Results 271 to 280 of about 1,962,745 (339)

Telomere Dysfunction and Proteostasis Decline Define Distinct Pathways of Cellular Senescence in the Human Respiratory Tract

Aging Cell, Volume 25, Issue 5, May 2026.
Telomere shortening occurs with age in the respiratory epithelium, but telomere dysfunction‐induced foci (TIF) accumulate only late in life. In contrast, proteostasis decline emerges earlier and correlates with functional impairment, suggesting it may be a primary driver of cellular senescence during physiological aging.
Céline Coquette, Kamar Bouchoucha, Manon Mahieu, Stijn E. Verleden, Axelle Loriot, Kevin Norris, Duncan M. Baird, Amélie Derumier, Delphine Hoton, Laurens De Sadeleer, Arno Vanstapel, Bart M. Vanaudenaerde, Maëlle de Ville de Goyet, Bénédicte Brichard, Antoine Froidure, Wim Wuyts, Jan Van Slambrouck, Laurens J. Ceulemans, William Trigaux, Caroline Huart, Anabelle Decottignies   +20 more
wiley   +1 more source

Shedding Light on Viral Shedding: Novel Insights into Nuclear Assembly, Cytoplasmic Transformation and Extracellular Vesicle Release of the BK Virus. [PDF]

Int J Mol Sci
Gerges D, Abd El-Ghany K, Hevesi Z, Aiad M, Omic H, Baumgartner C, Winnicki W, Eder M, Schmidt A, Eskandary F, Wagner L.   +10 more
europepmc   +1 more source

A cost–benefit analysis of the implementation and scale‐up of harm reduction interventions in the Australian Capital Territory

Addiction, Volume 121, Issue 5, Page 1272-1289, May 2026.
Abstract Background and aims Harm reduction interventions aim to reduce negative consequences of drug use. We aimed to estimate the cost, health impact and economic benefits of current, expanded and new harm reduction interventions for people who use drugs in the Australian Capital Territory.
Anna L. Bowring, Tom Tidhar, Anna Olsen, Christopher Bailie, Kelvin Burke, Rowan Martin‐Hughes, Helen Keane, Paul Dietze, Nick Scott   +8 more
wiley   +1 more source

[BK virus nephropathy after allogeneic hematopoietic stem cell transplantation: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang WL, Zu YL, Huang ZH, Li Z, Gui RR, Wang J, Wang XJ, Wang HL, Fan XX, Song YP, Fang BJ, Zhou J.   +11 more
europepmc   +1 more source

Novel Approaches for Investigating Host Responses to HIV Infection in Ex Vivo Human Genital Tissues

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Understanding local immune responses and the structural integrity of the genital mucosal barrier is essential for advancing knowledge of both susceptibility to sexual HIV transmission and the pathogenesis of chronic HIV infection. This review highlights innovative methodologies for investigating host responses to HIV infection using ex vivo ...
Mathias Franzén Boger, Vilde Kaldhusdal, Kristina Broliden   +2 more
wiley   +1 more source

AIDS-Associated BK Virus Nephropathy in Native Kidneys: A Case Report and Review of the Literature. [PDF]

J Investig Med High Impact Case Rep
Ebrahimi N, Al Baghdadi M, Zuppan CW, Rogstad DK, Abdipour A.   +4 more
europepmc   +1 more source

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Polyoma BK Virus in Kidney Transplant Recipients: Screening, Monitoring, and Management

Transplantation, 2021
Polyomavirus BK virus (BKPyV) infection is an important complication of kidney transplantation and allograft failure. The prevalence of viremia is 10%–15%, compared with BK-associated nephropathy (BKPyVAN) at 3%–5%.
T. Myint, Chanel H Chong, Melanie Wyld, B. Nankivell, K. Kable, G. Wong   +5 more
semanticscholar   +1 more source