Results 161 to 170 of about 1,873 (184)

Infection by human polyomaviruses JCPyV and BKPyV in blood donors of Argentina

Vox Sanguinis, 2023
AbstractBackground and ObjectivesA spectrum of blood‐borne infectious agents may be transmitted through transfusion of blood components from asymptomatic donors. Despite the persistence of polyomaviruses in blood cells, no studies have been conducted in Argentina to assess the risk of transfusion infection.Materials and MethodsWe investigated BKPyV and
María C. Frutos, Sebastián Blanco, Nubia Yandar Barahona, Arnaldo Mangeaud, Luis Horacio Carrizo, Sandra Gallego   +5 more
openaire   +3 more sources

Caveolin- and clathrin-independent entry of BKPyV into primary human proximal tubule epithelial cells

Virology, 2016
BK polyomavirus (BKPyV) is a human pathogen that causes polyomavirus-associated nephropathy and hemorrhagic cystitis in transplant patients. Gangliosides and caveolin proteins have previously been reported to be required for BKPyV infection in animal cell models.
Linbo Zhao, Michael J Imperiale
exaly   +3 more sources

Intravenous Immunoglobulin Administration Significantly Increases BKPyV Genotype-Specific Neutralizing Antibody Titers in Kidney Transplant Recipients.

Antimicrobial Agents and Chemotherapy, 2019
BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) is one of the major causes of kidney graft dysfunction, and there are no BKPyV-specific antiviral therapies available.
Bruno Moulin, Ilies Benotmane, Sophie Caillard   +2 more
exaly   +2 more sources

The detection of BKPyV genotypes II and IV after renal transplantation as a simple tool for risk assessment for PyVAN and transplant outcome already at early stages of BKPyV reactivation

Journal of Clinical Virology, 2019
After reactivation the BK-polyomavirus (BKPyV) associated nephropathy (PyVAN) is observed in 1-10% of renal transplant recipients, of which up to 80% undergo graft failure. BKPyV reactivation after renal transplantation was associated with donor-derived serotypes against which the recipient has no immunological protection.
Johannes Korth, Olympia Evdoxia Anastasiou, Jan Hinrich Bräsen, Alexandra Brinkhoff, Ulrich Lehmann, Andreas Kribben, Ulf Dittmer, Jens Verheyen, Benjamin Wilde, Sandra Ciesek, Oliver Witzke, Marek Widera   +11 more
openaire   +3 more sources

Human polyomavirus 9 as a potential threat in kidney transplant recipients; lessons from BKPyV

Transplant Immunology, 2023
As a therapeutic method, kidney transplantation significantly improved the life quality and prognosis of patients with the end-stage renal disease. Since a key element in stable kidney transplantation is continuous therapy with immunosuppressive agents, an inhibited immune response makes patients vulnerable to opportunistic viral and bacterial ...
Mohammad Hossein, Razizadeh, Alireza, Tabibzadeh   +1 more
openaire   +2 more sources

Association Between BKPyV Serotype I Antibody Level and Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

Viral Immunology, 2017
To determine the association between BK polyomavirus (BKPyV) types 1 and 4 capsid antibody and natalizumab-associated progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis (MS), serum samples were obtained from 10 natalizumab-associated PML cases and 130 control MS patients treated with natalizumab, and 82 control MS ...
Ruggero Capra, Carlo Pozzilli, Raphael P Viscidi   +2 more
exaly   +3 more sources

Development and validation of a risk assessment tool for BKPyV Replication in allogeneic stem cell transplant recipients

Transplant Infectious Disease, 2020
AbstractBackgroundBK polymavirus (BKPyV), a member of the family Polyomaviridae, is associated with increased morbidity and mortality in allogeneic stem cell transplant recipients.MethodsIn our previous retrospective study of 2477 stem cell transplant patients, BKPyV replication independently predicted chronic kidney disease and poor survival.
Ala Abudayyeh, Heather Lin, Maen Abdelrahim, Gabriela Rondon, Borje S. Andersson, Charles S. Martinez, Valda D. Page, Jeffrey J. Tarrand, Dimitrios P. Kontoyiannis, David Marin, Betul Oran, Amanda Olson, Roy Jones, Uday Popat, Richard E. Champlin, Roy F. Chemaly, Elizabeth J. Shpall, Katayoun Rezvani   +17 more
openaire   +2 more sources

Detection of human JCPyV and BKPyV in diffuse large B-cell lymphoma of the GI tract

European Journal of Clinical Microbiology & Infectious Diseases, 2013
Previous studies have demonstrated that infection with human polyomavirus, such as JCPyV and BKPyV, might be associated with various human tumors. However, an association between human JCPyV and BKPyV infection and diffuse large B-cell lymphoma (DLBCL) has not been reported.
C E, Tseng, C M, Yeh, C Y, Fang, J, Shay, P L, Chen, M C, Lin, D, Chang, M, Wang   +7 more
openaire   +2 more sources

#1560 Unveiling donor-originated BKPyV viremia in kidney transplant recipients

Nephrology Dialysis Transplantation
Abstract Background and Aims BK Polyomavirus (BKPyV) is of notable concern in kidney transplant recipients, as it can lead to BKPyV DNAemia and progress to BKPyV-associated nephropathy (BKPyVAN).
Wouter Moest, Lianne Messchendorp, Helma Dolmans, Maarten Christiaans, Arjan van Zuilen, M Kho, Jan-Stephan F Sanders, M C W Feltkamp, Aiko De Vries, Joris Rotmans   +9 more
openaire   +1 more source

BK Polyomavirus (BKPyV) Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without new-onset BKPyV-DNAemia: A Swiss Transplant Cohort Study.

Collaborators "Swiss Transplant Cohort Study": Annalisa Berzigotti, Guido Stirnimann , Vanessa Banz, Guido Beldi (UVCM Department of Visceral Surgery and Medicine).
Hillenbrand, Caroline A, Bani, Dorssa Akbari, Follonier, Océane, Kaur, Amandeep, Weissbach, Fabian H, Wernli, Marion, Wilhelm, Maud, Leuzinger, Karoline, Binet, Isabelle, Bochud, Pierre-Yves, Golshayan, Dela, Hirzel, Cédric, Manuel, Oriol, Mueller, Nicolas J, Schaub, Stefan, Schachtner, Thomas, Van Delden, Christian, Hirsch, Hans H   +17 more
openaire   +1 more source