Results 21 to 30 of about 15,721 (211)
Journal of Cellular and Molecular Medicine, 2023 AbstractRecently, epigenetics showed essential roles in tumour microenvironment (TME) and immunotherapy response, however, the functions of RNA 5‐methylcytosine (m5C) modification in TME remains unknown. According to 13 m5C regulators, we evaluated 412 BLCA patients from The Cancer Genome Atlas (TCGA) database.
Dali Yan +7 more
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Typing tumors using pathways selected by somatic evolution. [PDF]
, 2018 Many recent efforts to analyze cancer genomes involve aggregation of mutations within reference maps of molecular pathways and protein networks. Here, we find these pathway studies are impeded by molecular interactions that are functionally irrelevant to
Huang, Justin +6 more
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SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering [PDF]
, 2015 Background: With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available.
Fierro Gutierrez, Ana Carolina Elisa +3 more
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Journal of Inflammation Research, 2022 Mingde Gao1 *, Qiuxing Yang2 *, Haifei Xu,1 Zhigang Chen,1 Xiaolin Wang,1 Haifeng Guo1 1Department of Urology, Affiliated Tumor Hospital of Nantong University & Nantong Tumor Hospital, Nantong, 226361, People’s Republic of China; 2Department of ...
Gao M +5 more
doaj
Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms
BMC Cancer, 2019 Background The prognosis of bladder urothelial carcinoma (BLCA) varies greatly among patients, and conventional pathological predictors are generally inadequate and often inaccurate to predict the heterogeneous behavior of BLCA.
Shuxiong Zeng +11 more
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Metabolites, 2022 Bladder Cancer (BLCA) is the ninth most frequently diagnosed cancer globally and the sixth most common cancer in the US. African Americans (AA) exhibit half the BLCA incidence compared to European Americans (EA), but they have a 70% higher risk of cancer-
Karthik Reddy Kami Reddy +8 more
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The role of the BLCA-4 nuclear matrix protein in bladder cancer
Postępy Higieny i Medycyny Doświadczalnej, 2017 Bladder cancer (BC) affects usually older people. According to information provided by the National Cancer Registry in 2012. BC was the 4th, in terms of illness, cancer in men and 11th in women. Early diagnosis of bladder cancer is important because detected later has worse prognosis.Diagnosis of bladder cancer is not simple and it is still very ...
Beata, Szymańska, Anna, Długosz
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Frontiers in Immunology, 2023 BackgroundPre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival. However, the predictive value and biological function of PRPF19 in bladder urothelial carcinoma (BLCA)
YaXuan Wang +7 more
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Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types [PDF]
, 2018 Hotspot mutations in splicing factor genes have been recently reported at high frequency in hematological malignancies, suggesting the importance of RNA splicing in cancer.
Alvaro, Domenico +12 more
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Identification of autophagy‐related genes signature predicts chemotherapeutic and immunotherapeutic efficiency in bladder cancer (BLCA) [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractAutophagy maintains cellular homeostasis by degrading and recycling cytoplasmic components under stress conditions, which is identified to be involved in tumorigenesis and now has been recognized as novel target in cancer treatment. In present study, we gathered total autophagy‐related genes and established an autophagy‐related genes signature (
Rui Cao +5 more
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