Results 151 to 160 of about 1,873 (184)

Genotypes and Variants of BKPyV in Organ Donors after Brain Death

open access: yesInternational Journal of Molecular Sciences, 2022
Kidney transplantation from a donor with latent BKPyV might be the cause of serious complications, such as BK virus-associated nephropathy. The aim of the study was to determine the prevalence of BKPyV infection in donors after brain death (DBDs), to analyse the molecular variation of BKPyV and to compare clinical and inflammation parameters of DBDs ...
Andrzej Jakubczak   +2 more
exaly   +5 more sources

Discriminating between JCPyV and BKPyV in Urinary Virome Data Sets [PDF]

open access: yesViruses, 2021
Polyomaviruses are abundant in the human body. The polyomaviruses JC virus (JCPyV) and BK virus (BKPyV) are common viruses in the human urinary tract. Prior studies have estimated that JCPyV infects between 20 and 80% of adults and that BKPyV infects between 65 and 90% of individuals by age 10.
Catherine Putonti   +2 more
exaly   +7 more sources

Longitudinal monitoring of BKPyV miRNA levels in kidney transplant recipients with BKPyV-related pathology reflects viral DNA levels and remain high in viremia patients after clearance of viral DNA [PDF]

open access: yesTransplant Infectious Disease, 2022
AbstractIntroductionIt is unclear whether polyomavirus BK (BKPyV) microribonucleic acid (miRNA) measurement has additional diagnostic and predictive value in kidney transplant recipients (KTR) as compared to current methods of monitoring BKPyV DNA loads.Patients and methodsA retrospective, longitudinal study was performed in 30 KTR with BKPyV viruria ...
Lilli Gard   +2 more
exaly   +6 more sources

Characteristics of polyomavirus BK (BKPyV) infection in primary human urothelial cells [PDF]

open access: yesVirology, 2013
High-level polyomavirus BK (BKPyV) replication in urothelial cells is a hallmark of polyomavirus-associated hemorrhagic cystitis (PyVHC), a painful condition affecting bone marrow transplant recipients. In kidney transplant recipients, replication in tubular epithelial cells is associated with overt disease whereas high-level urothelial replication is ...
Stig Linder   +2 more
exaly   +5 more sources

BKPyV causing meningoencephalitis in HIV/AIDS patients in Argentina

open access: yesDiagnostic Microbiology and Infectious Disease
Opportunistic infections in the central nervous system (CNS) by JCPyV/BKPyV in HIV/AIDS patients increase morbidity/mortality, especially in low-income countries. In Argentina, data regarding CNS-infection by polyomavirus in HIV/AIDS are scarce. We retrospectively evaluated BKPyV/JCPyV infections in cerebrospinal fluid (CSF) samples of HIV/AIDS ...
Sebastián Blanco   +2 more
exaly   +5 more sources

Kidney graft failure induced by BKPyV replication despite a strong reduction of the immunosuppressive therapy

open access: yesJournal of Medical Virology, 2019
AbstractBKPyV replication is a risk factor for the development of polyomavirus‐associated nephropathy in kidney transplant recipients. Here, the case of a 42 years old Caucasian patient is described who developed a kidney allograft failure because of uncontrolled BKPyV replication 7 months after transplant despite a strong reduction of the ...
Valeria Pietropaolo   +2 more
exaly   +5 more sources

The role of the DE and EF loop of BKPyV VP1 in the serological cross-reactivity between subtypes

open access: yesVirus Research, 2023
BK virus (BKPyV) is a causative agent of BKPyV-associated nephropathy and graft rejections in kidney transplant patients. It establishes persistent infection in the kidneys, which can lead to reactivation in an immunosuppressed state or transmission to kidney recipients. Complications in the case of donor-derived infections can be caused by differences
Hana Španielová   +1 more
exaly   +4 more sources

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