Results 101 to 110 of about 1,873 (184)

B-series gangliosides are receptors for BKPyV.

, 2013
(A) Schematic representation of structures of disialic acid-containing b-series gangliosides GD3, GD2, GD1b, GT1b and of the monosialylated a-series ganglioside GM1 indicating the abbreviated designations used here for individual residues in the ...
Bärbel S. Blaum (114952), Luisa J. Ströh (469044), Ten Feizi (114959), Ursula Neu (147265), Thomas Peters (147287), Walter J. Atwood (469045), Yan Liu (25061), Angelina S. Palma (201621), Stacy-ann A. Allen (469043), Martin Frank (5582), Thilo Stehle (114963)   +10 more
core   +1 more source

SGTA knockdown perturbs SV40 and BKPyV infection.

, 2014
(A) CV-1 cells were transfected with scrambled or siRNAs targeting SGTA for 36 h before being harvested and analyzed by immunoblotting with the indicated antibodies.
Madhu Sudhan Ravindran (543852), Billy Tsai (221410), Christopher Paul Walczak (543851), Takamasa Inoue (221408)   +3 more
core   +1 more source

Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection.

PLoS Pathogens
BK polyomavirus (BKPyV) is a major cause of kidney transplant failure, for which there are no antivirals. The current model is that BKPyV expresses TAg (large T antigen) early during infection, promoting cells to enter S phase where the viral DNA can ...
Jason M Needham, Sarah E Perritt, Sunnie R Thompson   +2 more
doaj   +1 more source

Structure of a BKPyV VP1-GD3 oligosaccharide complex.

, 2013
(A) Structure of BKPyV VP1 pentamer in complex with GD3 oligosaccharide. One VP1 monomer is highlighted in green. Monosaccharides unbiased by crystal contacts are colored orange, while the ones binding to crystal contacts are colored white. (B) Composite
Bärbel S. Blaum (114952), Luisa J. Ströh (469044), Ten Feizi (114959), Ursula Neu (147265), Thomas Peters (147287), Walter J. Atwood (469045), Yan Liu (25061), Angelina S. Palma (201621), Stacy-ann A. Allen (469043), Martin Frank (5582), Thilo Stehle (114963)   +10 more
core   +1 more source

BK polyomavirus in Kidney transplant recipients: screening, monitoring and clinical management

Brazilian Journal of Nephrology, 2014
BK polyomavirus (BKPyV) is a causal agent of nephropathy, ureteral stenosis and hemorrhagic cystitis in kidney transplant recipients, and is considered an important emerging disease in transplantation.
Rafael Brandão Varella, Jorge Reis Almeida, Patrícia de Fátima Lopes, Jorge Paulo Strogoff de Matos, Paulo Menezes, Jocemir Ronaldo Lugon   +5 more
doaj   +1 more source

Role of a nuclear localization signal on the minor capsid Proteins VP2 and VP3 in BKPyV nuclear entry

Virology, 2015
BK Polyomavirus (BKPyV) is a ubiquitous nonenveloped human virus that can cause severe disease in immunocompromised populations. After internalization into renal proximal tubule epithelial cells, BKPyV traffics through the ER and enters the cytosol. However, it is unclear how the virus enters the nucleus.
Bennett, Shauna M., Zhao, Linbo, Bosard, Catherine, Imperiale, Michael J.   +3 more
openaire   +2 more sources

L'impact de la sérologie pré-greffe sur le risque re réactivation du BKPyV après une transplantation rénale

, 2020
Contexte: La néphropathie associée au virus polyomavirus BK (BKPyVAN) est une maladie incommodante observée chez les receveurs de greffe rénale immunodéprimés suite à une réactivation du polyomavirus BK (BKPyVV).
Dakroub, Fatima El Zahraa
core  

Characterizing determinants of BK Polyomavirus-specific immune response [PDF]

, 2016
BK polyomavirus (BKPyV) is one of now 13 human polyomavirus (HPyV) species detected in humans. BKPyV is only known to infect humans and seroprevalence rates of more than 90% have been reported in adult populations around the world.
Cioni, Michela
core   +1 more source

BK Polyomavirus (BKPyV)-specific CD8 T-cell expansion in vitro using 27mer peptide antigens for developing adoptive T-cell transfer and vaccination.

, 2020
BACKGROUND BK polyomavirus (BKPyV) remains a significant cause of premature kidney transplant failure. In the absence of effective antivirals, current treatments rely on reducing immunosuppression to regain immune control over BKPyV replication ...
Wernli M, Hirsch HH, Wilhelm M, Kaur A
core   +1 more source

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells.

PLoS Pathogens
BK polyomavirus (BKPyV) is a ubiquitous human virus that establishes a persistent infection in renal tubular epithelial cells and mainly causes disease in kidney transplant recipients.
Elias Myrvoll Lorentzen, Stian Henriksen, Christine Hanssen Rinaldo   +2 more
doaj   +1 more source