Results 21 to 30 of about 2,252 (197)

Rejection after BKPyV DNAemia-Are We Treating Too Cautiously? [PDF]

Transpl Int
Moest WT, de Vries APJ, van Rijn AL, van der Helm D, Kers J, Feltkamp MCW, Rotmans JI.   +6 more
europepmc   +3 more sources

HLA-B Leader Dimorphism Predicts BK Polyomavirus Replication After Kidney Transplant. [PDF]

HLA
ABSTRACT BK polyomavirus (BKPyV) and Cytomegalovirus (CMV) often replicate after kidney transplantation, with management limited to reducing immunosuppression and risking rejection. Among genetic factors that may modulate the antiviral response, HLA evolutionary divergence (HED, allowing a greater diversity of antigen presentation) and the HLA‐B leader
Aubry A, Demey B, Helle F, Fourdinier O, Lion J, Desoutter J, Brochot E, Guillaume N.   +7 more
europepmc   +2 more sources

BKPyV-Co-Architect of the Fate of a Renal Transplant During a One-Year Observation Period. [PDF]

Int J Mol Sci
To identify BKPyV, the VP1 protein sequence was analyzed and classified into genotypes in 246 RTRs before and after RTx from deceased donors during a one-year observation period. Quantitative assessment of BKPyV was conducted via qPCR. Prior to RTx, genotypes I and IV were identified in the urine (7.27 × 106; 1.20 × 105) and in serum (5.75 × 104; 1.12 ×
Furmaga J, Kowalczyk M, Furmaga-Rokou O, Rokos CA, Zapolski T, Styczeń A, Iwan A, Matera D, Chrapko BE, Krakowski L, Jakubczak A.   +10 more
europepmc   +3 more sources

A cluster of broadly neutralizing IgG against BK polyomavirus in a repertoire dominated by IgM

Life Science Alliance, 2023
FACS sorting of patient B cells with fluorescent BKPyV VLPs, followed by 10xGenomics scRNAseq, generated a large dataset of BKPyV-specific antibody sequences, among which we were able to identify and characterize broadly neutralizing antibodies.
Ngoc-Khanh Nguyen, Marie-Claire Devilder, Laetitia Gautreau-Rolland, Cynthia Fourgeux, Debajyoti Sinha, Jeremie Poschmann, Maryvonne Hourmant, Céline Bressollette-Bodin, Xavier Saulquin, Dorian McIlroy   +9 more
doaj   +1 more source

1189. Correlation of BK polyomavirus (BKPyV)-specific Immunity and BKPyV Viruria within 6 months after Kidney Transplantation: A Prospective Cohort Study [PDF]

Open Forum Infectious Diseases, 2020
Abstract Background Since viral-specific immunity has been shown to be correlated with viral containment in solid organ transplant recipients, we investigated an association of BK polyomavirus (BKPyV)-specific immunity and BKPyV viruria in kidney transplant (KT) recipients.
Siripoon, Tanaya, Kantachuvesiri, Surasak, Apiwattanakul, Nopporn, Bruminhent, Jackrapong   +3 more
openaire   +1 more source

Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines. [PDF]

Microbiologyopen
In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Shioda S, Kasai F, Ozawa M, Ohtani A, Iemura M, Watanabe K, Kohara A.   +6 more
europepmc   +2 more sources

Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

Virology Journal, 2023
Background Human polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant recipients. Large tumor antigen (LT) is an early protein essential in the polyomavirus life cycle.
Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu, Cheng-Huang Shen, San-Yuan Chen, Chiung-Yao Fang   +7 more
doaj   +1 more source

Viral infections in prostate carcinomas in Chilean patients [PDF]

, 2015
© 2015 Rodríguez et al.Background: A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined.
A Bellizzi, A Pal, A Zambrano, Aldo Gaggero, AM Roda Husman de, AR Patel, B Akgül, C Moyret-Lalle, CK Choo, D Das, Diego Carrillo, DR Lowy, E Shtivelman, Francisco Aguayo, G Russo, GJ Leiros, H Feng, H zur Hausen, Hector Rodríguez, Iván Gallegos, J Cuzick, J Ferlay, J Hrbacek, Jorge Castillo, Jorge Levican, JS Rhim, Juan P. Muñoz, K Reiss, KF Harris, M Schmitt, M Schmitt, M Tognon, Massimo Tommasino, ML Martinez-Fierro, Mónica L. Acevedo, N Albinana-Gimenez, N Babel, N Peña, N Shahzad, NJ Whitaker, Omar Espinoza-Navarro, Oscar León, P Randhawa, R Tachezy, S Bofill-Mas, S Delbue, SK Lau, T Bethge, T Gheit, T Gheit, T Iwasaka, Tarik Gheit, V Balis, WA Knowles, WG Nelson, Y Lin   +55 more
core   +3 more sources

A systematic review. Current understanding of the infection caused by Betapolyomavirus hominis

Журнал инфектологии, 2023
Reactivation of Betapolyomavirus hominis (BKPyV) in kidney and hematopoietic stem cell recipients can lead to serious complications such as BKPyV-associated nephropathy followed by transplant rejection and BKPyV-associated hemorrhagic cystitis.
D. R. Prilepskaya, E. A. Domonova
doaj   +1 more source

Fatal BK polyomavirus-associated pneumonia: report of two cases with literature review

BMC Infectious Diseases, 2023
Background In immunocompromised populations, such as patients with AIDS and recipients of solid organ and hematopoietic stem cell transplants, BK polyomavirus (BKPyV) can reactivate and cause several diseases, which can lead to death in their severe ...
Yuchen Wang, Yiling Fang, Ziyan Yan, Renfei Xia, Wenli Zeng, Wenfeng Deng, Jian Xu, Xiaoqin Feng, Jie Peng, Yun Miao   +9 more
doaj   +1 more source