The role of the BLCA-4 nuclear matrix protein in bladder cancer [PDF]
Postępy Higieny i Medycyny Doświadczalnej, 2017 Bladder cancer (BC) affects usually older people. According to information provided by the National Cancer Registry in 2012. BC was the 4th, in terms of illness, cancer in men and 11th in women. Early diagnosis of bladder cancer is important because detected later has worse prognosis.Diagnosis of bladder cancer is not simple and it is still very ...
Beata, Szymańska, Anna, Długosz
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Development of a prognostic model to predict BLCA based on anoikis-related gene signature: preliminary findings [PDF]
BMC Urology, 2023 Abstract Background The prevalence of bladder urothelial carcinoma (BLCA) is significant on a global scale. Anoikis is a type of procedural cell death that has an important role in tumor invasion and metastasis. The advent of single-cell RNA sequencing (scRNA-seq) approaches has revolutionized the genomics field by ...
Shusheng Zhu +3 more
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Identification of a basement membrane-related genes signature with immune correlation in bladder urothelial carcinoma and verification in vitro [PDF]
BMC Cancer, 2023 Background Bladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies of basement membrane-related genes (BM-related genes) in BLCA are less reported.
Yanze Li +8 more
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HYAL3 as a potential novel marker of BLCA patient prognosis
BMC Genomic Data, 2022 Background It has been previously demonstrated that hyaluronan (HA) potentially regulates the initiation and propagation of bladder cancer (BLCA). HYAL3 encodes hyaluronidase and is a potential therapeutic target for BLCA.
Jun-peng Liu +3 more
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Identification of FLRT2 as a key prognostic gene through a comprehensive analysis of TMB and IRGPs in BLCA patients [PDF]
Frontiers in OncologyIntroductionThe tumor immune environment and immune-related genes are instrumental in the development, progression, and prognosis of bladder cancer (BLCA). This study sought to pinpoint key immune-related genes influencing BLCA prognosis and decipher their mechanisms of action.Methods and resultsWe analyzed differentially expressed genes (DEGs) between
Yaling Tao +12 more
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Identification of Immune-Related Subtypes and Construction of a Novel Prognostic Model for Bladder Urothelial Cancer [PDF]
Biomolecules, 2022 The purpose of this study was to explore the relationship between bladder urothelial cancer (BLCA) and immunity, to screen prognosis-related immune genes (PIGs), and to construct an immune-related prognosis model (IRPM). We processed the relevant data of
Jiange Zhang +8 more
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BLCA-RegMap portal: a co-regulatory influence network view of bladder cancer heterogeneity [PDF]
, 2022 Introduction: Bladder cancer studies performed in a variety of laboratories and by anumber of large-scale projects have given an unparalleled amount of information on tumors and in vitro models. Consolidating these data into an easily accessible and comprehensive system-level format is crucial to accelerate systems oncology model development.Methods ...
Pawlak, Geoffrey +4 more
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Prognostic value of LncRNA DLGAP1-AS2 in bladder cancer and its regulatory effect on tumor progression [PDF]
Discover OncologyBackground Bladder cancer (BLCA) represents one of the most prevalent malignant neoplasms within the urinary system, and its incidence is progressively rising annually in China.
Yuhui Zhao +7 more
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Menin facilitates the cell proliferation of bladder cancer via modulating the TFAP2C/β-catenin axis [PDF]
Genes and DiseasesBladder cancer (BLCA) is a common malignant tumor of the urinary system, with significant morbidity and mortality rates worldwide. The MEN1 gene, encoding the menin protein, plays a regulatory role in several cancers. However, the role played by menin in
Qing Shi +9 more
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Comprehensive analysis of PRPF19 immune infiltrates, DNA methylation, senescence-associated secretory phenotype and ceRNA network in bladder cancer [PDF]
Frontiers in Immunology, 2023 BackgroundPre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival. However, the predictive value and biological function of PRPF19 in bladder urothelial carcinoma (BLCA)
YaXuan Wang +7 more
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