Results 261 to 270 of about 1,962,745 (339)

Conkazal‐M1 from the MKAVA family of conotoxins: A dual‐function protease inhibitor and neuroactive peptide

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Matías Leonel Giglio, Samuel S. Espino, Zildjian G. Acyatan, Maren Watkins, Baldomero M. Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +12 more
wiley   +1 more source

Composition of the neutralising antibody response predicts risk of BK virus DNAaemia in recipients of kidney transplants. [PDF]

EBioMedicine
Chong SMY, Hung RKY, Yuen Chang F, Atkinson C, Fernando R, Harber M, Magee CN, Salama AD, Reeves M.   +8 more
europepmc   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

Protein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska, Marta Orlikowska, Maciej Nielipiński, Bartosz Sekuła, Katarzyna M. Błażewska, Edyta Gendaszewska‐Darmach, Agnieszka J. Pietrzyk‐Brzezińska   +6 more
wiley   +1 more source

Nanopore Electroporation: A New Delivery Method Within the Field of Epigenetic Editing

Small, Volume 22, Issue 28, 18 May 2026.
Nanopore‐mediated electroporation was used to deliver a CRISPRi system to clonal β‐cells. This enabled targeted downregulation of insulin expression while maintaining high cell viability. ABSTRACT Epigenetic modifications influence gene expression and contribute to type 2 diabetes (T2D), but establishing causality requires targeted modulation of ...
Frida Ekstrand, Sabrina Ruhrmann, Karl Bacos, Sabine Bartel, Pytrick Jellema, Marianne G. Rots, Charlotte Ling, Christelle N. Prinz   +7 more
wiley   +1 more source

Combined Impact of Prior Polatuzumab Vedotin Plus Bendamustine and Rituximab Therapy and Myeloablative Conditioning on Early Post-Transplant BK Virus-Associated Hemorrhagic Cystitis. [PDF]

J Hematol
Hayashi Y, Tsukada M, Shinoda D, Matsui M, Iwama K, Kajiwara K, Kozai Y.   +6 more
europepmc   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source

Characterization of <i>Herpesviridae</i> Family Members, BK Virus, and Adenovirus in Children and Adolescents with Nephrotic Syndrome. [PDF]

Viruses
Ferreira Menoni SM, Leon LL, de Lima RG, Lutaif ACGB, Prates LC, Palma LMP, Costa SCB, Belangero VMS, Bonon SHA.   +8 more
europepmc   +1 more source

First Serological Evidence of Avian Metapneumovirus and Infectious Laryngotracheitis Virus in Commercial Poultry in the Ashanti Region of Ghana

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study reports the first serological evidence of avian metapneumovirus and infectious laryngotracheitis virus in commercial poultry in Ghana. High aMPV seroprevalence (49%) and lower ILTV prevalence (7%) were detected, with some coinfection.
Patrick Mensah Amponsah, Kwadwo Boampong, Augustina Angelina Sylverken   +2 more
wiley   +1 more source

Post‐mortem CT detection of fatal air embolism after aerosolized fibrin glue for bladder bleeding

Journal of Forensic Sciences, Volume 71, Issue 3, Page 1507-1512, May 2026.
Abstract Radiation‐induced hemorrhagic cystitis (RHC) is a severe complication of pelvic radiotherapy, often used to treat various pelvic malignancies. Despite multiple therapeutic options, including conservative and invasive interventions, the optimal management remains uncertain. We report the case of a 76‐year‐old male with pulmonary emphysema and a
Beatrice Benedetti, Nazario Foschi, Caterina Pesaresi, Tommaso Tartaglione, Matteo Mancino, Alberto Chighine, Fabio De‐Giorgio   +6 more
wiley   +1 more source

Performance evaluation of the high-throughput quantitative Alinity m BK virus assay. [PDF]

J Clin Microbiol
Hirschhorn JW, Sasaki MM, Kegl A, Akter T, Dickerson T, Narlieva M, Nhan N, Liu T, Jim P, Young S, Orner E, Thwe P, Lucic D, Goldstein DY.   +13 more
europepmc   +1 more source