Results 101 to 110 of about 2,195 (192)

Transferrin Saturation Can Serve as a Novel Biomarker for Predicting the Occurrence and Development of BK Virus‐Related Nephropathy After Kidney Transplantation

Journal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT BK polyomavirus reactivation is a common complication after kidney transplantation, affecting the long‐term survival of the transplanted kidney. However, it is unclear whether iron levels affect BKPyV reactivation after kidney transplantation.
Yongchuang Yan, Zhigang Wang, Yonghua Feng, Yang Qiu, Yuanbo Qi, Fumin Cheng, Yi Feng, Di Zhang, Guiwen Feng, Wenjun Shang   +9 more
wiley   +1 more source

Association of Posttransplant Circulating 25‐Hydroxyvitamin D and Late‐Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD)

Transplant Infectious Disease, Volume 27, Issue 2, March/April 2025.
Lower posttransplant circulating 25(OH)D level is significantly associated with a higher incidence of late‐onset infection among kidney transplant recipients, especially urinary tract infections in male recipients. ABSTRACT Introduction Late‐onset infection occurring more than 6 months after transplantation is a major threat to the long‐term survival ...
Zhongyu Yuan, Michal L. Melamed, Sandesh Parajuli, Didier Mandelbrot, Brad C. Astor   +4 more
wiley   +1 more source

Reactivation of BK Polyomavirus in Urine Cytology Is Not Associated with Urothelial Cell Carcinoma

Viruses, 2020
BK polyomavirus (BKPyV) has been associated with some high-grade and special urothelial cell carcinoma (UCC) subtypes in immunosuppressed patients. Here, we evaluated the relationship of BKPyV-positive urine cytology specimens (UCS) with UCC.
Faisal Klufah, Ghalib Mobaraki, Axel zur Hausen, Iryna V. Samarska   +3 more
doaj   +1 more source

Multiple DNA Viruses and HPV Integration in Inverted Papilloma and Associated Sinonasal Carcinoma

The Laryngoscope, Volume 135, Issue 2, Page 677-686, February 2025.
HPV6 integration was observed in benign inverted papilloma, whereas HPV16 is present pre‐ and post‐malignant transformation. Marked increase in viral diversity was present, supported by accumulation of mutations over time. Objectives Sinonasal inverted papilloma (IP) has a locally destructive growth pattern, can relapse, and can undergo malignant ...
Maria K. Jauhiainen, Lari Pyöriä, Sanna Viitasalo, Ushanandini Mohanraj, Leena‐Maija Aaltonen, Maria Söderlund‐Venermo, Jaana Hagström, Antti A. Mäkitie, Maria F. Perdomo, Saku T. Sinkkonen   +9 more
wiley   +1 more source

Temporal Proteomic Analysis of BK Polyomavirus Infection Reveals Virus-Induced G2 Arrest and Highly Effective Evasion of Innate Immune Sensing. [PDF]

, 2019
BK polyomavirus (BKPyV) is a small DNA virus that establishes a life-long persistent infection in the urinary tract of most people. BKPyV is known to cause severe morbidity in renal transplant recipients and can lead to graft rejection.
Antrobus, Robin, Caller, Laura G, Crump, Colin M, Davies, Colin TR, Lehner, Paul J, Weekes, Michael P   +5 more
core   +1 more source

Cellular Immunity Against BK Polyomavirus in Kidney Transplant Recipients: A Comprehensive Review

Transplant Infectious Disease, Volume 27, Issue 1, January/February 2025.
ABSTRACT BK polyomavirus (BKPyV) is an important opportunistic viral infection that complicates kidney transplantation. Uncontrolled viral replication may result in BKPyV‐associated nephropathy (BKPyVAN), a major cause of premature allograft damage and failure.
Mohammed Al‐Talib, Anna Skaria, Siân Griffin   +2 more
wiley   +1 more source

Pre-transplant immune factors may be associated with BK polyomavirus reactivation in kidney transplant recipients.

PLoS ONE, 2017
BK polyomavirus (BKPyV) reactivation in kidney transplant recipients can lead to allograft damage and loss. The elements of the adaptive immune system that are permissive of reactivation and responsible for viral control remain incompletely described. We
David DeWolfe, Jinal Gandhi, Matthew R Mackenzie, Thomas A Broge, Evelyn Bord, Amaara Babwah, Didier A Mandelbrot, Martha Pavlakis, Francesca Cardarelli, Raphael Viscidi, Anil Chandraker, Chen S Tan   +11 more
doaj   +1 more source

Specific Detection of Serum Antibodies against BKPyV, A Small DNA Tumour Virus, in Patients Affected by Choroidal Nevi

Frontiers in Microbiology, 2017
Ocular or choroidal nevus (CN) is a rare benign neoplastic lesion of the eye. The cause of CN onset/progression, which arises from the transformation of ocular melanocytes, is not known. A fraction of CN patients may develop uveal melanoma. The objective
Silvia Pietrobon, Ilaria Bononi, Francesca Lotito, Paolo Perri, Sara Violanti, Elisa Mazzoni, Fernanda Martini, Mauro G. Tognon   +7 more
doaj   +1 more source

BK virus salivary shedding and viremia in renal transplant recipients [PDF]

, 2019
Objectives: This study aimed to verify the presence of polyomavirus BK (BKPyV) in the saliva of kidney transplant recipients and to correlate it with blood viremia.
Agena, Fabiana, Braz-Silva, Paulo Henrique, Canto, Cynthia Motta do, David-Neto, Elias, Fink, Maria Cristina Domingues, Gallottini, Marina, Galvão, Gustavo Souza, Palmieri, Michelle, Pannuti, Claudio Sergio, Pierrotti, Ligia Camera, Sarmento, Dmitry José de Santana, Tozetto-Mendoza, Tânia Regina   +11 more
core   +3 more sources

Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection.

PLoS Pathogens
BK polyomavirus (BKPyV) is a major cause of kidney transplant failure, for which there are no antivirals. The current model is that BKPyV expresses TAg (large T antigen) early during infection, promoting cells to enter S phase where the viral DNA can ...
Jason M Needham, Sarah E Perritt, Sunnie R Thompson   +2 more
doaj   +1 more source