate, identify and determine bixin percentage, the antioxidant and antibacterial activities of bixin from B. orellana seed.
Pipin T. Kurniawati +2 more
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Bixin Protects Against Kidney Interstitial Fibrosis Through Promoting STAT6 Degradation
Bixin, a natural carotenoid extracted from the seeds of Bixa orellana, has antioxidant and anti-inflammation effects. However, the pharmacological effects and underlying mechanisms of bixin in kidney interstitial fibrosis remain unknown.
Jianzhong Li +8 more
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Isolation and functional characterization of two dioxygenasese putatively involved in bixin biosynthesis in annatto (Bixa orellana L.) [PDF]
Carotenoid cleavage dioxygenases (CCDs) are enzymes that have been implicated in the biosynthesis of a wide diversity of secondary metabolites with important economic value, including bixin.
Victor Manuel Carballo-Uicab +8 more
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Characterization of bixin by LC‐MS and LC‐NMR [PDF]
AbstractAn overview upon modern analytical techniques for the isolation, separation, and structural identification of the essential bioactive carotenoid bixin is given. Isolation from biological matrices is performed by matrix solid phase dispersion (MSPD). The extract is separated with shape‐selective C30 columns.
Jens, Rehbein +8 more
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Bixinoids Derived from Bixa orellana as a Potential Zika Virus Inhibitor Using Molecular Simulations. Antiviral Effect on the Zika Virus of Bixinoids [PDF]
Zika fever is a viral infection of great relevance in public health, especially in tropic regions, in which there is a predominance of mosquitoes of the genus Aedes, vectors of the disease. Microcephaly in neonatal children and Guillain-Barré syndrome in
Antonio Carlos Nogueira Sobrinho +4 more
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Characterisation and stability evaluation of bixin nanocapsules
The aim of this study was to produce bixin nanocapsules by the interfacial deposition of preformed poly-ε-caprolactone (PCL). PCL (250 mg), capric/caprylic triglyceride (400 μL), sorbitan monostearate (95 mg) and bixin were dissolved in a mixture of acetone (60 mL) and ethanol (7.5 mL) under stirring (40 °C).
Lobato, Kleidson Brito de Sousa +5 more
openaire +2 more sources
STUDI METODE-METODE EKSTRAKSI PEWARNA MAKANAN ALAMI ANNATTO DARI BIJI KESUMBA (Bixa orellana)
Annatto is natural food colorant extracted from Bixa orellana seeds. The main constituent of annatto is bixin, a carotenoid having carboxylic acid groups at both ends of its molecular chain and one of these is methyl-esterified.
Johnner Parningotan Sitompul +2 more
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Protective effect of bixin on carbon tetrachloride-induced hepatotoxicity in rats
BACKGROUND: The liver is an important organ for its ability to transform xenobiotics, making the liver tissue a prime target for toxic substances. The carotenoid bixin present in annatto is an antioxidant that can protect cells and tissues against the ...
Priscila R Moreira +5 more
doaj +1 more source

