Results 11 to 20 of about 7,824 (162)

First report of a carbapenem-resistant Serratia sarumanii clinical strain co-harboring blaKPC-2 and blaNDM-1 genes in China [PDF]

Current Research in Microbial Sciences
Carbapenem-resistant Enterobacteriaceae (CRE), particularly those co-harboring multiple carbapenemase genes, pose a significant global health threat. However, the coexistence of blaKPC-2 and blaNDM-1 in Serratia sarumanii has not been previously reported.
Xiao Liu, Zhen Liu, Xuemei Bai, He Gao, Zhiwen Sun, Duochun Wang   +5 more
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A novel plasmid carrying carbapenem-resistant gene blaKPC-2 in Pseudomonas aeruginosa

Infection and Drug Resistance, 2019
Yan-Yan Hu, Qi Wang, Qiao-Ling Sun, Gong-Xiang Chen, Rong Zhang2nd Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaAbstract: A carbapenem-resistant Pseudomonas aeruginosa ...
Hu YY, Wang Q, Sun QL, Chen GX, Zhang R
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Comparison of Four Carbapenemase Detection Methods for blaKPC-2 Variants

Microbiology Spectrum, 2021
Recently, various blaKPC-2 variants resistant to ceftazidime-avibactam have begun to emerge in clinical settings, but it is unclear which testing method is most appropriate for detecting these variants.
Li Ding, Qingyu Shi, Renru Han, Dandan Yin, Shi Wu, Yang Yang, Yan Guo, Demei Zhu, Fupin Hu   +8 more
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Complete Genome Sequences of Two Novel KPC-2-Producing IncU Multidrug-Resistant Plasmids From International High-Risk Clones of Escherichia coli in China

Frontiers in Microbiology, 2021
The rapidly increasing prevalence of Klebsiella pneumoniae carbapenemase 2 (KPC-2)-producing bacteria has become a serious challenge to public health. Currently, the blaKPC–2 gene is mainly disseminated through plasmids of different sizes and replicon ...
Wenhao Wu, Wenhao Wu, Lingling Lu, Wenjia Fan, Chun Chen, Dazhi Jin, Hongying Pan, Xi Li   +7 more
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Carbapenem-resistant Citrobacter freundii harboring blaKPC−2 and blaNDM−1: a study on their transferability and potential dissemination via generating a transferrable hybrid plasmid mediated by IS6100

Frontiers in Microbiology, 2023
IntroductionThe increase in clinical Enterobacteriaceae with dual carbapenemase has become a serious healthcare concern. It is essential to characterize the transferability and potential dissemination of blaKPC−2- and blaNDM−1-coharboring carbapenem ...
Feilong Zhang, Feilong Zhang, Feilong Zhang, Ziyao Li, Ziyao Li, Ziyao Li, Xinmeng Liu, Xinmeng Liu, Xinmeng Liu, Yanning Hu, Yanning Hu, Yanning Hu, Jiankang Zhao, Jiankang Zhao, Yulin Zhang, Yulin Zhang, Yanyan Fan, Yanyan Fan, Zichen Lei, Zichen Lei, Zichen Lei, Xinrui Yang, Xinrui Yang, Xinrui Yang, Zhihua Li, Zhihua Li, Zhihua Li, Chen Li, Chen Li, Chen Li, Chen Li, Yongli Wu, Yongli Wu, Yongli Wu, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu   +38 more
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Detection of blaKPC-2 in a carbapenem-resistant Kluyvera georgiana [PDF]

Journal of Antimicrobial Chemotherapy, 2012
Faculdade de Farmacia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Unidade de Microbiologia e Biologia Molecular, Servico de Patologia Clinica, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Infectious Diseases Service, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Infection Control Service, Hospital Sao ...
Vanessa Bley, Ribeiro, Alexandre P, Zavascki, Carolina Silva, Nodari, Ana Maria, Sandri, Marilaine Peres, Silva, Juliana Coutinho, Campos, Jorge Luiz Mello, Sampaio, Afonso Luís, Barth   +7 more
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Multiple Novel Ceftazidime-Avibactam-Resistant Variants of blaKPC-2-Positive Klebsiella pneumoniae in Two Patients

Microbiology Spectrum, 2022
As the first-line antimicrobial agent for the infection caused by carbapenem-resistant Enterobacterales, ceftazidime-avibactam develops drug resistance during its ever-growing clinical use.
Qingyu Shi, Renru Han, Yan Guo, Yang Yang, Shi Wu, Li Ding, Rong Zhang, Dandan Yin, Fupin Hu   +8 more
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Carriage of blaKPC-2 by a virulence plasmid in hypervirulent Klebsiella pneumoniae [PDF]

Journal of Antimicrobial Chemotherapy, 2018
To characterize a plasmid in a K1 hypervirulent Klebsiella pneumoniae (HvKP) strain encoding both hypervirulence and carbapenem resistance phenotypes.Plasmids from HvKP strain KP70-2 were subjected to whole-plasmid sequencing using both the Illumina NextSeq 500 sequencing platform and Nanopore MinION sequencer platforms.A hybrid virulence- and ...
Ning, Dong, Dachuan, Lin, Rong, Zhang, Edward Wai-Chi, Chan, Sheng, Chen   +4 more
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Emergence of a Clinical Escherichia coli Sequence Type 131 Strain Carrying a Chromosomal blaKPC–2 Gene

Frontiers in Microbiology, 2020
Objectives: Bacteria carrying the Klebsiella pneumoniae carbapenemase genes have rapidly spread worldwide and have become a great threat to public health. The blaKPC–2 gene has been primarily located on plasmids cocirculating in various strains. However,
Dairong Wang, Dairong Wang, Xinli Mu, Xinli Mu, Ying Chen, Ying Chen, Dongdong Zhao, Dongdong Zhao, Ying Fu, Ying Fu, Yan Jiang, Yan Jiang, Yiwei Zhu, Yiwei Zhu, Jingjing Quan, Jingjing Quan, Xiaoting Hua, Xiaoting Hua, Guofeng Mao, Xi Li, Yunsong Yu, Yunsong Yu   +21 more
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Clonal Dissemination of Aeromonas hydrophila With Binary Carriage of blaKPC-2-Bearing Plasmids in a Chinese Hospital

Frontiers in Microbiology, 2022
Dissemination of the Klebsiella pneumoniae carbapenemase (KPC)-encoding gene among Enterobacterales is common but relatively rare in Aeromonas spp. In this study, we characterized two KPC-2-producing Aeromonas hydrophila strains (Ah2101 and Ah2111), each
Zhijiang Xu, Weiyi Shen, Rong Zhang, Jiachang Cai   +3 more
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