Results 71 to 80 of about 2,252 (197)

Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor

open access: yesVirology Journal, 2020
Background BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions ...
Elias Myrvoll Lorentzen   +7 more
doaj   +1 more source

Importance of molecular diagnostic of viral infections in renal transplant recipients [PDF]

open access: yes, 2019
Renal transplantation has for patients with end-stage renal disease significant survival and quality of life benefits, compared to dialysis. One of the most important complications after renal transplantation is the rejection of the kidney, also known as
Rurenga-Gard, Lilli
core   +2 more sources

Monitoring of plasma Torque teno virus, total Anelloviridae and Human Pegivirus 1 viral load for the prediction of infectious events and acute graft versus host disease in the allogeneic hematopoietic stem cell transplantation setting [PDF]

open access: yes, 2023
Anelloviridae and Human Pegivirus 1 (HPgV-1) blood burden have been postulated to behave as surrogate markers for immunosuppression in transplant recipients. Here, we assessed the potential utility plasma Torque teno virus (TTV), total Anelloviridae (TAV)
Albert, Eliseo   +7 more
core   +1 more source

In Vitro Generation of BK polyomavirus-specific T cells for adoptive cell therapy in refractory cystitis hemorrhagic patients after hematopoietic stem cell transplantation

open access: yesBMC Immunology, 2022
Introduction BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option.
Maryam Mohammadi Najafabadi   +4 more
doaj   +1 more source

Polyomavirus JCPyV and Its Role in the Urinary Tract [PDF]

open access: yes, 2022
Polyomaviruses are the smallest closed-circular supercoiled double-stranded viruses found in the human microbiota. The polyomavirus JC (JCPyV) is most commonly found within the urinary tract, and prior studies estimate that 20-80% of older adults carry ...
Mormando, Rita Lauren
core   +1 more source

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

open access: yesNeuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen   +7 more
wiley   +1 more source

Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection.

open access: yesPLoS Pathogens, 2012
BK polyomavirus (BKPyV) is an emerging pathogen whose reactivation causes severe disease in transplant patients. Unfortunately, there is no specific anti-BKPyV treatment available, and host cell components that affect the infection outcome are not well ...
Mengxi Jiang   +3 more
doaj   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin   +12 more
wiley   +1 more source

Interferon-alpha and MxA inhibit BK polyomavirus replication by interaction with polyomavirus large T antigen

open access: yesBiomedical Journal
Introduction: BK Polyomavirus (BKPyV) infection is a common complication in kidney transplant recipients and can result in poor outcomes and graft failure. Currently, there is no known effective antiviral agent.
Hsin-Hsu Wu   +7 more
doaj   +1 more source

Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta   +9 more
wiley   +1 more source

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