Results 61 to 70 of about 2,252 (197)

Review on the role of the human Polyomavirus JC in the development of tumors [PDF]

, 2017
Almost one fifth of human cancers worldwide are associated with infectious agents, either bacteria or viruses, and this makes the possible association between infections and tumors a relevant research issue.
Manola Comar, Pasquale Ferrante, Serena Delbue   +2 more
core   +1 more source

Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells [PDF]

Open Biology, 2015
BK polyomavirus (BKPyV) is a member of a family of potentially oncogenic viruses, whose reactivation can cause severe pathological conditions in transplant patients, leading to graft rejection. As with many non-enveloped viruses, it is assumed that virus
Gareth L. Evans, Laura G. Caller, Victoria Foster, Colin M. Crump   +3 more
doaj   +1 more source

Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus

Journal of Immunology Research, 2022
Multiple sclerosis (MS) is a neurological disease characterized by immune dysregulations. Different viruses may act as MS triggering agents. MS patients respond differently to distinct viruses. The aim of our study is to verify the association between the polyomavirus BKPyV and MS, together with other neurological diseases, through the investigation of
Bononi, Ilaria, Mazzoni, Elisa, Pietrobon, Silvia, Iaquinta, Maria Rosa, Caselli, Andrea, Torreggiani, Elena, Pugliatti, Maura, Casetta, Ilaria, Castellazzi, Massimiliano, Granieri, Enrico, Martini, Fernanda, Tognon, Mauro   +11 more
openaire   +4 more sources

Pre-Transplantation Assessment of BK Virus Serostatus: Significance, Current Methods, and Obstacles

Viruses, 2019
The immunosuppression required for graft tolerance in kidney transplant patients can trigger latent BK polyomavirus (BKPyV) reactivation, and the infection can progress to nephropathy and graft rejection.
Fatima Dakroub, Antoine Touzé, Haidar Akl, Etienne Brochot   +3 more
doaj   +1 more source

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-kB by Merkel Polyomavirus small Tumour antigen [PDF]

, 2017
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with a high metastatic potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV), through expression of the virus-encoded tumour antigens.
Agou, Akira, Becker, Bossuyt, Bowie, Chang, Chen, Cohen, Cohen, DeCaprio, Dikic, Dikic, Fischer, Garcea, Harris, Harris, Hatzivassiliou, Hesbacher, Israël, Jain, Klemke, Macdonald, Macdonald, Macdonald, Macdonald, Macdonald, Macdonald, Marshall, McFadden, McFadden, Moore, Moore, Moore, Perkins, Qi, Roberts, Scott, Senechal, Wadzinski, Whitehouse, Whitehouse, Whitehouse, Wu   +42 more
core   +3 more sources

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, EarlyView.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

Human polyomavirus BKPyV and JCPyV serostatus has no impact on women´s human papillomavirus infection outcome

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionPolyomaviruses have both structural and functional similarities with papillomaviruses. Accordingly, their role in human papillomavirus (HPV) associated malignancies has been studied with conflicting results. Our goal was to disclose any association between BK (BKPyV) and/or JC (JCPyV) polyomavirus serology and HPV data derived from Finnish ...
Hanna K. Laine, Hanna K. Laine, Tim Waterboer, Kari Syrjänen, Seija Grenman, Karolina Louvanto, Karolina Louvanto, Stina Syrjänen, Stina Syrjänen   +8 more
openaire   +6 more sources

Prevalence and Molecular Profiling of Merkel Cell Polyomavirus in Patients With Monkeypox Virus Infection

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Mpox, caused by Monkeypox virus (MPXV), is associated with mucosal involvement and immune modulation that may influence viral coinfections. Merkel Cell Polyomavirus (MCPyV), a ubiquitous virus capable of lifelong persistence, was investigated in 66 Mpox patients enrolled at Lazzaro Spallanzani National Institute for Infectious Diseases (Rome ...
Sara Passerini, Davide Mariotti, Sara Messina, Valentina Mazzotta, Giulia Matusali, Andrea Antinori, Valeria Pietropaolo, Fabrizio Maggi, Luigi Rosa   +8 more
wiley   +1 more source

Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus. [PDF]

, 2014
A fifth of worldwide cancer cases have an infectious origin, with viral infection being the foremost. One such cancer is Merkel cell carcinoma (MCC), a rare but aggressive skin malignancy.
Abdul-Sada, H, Adzahar, NS, Knight, LM, Macdonald, A, Nwogu, N, Stakaitytė, G, Whitehouse, A, Wood, JJ   +7 more
core   +3 more sources

BK Polyomavirus in Pediatric Renal Transplantation—What We Know and What We Do Not

Biomedicines
BK polyomavirus (BKPyV) is still a real threat in the management of kidney transplantation. Immunosuppressive treatment disrupts the equilibrium between virus replication and immune response, and uncontrolled BKPyV replication leads to nephropathy (BKPyV
Benedetta Chiodini, Pauline Guillaume-Gentil, Charlotte Vanhomwegen, Elise Hennaut, Ksenija Lolin, Nathalie Tram, Alain Le Moine, Khalid Ismaili   +7 more
doaj   +1 more source