Results 81 to 90 of about 61,588 (194)

Trained Immunity in Health and Disease

MedComm, Volume 6, Issue 11, November 2025.
Growth and timescale of medical publications on trained immunity and its related health and disease. This figure illustrates the number of published papers over time, from 2000 to 2025 (by August 14, 2025), related to trained immunity and its related health and disease.
Meng Yao, Jian Zhou, Jialun Mei, Chuan Gao, Peng Ding, Gan Li, Changqing Zhang, Zhiwei Li, Junjie Gao   +8 more
wiley   +1 more source

BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies

Clinical Microbiology Reviews, 2017
SUMMARY BK polyomavirus (BKV) causes frequent infections during childhood and establishes persistent infections within renal tubular cells and the uroepithelium, with minimal clinical implications.
George R. Ambalathingal, R. Francis, M. Smyth, Corey Smith, R. Khanna   +4 more
semanticscholar   +1 more source

Longitudinal assessment of the CXCL10 blood and urine concentration in kidney transplant recipients with BK polyomavirus replication—a retrospective study

Transplant International, 2020
In kidney transplant recipients (KTRs), BK polyomavirus (BKPyV) replication may progress to polyomavirus‐associated nephropathy (PVAN). In this retrospective study, we assessed the chemokine CXCL10 in urine and blood samples consecutively acquired from ...
L. Weseslindtner, L. Hedman, Yilin Wang, R. Strassl, I. Helanterä, S. Aberle, G. Bond, K. Hedman   +7 more
semanticscholar   +1 more source

Exposing the Molecular Machinery of BK Polyomavirus [PDF]

Structure, 2016
BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting ...
openaire   +2 more sources

Polyomavirus BK Neutralizing Activity in Human Immunoglobulin Preparations [PDF]

Transplantation, 2010
Polyomavirus BK (BKV) infection can cause nephropathy in the allograft kidney. No well-established drug treatment is available at this time. Human intravenous immunoglobulins (IVIG) have been used as an empiric therapy without proof of effectiveness.We tested five lots of commercially available IVIG preparations from two different suppliers for ...
Parmjeet S, Randhawa, Kristine, Schonder, Ron, Shapiro, Nousha, Farasati, Yuchen, Huang   +4 more
openaire   +2 more sources

Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Setsuko Shioda, Fumio Kasai, Midori Ozawa, Azusa Ohtani, Masashi Iemura, Ken Watanabe, Arihiro Kohara   +6 more
wiley   +1 more source

BK Polyomavirus and the Transplanted Kidney [PDF]

Transplantation, 2016
BK polyomavirus is ubiquitous, with a seropositivity rate of over 75% in the adult population. Primary infection is thought to occur in the respiratory tract, but asymptomatic BK virus latency is established in the urothelium. In immunocompromised host, the virus can reactivate but rarely compromises kidney function except in renal grafts, where it ...
Lamarche, Caroline, Orio, Julie, Collette, Suzon, Senécal, Lynne, Hébert, Marie-Josée, Renoult, Édith, Tibbles, Lee Anne, Delisle, Jean-Sébastien   +7 more
openaire   +2 more sources

Reduced incidence of relapse after checkpoint inhibitors relative to brentuximab vedotin as salvage therapy before allogeneic stem cell transplantation for refractory/relapsed Hodgkin lymphoma: A retrospective analysis

British Journal of Haematology, Volume 207, Issue 4, Page 1684-1689, October 2025.
Eighty‐two patients were eligible for allogeneic transplantation (Allo‐SCT) at our Institution between April 2014 and August 2022. Of these, 72 actually received Allo‐SCT, n = 44 after checkpoint inhibitor (CPI) containing salvage therapy (CPI cohort) and n = 28 with brentuximab‐vedotin (BV) containing therapy without CPI (BV cohort).
Jacopo Mariotti, Chiara Pinton, Laura Giordano, Daniela Taurino, Barbara Sarina, Chiara De Philippis, Daniele Mannina, Cristina Tentori, Armando Santoro, Stefania Bramanti   +9 more
wiley   +1 more source

BK Virus Nephropathy: Prevalence, Impact and Management Strategies

International Journal of Nephrology and Renovascular Disease, 2020
Rajeev Sharma,1,2 Mareena Zachariah3 1School of Medicine, University of Nevada Las Vegas, Las Vegas, NV, USA; 2Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA; 3Department of Nephrology, Wayne State University ...
Sharma R, Zachariah M
doaj  

BK polyomavirus infection promotes growth and aggressiveness in bladder cancer

Virology Journal, 2020
Background Recent studies have confirmed the integration of the BK polyomavirus (BKPyV) gene into the cellular genome of urothelial carcinomas in transplant recipients, further confirming the correlation between BKPyV and urothelial carcinomas after ...
Yigang Zeng, Jiajia Sun, Juan Bao, T. Zhu   +3 more
semanticscholar   +1 more source