Results 11 to 20 of about 15,495 (203)
Overexpressed pseudogene MT1L associated with tumor immune infiltrates and indicates a worse prognosis in BLCA [PDF]
World Journal of Surgical Oncology, 2021 Background BLCA is a common cancer worldwide, and it is both aggressive and fatal. Immunotherapy (ICT) has achieved an excellent curative effect in BLCA; however, only some BLCA patients can benefit from ICT.
Yanpeng Ding +9 more
doaj +4 more sources
HYAL3 as a potential novel marker of BLCA patient prognosis
BMC Genomic Data, 2022 Background It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA.
Jun-peng Liu +3 more
doaj +3 more sources
Exploration of neutrophil-associated genes in the prognosis of bladder urothelial carcinoma based on a machine learning and multi-omics data integration framework [PDF]
Human GenomicsBackground Bladder urothelial carcinoma (BLCA) is a prevalent malignancy. The poor performance of existing therapeutic approaches in the advanced stages of BLCA underscores the critical need for more sensitive and precise biomarkers to improve patient ...
Muya Ran +7 more
doaj +2 more sources
Development of a prognostic model related to mitochondria and programmed cell death-related genes in bladder cancer [PDF]
Frontiers in GeneticsBackgroundVarious forms of programmed cell death (PCD) play a crucial role in regulating the development and spread of cancer, with mitochondria serving as key organelles involved in executing PCD.
Xuwei Zhao +8 more
doaj +2 more sources
Pathogenic and Diagnostic Potential of BLCA-1 and BLCA-4 Nuclear Proteins in Urothelial Cell Carcinoma of Human Bladder [PDF]
Advances in Urology, 2012 Transitional cell carcinoma (TCC) of the bladder is one of the most common malignancies of genitourinary tract. Patients with bladder cancer need a life-long surveillance, directly due to the relatively high recurrence rate of this tumor. The use of cystoscopy represents the gold standard for the followup of previously treated patients.
Matteo Santoni +7 more
openaire +6 more sources
Cancer & Metabolism, 2023 Background Bladder cancer (BLCA) research in Koreans is still lacking, especially in focusing on the prediction of BLCA. The current study aimed to discover metabolic signatures related to BLCA onset and confirm its potential as a biomarker.
Youngmin Han +7 more
doaj +1 more source
BMC Cancer, 2022 Background Pituitary tumor transforming gene-1 (PTTG1) transcription factor is identified as carcinogenic and associated with tumor invasiveness, but its role in bladder cancer (BLCA) remains obscure.
Jian-Di Li +10 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, 2023 AbstractRecently, epigenetics showed essential roles in tumour microenvironment (TME) and immunotherapy response, however, the functions of RNA 5‐methylcytosine (m5C) modification in TME remains unknown. According to 13 m5C regulators, we evaluated 412 BLCA patients from The Cancer Genome Atlas (TCGA) database.
Dali Yan +7 more
openaire +2 more sources
Functional Characterization of the Bladder Cancer Marker, BLCA-4 [PDF]
Clinical Cancer Research, 2004 Abstract Introduction: Bladder cancer is a common disease of the genitourinary tract for which the development of a noninvasive detection technique would have a significant impact on disease management. One of our previously identified bladder cancer-specific proteins, BLCA-4, appears to be associated with a “field effect” of the disease,
Thu-Suong, Van Le +4 more
openaire +2 more sources
BMC Cancer, 2022 Background Bladder cancer (BLCA) is one of the most common genitourinary malignancies in the world, but its pathogenic genes have not been fully identified and the treatment outcomes are still unsatisfactory. Although the members of 2', 5'-oligoadenylate
Lijuan Gao +11 more
doaj +1 more source