Results 171 to 180 of about 15,201 (184)

Urinary BLCA-4 level is useful to detect upper urinary tract urothelial cell carcinoma

Actas Urológicas Españolas (English Edition), 2012
Upper urinary tract urothelial cell carcinomas (UUT-UCCs) are rare but usually invasive at diagnosis. Early diagnosis of UUT-UCCs is thus warranted. UUT has the same embryological origin with bladder and BLCA-4 is a highly sensitive and specific marker for bladder cancer.
C-C, Feng, Z, Wu, H-W, Jiang, H, Wen, M, Guan, Q, Ding   +5 more
openaire   +2 more sources

Differentiating bladder cancer (BLCA) tumor immune microenvironment (TME) profiles based on predicted intrinsic radiosensitivity (RS).

Journal of Clinical Oncology, 2023
e16622 Background: Radiation is an essential part of organ preservation therapy for muscle-invasive BLCA patients. There is increasing interest in use of immunotherapy in this setting and defining biomarkers of RS and immunity will be crucial to guide patient selection.
Winston Vuong, Shinjini Ganguly, Aysegul Balyimez, Ahmed Halima, Cassandra Kerr, Mark L. Day, Scott A. Tomlins, Petros Grivas, Shilpa Gupta, Timothy An-thy Chan, Babal Jha, Omar Y. Mian   +11 more
openaire   +1 more source

Biodistributions of intact monoclonal antibodies and fragments of BLCA-38, a new prostate cancer directed antibody

Cancer Immunology, Immunotherapy, 2004
Monoclonal antibodies (MAbs) are used for targeting agents to tumours while minimizing normal tissue exposure.A new anti-prostate cancer MAb, BLCA-38, was radioiodinated (I125) and assessed for its ability to target subcutaneous human prostate cancer (DU-145) xenografts after systemic intraperitoneal administration.
Teresa, Carter, Katy, Sterling-Levis, Kim, Ow, Larissa, Doughty, Meghan, Hattarki, Deborah, Shapira, Dean, Hewish, Alexander A, Kortt, Pamela J, Russell   +8 more
openaire   +2 more sources

Detection of bladder cancer using a novel nuclear matrix protein, BLCA-4.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2000
We have identified previously six nuclear matrix proteins (NMPs) that are bladder cancer specific. In this study, we analyzed the expression of one of these proteins, BLCA-4, in bladder tumors and normal bladder tissue. We also examined the appearance of BLCA-4 in the urine as a biomarker for bladder cancer.
B R, Konety, T S, Nguyen, R, Dhir, R S, Day, M J, Becich, W M, Stadler, R H, Getzenberg   +6 more
openaire   +1 more source

The Prognostic Hub Gene POLE2 Promotes BLCA Cell Growth via the PI3K/AKT Signaling Pathway

Combinatorial Chemistry & High Throughput Screening
Background::BLCA is a common urothelial malignancy characterized by a high recurrence rate. Despite its prevalence, the molecular mechanisms underlying its development remain unclear.Aims::This study aimed to explore new prognostic biomarkers and investigate the underlying mechanism of bladder cancer (BLCA).Objective::The objective of this study is to ...
Dongzhen, Jiang, Huawei, Zhang, Bingde, Yin, Minke, He, Xuwei, Lu, Chang, He   +5 more
openaire   +2 more sources

BLCA-4 and UBC combined detection for early diagnosis of bladder cancer.

Journal of biological regulators and homeostatic agents, 2016
The objective of the present study was to report the clinical significance of bladder cancer specific nuclear matrix protein 4 (BLCA-4) and urinary bladder cancer (UBC) on early diagnosis of bladder cancers. Enzyme-linked immunosorbent assay (ELISA) was used to detect BLCA-4 and UBC of 56 bladder cancer patients and 26 patients with urinary tract ...
L, Cui, M M, Sun, Z H, Zhao, J P, Yang, Y P, Zheng, L L, He, K S, Chen, Q X, Fan   +7 more
openaire   +1 more source

Pan-cancer analysis of PLAU indicates its potential prognostic value and correlation with neutrophil infiltration in BLCA

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
PLAU is known as a selected serine protease converting plasminogen to plasmin. The role of PLAU in the development of pan-cancer, especially bladder urothelial carcinoma (BLCA) remains unclear.A variety of online tools and cancer databases, including TCGA, GETx, HPA database, GSCALite, UALCAN, ESTIMATE, CIBERSORT, ssGSEA algorithms and SangerBox ...
Ke, Shi, Jianda, Zhou, Man, Li, Wenguang, Yan, Jiaqi, Zhang, Xiulan, Zhang, Li, Jiang   +6 more
openaire   +2 more sources

SHM role in Bridge Life Cycle Analysis (BLCA)

2008
Mohammed Ettouney, Sreenivas Alampalli
openaire   +1 more source

Functional Characterization of the Bladder Cancer Marker, BLCA-4

Journal of Urology, 2005
openaire   +1 more source

Retraction: Functional Characterization of the Bladder Cancer Marker, BLCA-4

Clinical Cancer Research, 2013
openaire   +1 more source