Results 21 to 30 of about 13,979 (215)
Mechanistic Analysis of the Role of BLCA-4 in Bladder Cancer Pathobiology [PDF]
Cancer Research, 2005 Abstract Analysis of alterations in nuclear structure associated with bladder cancer has revealed specific changes associated with the disease. This includes the identification of six bladder cancer-specific proteins and the successful development of urine-based immunoassays for the detection of two of these biomarkers, BLCA-1 and ...
Julie M, Myers-Irvin +2 more
openaire +2 more sources
, 2021 Sample metadata information for TCGA-BLCA samples used in CSV format. (CSV)
Siddharth Jain (267351) +3 more
core +1 more source
The Relationship of Pyroptosis-Related Genes, Patient Outcomes, and Tumor-Infiltrating Cells in Bladder Urothelial Carcinoma (BLCA) [PDF]
, 2022 Introduction: The role of pyroptosis and its effects on tumor-infiltrating cells (TICs) in the pathogenesis and treatment outcomes of patients with bladder urothelial carcinoma (BLCA) remains unclear.Methods: We conducted a bioinformatics analysis on the
Ming Xie +5 more
core +1 more source
A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA
BioMed Research International, 2022 Background. Bladder cancer (BLCA) is one of the most common urological malignancies globally, posing a severe threat to public health. In combination with protein‐protein interaction (PPI) network analysis of proteomics, Gene Set Variation Analysis (GSVA) and “CancerSubtypes” package of R software for transcriptomics can help identify biomarkers ...
Hanwen Li, Shaohua Chen, Hua Mi
openaire +2 more sources
Frontiers in Immunology, 2023 RationaleRNA modifications, containing m6A, m1A, alternative polyadenylation and adenosine-to-inosine RNA editing, involve in critical cancerous immunity and cancerous processes. However, the functional roles of RNA modification writers in bladder cancer
Yao Zhang, Ying Chen, Wen Wen
doaj +1 more source
Journal of Cellular and Molecular Medicine, 2023 AbstractRecently, epigenetics showed essential roles in tumour microenvironment (TME) and immunotherapy response, however, the functions of RNA 5‐methylcytosine (m5C) modification in TME remains unknown. According to 13 m5C regulators, we evaluated 412 BLCA patients from The Cancer Genome Atlas (TCGA) database.
Dali Yan +7 more
openaire +2 more sources
Cancer Cell International, 2021 Background Bladder cancer (BLCA) is the most common genitourinary tumor but lacks specific diagnostic biomarkers. Recent years have witnessed significant advances in the use and approval of immune checkpoint blockade (ICB) therapy to manage BLCA at ...
YiHeng Du +7 more
doaj +1 more source
Journal of Inflammation Research, 2022 Mingde Gao1 *, Qiuxing Yang2 *, Haifei Xu,1 Zhigang Chen,1 Xiaolin Wang,1 Haifeng Guo1 1Department of Urology, Affiliated Tumor Hospital of Nantong University & Nantong Tumor Hospital, Nantong, 226361, People’s Republic of China; 2Department of ...
Gao M +5 more
doaj
Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms
BMC Cancer, 2019 Background The prognosis of bladder urothelial carcinoma (BLCA) varies greatly among patients, and conventional pathological predictors are generally inadequate and often inaccurate to predict the heterogeneous behavior of BLCA.
Shuxiong Zeng +11 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundPre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival. However, the predictive value and biological function of PRPF19 in bladder urothelial carcinoma (BLCA)
YaXuan Wang +7 more
doaj +1 more source