Results 11 to 20 of about 13,979 (215)

The role of the BLCA-4 nuclear matrix protein in bladder cancer

Postępy Higieny i Medycyny Doświadczalnej, 2017
Bladder cancer (BC) affects usually older people. According to information provided by the National Cancer Registry in 2012. BC was the 4th, in terms of illness, cancer in men and 11th in women. Early diagnosis of bladder cancer is important because detected later has worse prognosis.Diagnosis of bladder cancer is not simple and it is still very ...
Beata, Szymańska, Anna, Długosz
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HYAL3 as a potential novel marker of BLCA patient prognosis

BMC Genomic Data, 2022
Background It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA.
Jun-peng Liu, Yu-tong Fang, Yi-fan Jiang, Hao Lin   +3 more
doaj   +3 more sources

Identification of FLRT2 as a key prognostic gene through a comprehensive analysis of TMB and IRGPs in BLCA patients [PDF]

Frontiers in Oncology
IntroductionThe tumor immune environment and immune-related genes are instrumental in the development, progression, and prognosis of bladder cancer (BLCA). This study sought to pinpoint key immune-related genes influencing BLCA prognosis and decipher their mechanisms of action.Methods and resultsWe analyzed differentially expressed genes (DEGs) between
Yaling Tao, Yaling Tao, Xiaoling Yu, Huaiwei Cong, Jinpeng Li, Jinpeng Li, Junqi Zhu, Huaxin Ding, Qian Chen, Qian Chen, Qian Chen, Ting Cai, Ting Cai   +12 more
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Immunohistochemical characterisation of the monoclonal antibody BLCA-38 for the detection of prostate cancer

Cancer Immunology, Immunotherapy, 2004
Monoclonal antibodies (MAbs) can be used to detect, image and treat cancers. This study aimed to characterise the binding of BLCA-38 MAbs to human prostate cancer cell lines, human prostate cancer biopsy samples and normal tissues to enable future targeted studies.BLCA-38 antigen expression on cancer lines was determined by flow cytometry; that on ...
P J, Russell, K T, Ow, P N, Tam, J, Juarez, E A, Kingsley, C F, Qu, Y, Li, P J, Cozzi, R, Martiniello-Wilks   +8 more
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Development of a prognostic model to predict BLCA based on anoikis-related gene signature: preliminary findings

BMC Urology, 2023
Abstract Background The prevalence of bladder urothelial carcinoma (BLCA) is significant on a global scale. Anoikis is a type of procedural cell death that has an important role in tumor invasion and metastasis. The advent of single-cell RNA sequencing (scRNA-seq) approaches has revolutionized the genomics field by ...
Shusheng Zhu, Qingsong Zhao, Yanpeng Fan, Chao Tang   +3 more
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Apoptosis related genes mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide immunotherapy in bladder cancer

BMC Medical Genomics, 2023
Apoptosis has been discovered as a mechanism of cell death. The purpose of this study is to identify the diagnostic signature factors related to bladder cancer (BLCA) through apoptosis related genes (ARGs).
Liquan Zhou, Guanglong Xu, Fu Huang, Wenyuan Chen, Jiange Zhang, Yong Tang   +5 more
doaj   +2 more sources

Performance of 18F-FDG PET/MRI and its parameters in staging and neoadjuvant therapy response evaluation in bladder cancer

iScience
Summary: 18F-FDG PET/MRI shows potential efficacy in the diagnosis of bladder cancer (BLCA). However, the performance of 18F-FDG PET/MRI in staging and neoadjuvant therapy (NAT) response evaluation for BLCA patients remains elusive. Here, we conduct this
Tianhang Li, Qinqin You, Shiwei Zhang, Rushuai Li, Shangxun Xie, Danyan Li, Shuyue Ai, Rong Yang, Hongqian Guo   +8 more
doaj   +2 more sources

BLCA-RegMap portal: a co-regulatory influence network view of bladder cancer heterogeneity

, 2022
International audienceIntroduction: Bladder cancer studies performed in a variety of laboratories and by anumber of large-scale projects have given an unparalleled amount of information on tumors and in vitro models.
Pawlak, Geoffrey, Dispot, Aurélien, Puig, Julia, Elati, Mohamed, Dhifli, Wajdi   +4 more
core   +5 more sources

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase-Dependent K48-Linked Degradation of PTRF. [PDF]

Cancer Sci
Schematic model of TRIM59‐driven BLCA progression through K48‐linked ubiquitination and proteasomal degradation of PTRF, leading to AKT activation and c‐Myc upregulation. ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood ...
Gan J, Bai X, Zhang A, Lin F, Tong H, Li T, Xu N, Li X, Yu Z, Yin H.   +9 more
europepmc   +2 more sources

Functional Characterization of the Bladder Cancer Marker, BLCA-4 [PDF]

Clinical Cancer Research, 2004
Abstract Introduction: Bladder cancer is a common disease of the genitourinary tract for which the development of a noninvasive detection technique would have a significant impact on disease management. One of our previously identified bladder cancer-specific proteins, BLCA-4, appears to be associated with a “field effect” of the ...
Thu-Suong, Van Le, Julie, Myers, Badrinath R, Konety, Timothy, Barder, Robert H, Getzenberg   +4 more
openaire   +2 more sources