Results 11 to 20 of about 15,721 (211)

HYAL3 as a potential novel marker of BLCA patient prognosis

open access: yesBMC Genomic Data, 2022
Background It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA.
Jun-peng Liu   +3 more
doaj   +3 more sources

Functional Characterization of the Bladder Cancer Marker, BLCA-4 [PDF]

open access: yesClinical Cancer Research, 2004
Abstract Introduction: Bladder cancer is a common disease of the genitourinary tract for which the development of a noninvasive detection technique would have a significant impact on disease management. One of our previously identified bladder cancer-specific proteins, BLCA-4, appears to be associated with a “field effect” of the ...
Thu-Suong, Van Le   +4 more
openaire   +2 more sources

Mechanistic Analysis of the Role of BLCA-4 in Bladder Cancer Pathobiology [PDF]

open access: yesCancer Research, 2005
Abstract Analysis of alterations in nuclear structure associated with bladder cancer has revealed specific changes associated with the disease. This includes the identification of six bladder cancer-specific proteins and the successful development of urine-based immunoassays for the detection of two of these biomarkers, BLCA-1 and ...
Julie M, Myers-Irvin   +2 more
openaire   +2 more sources

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +6 more sources

A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA

open access: yesBioMed Research International, 2022
Background. Bladder cancer (BLCA) is one of the most common urological malignancies globally, posing a severe threat to public health. In combination with protein‐protein interaction (PPI) network analysis of proteomics, Gene Set Variation Analysis (GSVA) and “CancerSubtypes” package of R software for transcriptomics can help identify biomarkers ...
Hanwen Li, Shaohua Chen, Hua Mi
openaire   +2 more sources

Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]

open access: yes, 2017
Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick   +9 more
core   +2 more sources

Comprehensive analysis of CXCL12 expression reveals the significance of inflammatory fibroblasts in bladder cancer carcinogenesis and progression

open access: yesCancer Cell International, 2021
Background Bladder cancer (BLCA) is the most common genitourinary tumor but lacks specific diagnostic biomarkers. Recent years have witnessed significant advances in the use and approval of immune checkpoint blockade (ICB) therapy to manage BLCA at ...
YiHeng Du   +7 more
doaj   +1 more source

Four types of adenine-related RNA modification writers -mediated molecular subtypes contribute to predicting clinical outcomes and treatment options in bladder cancer

open access: yesFrontiers in Immunology, 2023
RationaleRNA modifications, containing m6A, m1A, alternative polyadenylation and adenosine-to-inosine RNA editing, involve in critical cancerous immunity and cancerous processes. However, the functional roles of RNA modification writers in bladder cancer
Yao Zhang, Ying Chen, Wen Wen
doaj   +1 more source

Pancancer analysis of DNA methylation-driven genes using MethylMix. [PDF]

open access: yes, 2015
Aberrant DNA methylation is an important mechanism that contributes to oncogenesis. Yet, few algorithms exist that exploit this vast dataset to identify hypo- and hypermethylated genes in cancer.
Gevaert, Olivier   +2 more
core   +2 more sources

Identification of a basement membrane-related genes signature with immune correlation in bladder urothelial carcinoma and verification in vitro

open access: yesBMC Cancer, 2023
Background Bladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies of basement membrane-related genes (BM-related genes) in BLCA are less reported.
Yanze Li   +8 more
doaj   +1 more source

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