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Polarized RPTECs support BKPyV infection.
, 2023 (A) Binding and internalization of BKPyV (MOI 0.1) in polarized RPTECs at 2 hours post infection (hpi) demonstrated by immunofluorescence staining against Vp1 (4942) (red) and Na/K-ATPase (green). Scale bar is 10 μm. (B) Transmission electron micrographs
Christine Hanssen Rinaldo (16892416) +2 more
core +1 more source
The differential presence of human polyomaviruses, JCPyV and BKPyV, in prostate cancer and benign prostate hypertrophy tissues [PDF]
BMC Cancer, 2021 Abstract Background Studies have shown that human polyomavirus infection may be associated with various human cancers. We investigated the potential relationship between the prevalence of JCPyVor BKPyV and prostate cancer (PC) in patients from Taiwan.
Chenghuang Shen +7 more
openaire +3 more sources
, 2021 The BK polyomavirus (BKPyV) is ubiquitous and persists asymptomatically in the kidney. BKPyV reactivation can be seen in kidney transplant (KTx) recipients who receive immunosuppression treatments.
Nguyen, Ngoc Khanh
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Fatal BK polyomavirus-associated pneumonia: report of two cases with literature review
BMC Infectious Diseases, 2023 Background In immunocompromised populations, such as patients with AIDS and recipients of solid organ and hematopoietic stem cell transplants, BK polyomavirus (BKPyV) can reactivate and cause several diseases, which can lead to death in their severe ...
Yuchen Wang +9 more
doaj +1 more source
PLoS Pathogens, 2023 Most humans have a lifelong imperceptible BK Polyomavirus (BKPyV) infection in epithelial cells lining the reno-urinary tract. In kidney transplant recipients, unrestricted high-level replication of donor-derived BKPyV in the allograft underlies ...
Elias Myrvoll Lorentzen +2 more
doaj +1 more source
BKPyV-Co-Architect of the Fate of a Renal Transplant During a One-Year Observation Period. [PDF]
Int J Mol SciTo identify BKPyV, the VP1 protein sequence was analyzed and classified into genotypes in 246 RTRs before and after RTx from deceased donors during a one-year observation period. Quantitative assessment of BKPyV was conducted via qPCR. Prior to RTx, genotypes I and IV were identified in the urine (7.27 × 106; 1.20 × 105) and in serum (5.75 × 104; 1.12 ×
Furmaga J +10 more
europepmc +3 more sources
American Journal of Transplantation, 2017 We report a lung transplant recipient who developed BK polyoma virus (BKPyV) DNAemia and BKPyV nephropathy. With careful management of his immunosuppression he achieved significant reduction in BKPyV DNAemia and stabilization of his kidney function. He later developed a high-grade bladder cancer and shortly thereafter he experienced a major upsurge in ...
S, Kuppachi +7 more
openaire +2 more sources
Novel human polyomaviruses in pregnancy: Higher prevalence of BKPyV, but no WUPyV, KIPyV and HPyV9 [PDF]
Journal of Clinical Virology, 2012 Immunosuppression due to pregnancy may lead to higher susceptibility to infections and reactivation of latent infections, such as BK polyomavirus (BKPyV). There is lack of information about the prevalence of novel human polyomavirus 9 (HPyV9), WU (WUPyV) and KI (KIPyV) during pregnancy.To study whether pregnancy results in higher prevalence of HPyV9 ...
Eszter, Csoma +3 more
openaire +2 more sources
mSphere, 2017 BK polyomavirus (BKPyV) is a human pathogen first isolated in 1971. BKPyV infection is ubiquitous in the human population, with over 80% of adults worldwide being seropositive for BKPyV.
Linbo Zhao, Michael J. Imperiale
doaj +1 more source
Viruses, 2018 In immunosuppressed patients, BKPyV-variants emerge carrying rearranged non-coding control-regions (rr-NCCRs) that increase early viral gene region (EVGR) expression and replication capacity.
Francesco Martelli +7 more
doaj +1 more source