Results 71 to 80 of about 61,588 (194)

Organ Transplantation: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Prevalence of anti-BK polyomavirus IgG in A Sample of Iraqi renal transplant recipients

open access: yesDiyala Journal of Medicine, 2022
Background: BK virus, a human polyomavirus, causes nephropathy and allograft loss in renal transplant recipients. Although it was discovered in 1971, understanding of the humoral immune response to BKV is limited.
Ghufran Hammoodi Abed ,   +5 more
doaj   +1 more source

Targeting the Glial Scar: Biomaterial and Drug‐Based Strategies for Modulation In Vitro

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 12, December 2025.
Human cell‐based in vitro glial‐scar model used to evaluate therapeutics and biomaterials. ABSTRACT Glial scarring creates a significant obstacle for axonal regeneration in the central nervous system after injury and represents one of the main hurdles for neural microelectrode development.
Luise Schlotterose   +8 more
wiley   +1 more source

A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses

open access: yeseLife, 2020
In pursuit of therapeutics for human polyomaviruses, we identified a peptide derived from the BK polyomavirus (BKV) minor structural proteins VP2/3 that is a potent inhibitor of BKV infection with no observable cellular toxicity.
Joshua R Kane   +12 more
doaj   +1 more source

BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy

open access: yesiScience, 2020
Summary Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients.
Julia Manzetti   +8 more
semanticscholar   +1 more source

Hemorrhagic Cystitis Following Hematopoietic Stem Cell Transplantation in Children: A Single Pediatric Center Experience

open access: yesPediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Hemorrhagic cystitis (HC) is a frequent and potentially severe complication following hematopoietic stem cell transplantation (HSCT) in children. It significantly affects the quality of life and prolongs hospitalization. Despite its frequency, no standardized management guidelines exist.
Pauline Mazilier   +8 more
wiley   +1 more source

BK polyomavirus association with colorectal cancer development

open access: yesGenetics and Molecular Research, 2016
The development of human neoplasms can be provoked by exposure to one of several viruses. Burkitt lymphoma, cervical carcinoma, and hepatocellular carcinoma are associated with Epstein-Barr, human papilloma, and hepatitis B virus infections, respectively.
M N, Khabaz   +6 more
openaire   +2 more sources

Salivary and Serum Cytokine Concentrations in Kidney Transplantation: A Prospective Study

open access: yesOral Diseases, Volume 31, Issue 12, Page 3474-3481, December 2025.
ABSTRACT Background Kidney transplant recipients (KTRs) experience immune modulation, which may lead to graft rejection and other adverse outcomes. Although serum cytokines are well‐established systemic immune markers, the role of salivary biomarkers has never been reported in the literature.
Luciano Miziara   +10 more
wiley   +1 more source

Proteinuria After Kidney Transplantation

open access: yesPediatric Transplantation, Volume 29, Issue 8, December 2025.
ABSTRACT Proteinuria is a relatively frequent complication in both adults and children after kidney transplantation (40%–80%). It is usually mild and predominantly of tubular origin and is caused mainly by rejection, mTOR inhibitors, or hypertension; however, proteinuria could also be in the nephrotic range and of glomerular origin if caused by the ...
Tomas Seeman   +6 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

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