Results 11 to 20 of about 2,252 (197)

BKPyV DNAemia in Kidney Transplant Recipients Undergoing Regular Screening: A Single-Centre Cohort Study [PDF]

Microorganisms, 2023
Infection with BK polyomavirus (BKPyV) is a common opportunistic infection after kidney transplantation (KT) and may affect graft function. We aimed to determine the incidence, risk factors, and clinical outcomes of BKPyV DNAemia in a prospective cohort ...
Daniel B. Rasmussen, Dina L. Møller, Sebastian R. Hamm, Álvaro H. Borges, Alex C. Y. Nielsen, Nikolai S. Kirkby, Søren S. Sørensen, Susanne D. Nielsen   +7 more
doaj   +4 more sources

Control of BKPyV-DNAemia by a Tailored Viro-Immunologic Approach Does Not Lead to BKPyV-Nephropathy Progression and Development of Donor-Specific Antibodies in Pediatric Kidney Transplantation

Microorganisms
Polyomavirus BK (BKPyV)-associated nephropathy (BKPyV-nephropathy) remains a significant cause of premature kidney allograft failure. In the absence of effective antiviral treatments, current therapeutic approaches rely on immunosuppression (IS ...
Michela Cioni, Stella Muscianisi, Marica De Cicco, Sabrina Basso, Hans H. Hirsch, Iris Fontana, Laura Catenacci, Jessica Bagnarino, Mariangela Siciliano, Oriana Montana Lampo, Gloria Acquafredda, Lou Tina Diana Boti, Jessica Rotella, Eleonora Bozza, Jennifer Zumelli, Kristiana Mebelli, Fausto Baldanti, Massimo Cardillo, Marco Zecca, Arcangelo Nocera, Mario Luppi, Enrico Verrina, Fabrizio Ginevri, Patrizia Comoli   +23 more
doaj   +3 more sources

Clinically Relevant Reactivation of Polyomavirus BK (BKPyV) in HLA-A02-Positive Renal Transplant Recipients Is Associated with Impaired Effector-Memory Differentiation of BKPyV-Specific CD8+ T Cells.

PLoS Pathogens, 2016
Polyomavirus BK (BKPyV) frequently reactivates in immunosuppressed renal transplant recipients (RTRs) and may lead to graft loss due to BKPyV-induced interstitial nephritis (BKVN). Little is known on the differentiation of CD8+ T cells targeting BKPyV in
Michiel C van Aalderen, Ester B M Remmerswaal, Kirstin M Heutinck, Anja Ten Brinke, Mariet C W Feltkamp, Neelke C van der Weerd, Karlijn A M I van der Pant, Frederike J Bemelman, René A W van Lier, Ineke J M Ten Berge   +9 more
doaj   +5 more sources

Clinical Associations and Coexistence of Polyomavirus DNAemia with EBV and CMV in Pediatric Hematology/Oncology Patients, Including HCT Recipients—A Pilot Study [PDF]

Pathogens
Polyomaviruses (BKPyV and JCPyV) and herpesviruses (EBV, CMV) usually infect people during childhood, and may be associated, in some clinical states, with immunocompromised individuals.
Tomasz Bogiel, Mateusz Rzepka, Dagmara Depka-Radzikowska, Patrycja Zalas-Więcek, Krzysztof Czyżewski, Monika Richert-Przygońska, Jan Styczyński, Robert Dębski, Elżbieta Grześk, Grzegorz Grześk, Piotr Kanarek, Agnieszka Krawczyk   +11 more
doaj   +2 more sources

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells. [PDF]

PLoS Pathogens
BK polyomavirus (BKPyV) is a ubiquitous human virus that establishes a persistent infection in renal tubular epithelial cells and mainly causes disease in kidney transplant recipients.
Elias Myrvoll Lorentzen, Stian Henriksen, Christine Hanssen Rinaldo   +2 more
doaj   +3 more sources

Specific and quantitative detection of Human polyomaviruses BKPyV and JCPyV in the healthy Pakistani population [PDF]

Virology Journal, 2017
Background The BK Polyomavirus (BKPyV) and JC polyomavirus (JCPyV) infections are widespread in human population and have been associated with severe kidney and brain disorders, respectively.
Iqra Hussain, Fareeda Tasneem, Muhammed Umer, Ayesha Pervaiz, Muslim Raza, Muhammad Imran Arshad, Naveed Shahzad   +6 more
doaj   +4 more sources

Specific Detection of Serum Antibodies against BKPyV, A Small DNA Tumour Virus, in Patients Affected by Choroidal Nevi

Frontiers in Microbiology, 2017
Ocular or choroidal nevus (CN) is a rare benign neoplastic lesion of the eye. The cause of CN onset/progression, which arises from the transformation of ocular melanocytes, is not known. A fraction of CN patients may develop uveal melanoma. The objective
Silvia Pietrobon, Ilaria Bononi, Paolo Perri   +2 more
exaly   +3 more sources

The risk factors associated with post-transplantation BKPyV nephropathy and BKPyV DNAemia: a prospective study in kidney transplant recipients

BMC Infectious Diseases
Background BK polyomavirus (BKPyV) infection after kidney transplantation can lead to serious complications such as BKPyV-associated nephropathy (BKPyVAN) and graft loss.
Camilla Lorant, Justina Zigmantaviciute, Naima Ali, Ursa Bonnevier, Mattias Tejde, Bengt von Zur-Mühlen, Britt-Marie Eriksson, Anders Bergqvist, Gabriel Westman   +8 more
doaj   +4 more sources

Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples. [PDF]

J Med Virol
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Guimarães ACS, Rodrigues LLS, Campos LB, Martinelli KG, Oliveira NSC, Martin Kast W, Gaydos CA, de Jesus CS, Pilotto JH, Morgado MG, Gheit T, de Paula VS.   +11 more
europepmc   +2 more sources

Simultaneous BK Polyomavirus (BKPyV)-associated nephropathy and hemorrhagic cystitis after living donor kidney transplantation [PDF]

Journal of Clinical Virology, 2016
BK polyomavirus (BKPyV) commonly reactivates after kidney transplantation, and can cause polyomavirus-associated nephropathy (PyVAN), whereas after allogeneic stem cell transplantation the most frequent manifestation of BKPyV is polyomavirus-associated ...
Auvinen, Eeva, Helanterä, Ilkka, Hirsch, Hans H., Lautenschlager, Irmeli, Lempinen , Marko, Mannonen, Laura, Ortiz, Fernanda, Räisänen-Sokolowski, Anne, Wernli, Marion   +8 more
core   +6 more sources