BK polyomavirus infection promotes growth and aggressiveness in bladder cancer
Virology Journal, 2020 Background Recent studies have confirmed the integration of the BK polyomavirus (BKPyV) gene into the cellular genome of urothelial carcinomas in transplant recipients, further confirming the correlation between BKPyV and urothelial carcinomas after ...
Yigang Zeng +3 more
doaj +1 more source
Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication [PDF]
, 2015 License:Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)Background: The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein.
Barbara van Loon +9 more
core +2 more sources
Novel human polyomaviruses in pregnancy: Higher prevalence of BKPyV, but no WUPyV, KIPyV and HPyV9 [PDF]
Journal of Clinical Virology, 2012 Immunosuppression due to pregnancy may lead to higher susceptibility to infections and reactivation of latent infections, such as BK polyomavirus (BKPyV). There is lack of information about the prevalence of novel human polyomavirus 9 (HPyV9), WU (WUPyV) and KI (KIPyV) during pregnancy.To study whether pregnancy results in higher prevalence of HPyV9 ...
Eszter, Csoma +3 more
openaire +2 more sources
Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast [PDF]
, 2015 Background: Eleven new human polyomaviruses (HPyVs) have been identified in the last decade. Serological studies show that these novel HPyVs sub-clinically infect humans at an early age.
Alma Gedvilaite +5 more
core +1 more source
BK virus infection and outcome following kidney transplantation in childhood [PDF]
, 2021 : BK virus associated nephropathy (BKN) is an important cause of kidney allograft failure. In a cohort of paediatric kidney transplant recipients, we aimed to understand the incidence and clinical outcome associated with BKN, as well as identify risk ...
Bhute, Vijesh J +2 more
core +3 more sources
First-In-Human, Randomized, Placebo-Controlled, SAD and MAD Trial to Evaluate Safety, Tolerability, and PK/PD Modeling of Potravitug in Healthy Adults. [PDF]
Clin Transl SciABSTRACT BK polyomavirus (BKPyV) affects 10%–30% of kidney‐transplant recipients receiving immunosuppressive therapy, potentially leading to nephropathy, graft dysfunction, graft loss, and increased mortality. Despite the medical need, no targeted therapies exist.
May M +8 more
europepmc +2 more sources
No Evidence of Human Polyomavirus 9, WU and KI DNA in Kidney and Urinary Bladder Tumour Tissue Samples [PDF]
, 2016 KAL
Bidiga, László +3 more
core +1 more source
A multivalent polyomavirus vaccine elicits durable neutralizing antibody responses in macaques [PDF]
, 2023 In 2019, there were about 100,000 kidney transplants globally, with more than a quarter of them per-formed in the United States. Unfortunately, some engrafted organs are lost to polyomavirus-associated nephropathy (PyVAN) caused by BK and JC viruses ...
Buck, Christopher B. +10 more
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2023 The reactivation of polyomavirus BK (BKPyV) contributes to increased morbidity and mortality rates of transplant patients, especially kidney transplant recipients (KTRs).
Nasrin Noshadi +4 more
doaj +1 more source
Serum IgG antibodies from pregnant women reacting to mimotopes of simian virus 40 large T antigen, the viral oncoprotein [PDF]
, 2017 Simian virus 40 (SV40) large T antigen (LT) coding sequences were revealed in different human samples, whereas SV40 antibodies (Ab) were detected in human sera of cancer patients and healthy individuals, although with a lower prevalence. Previous studies
Casali, Maria V. +11 more
core +2 more sources