Results 11 to 20 of about 15,201 (184)
Overexpressed pseudogene MT1L associated with tumor immune infiltrates and indicates a worse prognosis in BLCA [PDF]
World Journal of Surgical Oncology, 2021 Background BLCA is a common cancer worldwide, and it is both aggressive and fatal. Immunotherapy (ICT) has achieved an excellent curative effect in BLCA; however, only some BLCA patients can benefit from ICT.
Yanpeng Ding +9 more
doaj +4 more sources
HYAL3 as a potential novel marker of BLCA patient prognosis
BMC Genomic Data, 2022 Background It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA.
Jun-peng Liu +3 more
doaj +3 more sources
Pathogenic and Diagnostic Potential of BLCA-1 and BLCA-4 Nuclear Proteins in Urothelial Cell Carcinoma of Human Bladder [PDF]
Advances in Urology, 2012 Transitional cell carcinoma (TCC) of the bladder is one of the most common malignancies of genitourinary tract. Patients with bladder cancer need a life-long surveillance, directly due to the relatively high recurrence rate of this tumor. The use of cystoscopy represents the gold standard for the followup of previously treated patients.
Matteo Santoni +7 more
openaire +6 more sources
Journal of Cellular and Molecular Medicine, 2023 AbstractRecently, epigenetics showed essential roles in tumour microenvironment (TME) and immunotherapy response, however, the functions of RNA 5‐methylcytosine (m5C) modification in TME remains unknown. According to 13 m5C regulators, we evaluated 412 BLCA patients from The Cancer Genome Atlas (TCGA) database.
Dali Yan +7 more
openaire +2 more sources
Functional Characterization of the Bladder Cancer Marker, BLCA-4 [PDF]
Clinical Cancer Research, 2004 Abstract Introduction: Bladder cancer is a common disease of the genitourinary tract for which the development of a noninvasive detection technique would have a significant impact on disease management. One of our previously identified bladder cancer-specific proteins, BLCA-4, appears to be associated with a “field effect” of the disease,
Thu-Suong, Van Le +4 more
openaire +2 more sources
A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA
BioMed Research International, 2022 Background. Bladder cancer (BLCA) is one of the most common urological malignancies globally, posing a severe threat to public health. In combination with protein‐protein interaction (PPI) network analysis of proteomics, Gene Set Variation Analysis (GSVA) and “CancerSubtypes” package of R software for transcriptomics can help identify biomarkers ...
Hanwen Li, Shaohua Chen, Hua Mi
openaire +2 more sources
Frontiers in Immunology, 2023 RationaleRNA modifications, containing m6A, m1A, alternative polyadenylation and adenosine-to-inosine RNA editing, involve in critical cancerous immunity and cancerous processes. However, the functional roles of RNA modification writers in bladder cancer
Yao Zhang, Ying Chen, Wen Wen
doaj +1 more source
Mechanistic Analysis of the Role of BLCA-4 in Bladder Cancer Pathobiology [PDF]
Cancer Research, 2005 Abstract Analysis of alterations in nuclear structure associated with bladder cancer has revealed specific changes associated with the disease. This includes the identification of six bladder cancer-specific proteins and the successful development of urine-based immunoassays for the detection of two of these biomarkers, BLCA-1 and BLCA-4.
Julie M, Myers-Irvin +2 more
openaire +2 more sources
Cancer Cell International, 2021 Background Bladder cancer (BLCA) is the most common genitourinary tumor but lacks specific diagnostic biomarkers. Recent years have witnessed significant advances in the use and approval of immune checkpoint blockade (ICB) therapy to manage BLCA at ...
YiHeng Du +7 more
doaj +1 more source
Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]
, 2017 Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick +9 more
core +2 more sources