Results 71 to 80 of about 1,873 (184)
Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection.
PLoS Pathogens, 2012 BK polyomavirus (BKPyV) is an emerging pathogen whose reactivation causes severe disease in transplant patients. Unfortunately, there is no specific anti-BKPyV treatment available, and host cell components that affect the infection outcome are not well ...
Mengxi Jiang +3 more
doaj +1 more source
Viruses, 2022 BK polyomavirus (BKPyV) is a human DNA virus generally divided into twelve subgroups based on the genetic diversity of Viral Protein 1 (VP1). BKPyV can cause polyomavirus-associated nephropathy (PVAN) after kidney transplantation.
Olga Mineeva-Sangwo +7 more
doaj +1 more source
Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta +9 more
wiley +1 more source
Antigenic cross-reactivity among MCPyV-, BKPyV- and JCPyV-LPs.
, 2015 Hyperimmune sera were obtained from rats that were immunized with MCPyV-, BKPyV- and JCPyV-LPs, respectively. Titers of anti-MCPyV-, BKPyV- and JCPyV-LP-IgG were determined by ELISA.
Michiyo Kataoka (485324) +9 more
core +1 more source
Organ Transplantation: Current Status, Challenges, and Future Prospects
MedComm, Volume 7, Issue 1, January 2026.Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
BKPyV is mainly released into the apical compartment.
, 2023 (A) Polarized RPTECs were apically infected (MOI 0.3) and supernatants were collected at the indicated timepoints for BKPyV-DNA load (log 10 copies/ml) determination by qPCR.
Christine Hanssen Rinaldo (16892416) +2 more
core +1 more source
Biomedical JournalIntroduction: BK Polyomavirus (BKPyV) infection is a common complication in kidney transplant recipients and can result in poor outcomes and graft failure. Currently, there is no known effective antiviral agent.
Hsin-Hsu Wu +7 more
doaj +1 more source
BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing
Viruses, 2020 Human BK polyomavirus (BKPyV) prevalence has been increasing due to the introduction of more potent immunosuppressive agents in transplant recipients, and its clinical interest. BKPyV has been linked mostly to polyomavirus-associated hemorrhagic cystitis,
Joan Martí-Carreras +5 more
doaj +1 more source
The K68S mutation targets BKPyV to the SV40 receptor GM1.
, 2013 STD difference spectra of (A) BKPyV K68S with GD3, (B and C, respectively) BKPyV K68S and SV40 with GM1. (D) SV40-GM1 off-resonance spectrum. A 50-fold excess of oligosaccharide was used for each spectrum.
Bärbel S. Blaum (114952) +10 more
core +1 more source
, 2022 Limited understanding of bladder cancer aetiopathology hampers progress in reducing incidence. BK polyomavirus (BKPyV) is a common childhood infection that can be reactivated in the adult kidney leading to viruria.
Baker, Simon +10 more
core +1 more source