Results 21 to 30 of about 12,929 (204)

Deubiquitylase USP52 Promotes Bladder Cancer Progression by Modulating Ferroptosis through Stabilizing SLC7A11/xCT [PDF]

Advanced Science
Bladder cancer (BLCA) is a prevalent cancer with high case‐fatality rates and a substantial economic burden worldwide. Understanding its molecular underpinnings to guide clinical management is crucial. Ferroptosis, a recently described non‐apoptotic form
Jianmin Liu, Yongwen Luo, Siming Chen, Gang Wang, Wan Jin, Wenyu Jiang, Mingxing Li, Yejinpeng Wang, Jingtian Yu, Houyi Wei, Renjie Zhang, Fenfang Zhou, Lingao Ju, Yi Zhang, Yu Xiao, Kaiyu Qian, Xinghuan Wang   +16 more
doaj   +2 more sources

TAZ/NRF2 positive feedback loop contributes to proliferation in bladder cancer through antagonistic ferroptosis [PDF]

Cell Death Discovery
Bladder cancer (BLCA) is a prevalent malignancy characterized by high recurrence and metastasis rates. Emerging evidence suggests that the NRF2-GPX4 axis is closely associated with ferroptosis. The transcriptional coactivator with PDZ-binding motif (TAZ)
Zhen Song, Shikai Gui, Xuepeng Rao, Gan Zhang, Yu Cheng, Tao Zeng   +5 more
doaj   +2 more sources

Performance of 18F-FDG PET/MRI and its parameters in staging and neoadjuvant therapy response evaluation in bladder cancer [PDF]

iScience
Summary: 18F-FDG PET/MRI shows potential efficacy in the diagnosis of bladder cancer (BLCA). However, the performance of 18F-FDG PET/MRI in staging and neoadjuvant therapy (NAT) response evaluation for BLCA patients remains elusive. Here, we conduct this
Tianhang Li, Qinqin You, Shiwei Zhang, Rushuai Li, Shangxun Xie, Danyan Li, Shuyue Ai, Rong Yang, Hongqian Guo   +8 more
doaj   +2 more sources

TCGA-BLCA. [PDF]

, 2021
Sample metadata information for TCGA-BLCA samples used in CSV format. (CSV)
Siddharth Jain (267351), Jehoshua Bruck (6309647), Netanel Raviv (11408504), Bijan Mazaheri (11408501)   +3 more
core   +1 more source

Functional Characterization of the Bladder Cancer Marker, BLCA-4 [PDF]

Clinical Cancer Research, 2004
Abstract Introduction: Bladder cancer is a common disease of the genitourinary tract for which the development of a noninvasive detection technique would have a significant impact on disease management. One of our previously identified bladder cancer-specific proteins, BLCA-4, appears to be associated with a “field effect” of the ...
Thu-Suong, Van Le, Julie, Myers, Badrinath R, Konety, Timothy, Barder, Robert H, Getzenberg   +4 more
openaire   +2 more sources

The Relationship of Pyroptosis-Related Genes, Patient Outcomes, and Tumor-Infiltrating Cells in Bladder Urothelial Carcinoma (BLCA) [PDF]

, 2022
Introduction: The role of pyroptosis and its effects on tumor-infiltrating cells (TICs) in the pathogenesis and treatment outcomes of patients with bladder urothelial carcinoma (BLCA) remains unclear.Methods: We conducted a bioinformatics analysis on the
Ming Xie, Desmond Y. H. Yap, Litong Zhu, Wayne Lam, Ruiyan Xie, Joanne W. Y. Chiu   +5 more
core   +1 more source

Image1_The Relationship of Pyroptosis-Related Genes, Patient Outcomes, and Tumor-Infiltrating Cells in Bladder Urothelial Carcinoma (BLCA).TIF [PDF]

, 2022
Introduction: The role of pyroptosis and its effects on tumor-infiltrating cells (TICs) in the pathogenesis and treatment outcomes of patients with bladder urothelial carcinoma (BLCA) remains unclear.Methods: We conducted a bioinformatics analysis on the
Litong Zhu (6578963), Ming Xie (420493), Joanne W. Y. Chiu (13115742), Wayne Lam (355299), Desmond Y. H. Yap (13115745), Ruiyan Xie (13115739)   +5 more
core   +1 more source

Mechanistic Analysis of the Role of BLCA-4 in Bladder Cancer Pathobiology [PDF]

Cancer Research, 2005
Abstract Analysis of alterations in nuclear structure associated with bladder cancer has revealed specific changes associated with the disease. This includes the identification of six bladder cancer-specific proteins and the successful development of urine-based immunoassays for the detection of two of these biomarkers, BLCA-1 and ...
Julie M, Myers-Irvin, Thu-Suong, Van Le, Robert H, Getzenberg   +2 more
openaire   +2 more sources

A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA

BioMed Research International, 2022
Background. Bladder cancer (BLCA) is one of the most common urological malignancies globally, posing a severe threat to public health. In combination with protein‐protein interaction (PPI) network analysis of proteomics, Gene Set Variation Analysis (GSVA) and “CancerSubtypes” package of R software for transcriptomics can help identify biomarkers ...
Hanwen Li, Shaohua Chen, Hua Mi
openaire   +2 more sources

TCGA Bladder Urothelial Carcinoma (BLCA) Clinical Data [PDF]

, 2023
<p><strong>Abstract:</strong></p> <p>The Cancer Genome Atlas (TCGA) was a large-scale collaborative project initiated by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI). It aimed
Swati Baskiyar
core   +1 more source