Results 21 to 30 of about 15,201 (184)

Identification of a basement membrane-related genes signature with immune correlation in bladder urothelial carcinoma and verification in vitro

open access: yesBMC Cancer, 2023
Background Bladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies of basement membrane-related genes (BM-related genes) in BLCA are less reported.
Yanze Li   +8 more
doaj   +1 more source

Identification of Immune-Related Subtypes and Construction of a Novel Prognostic Model for Bladder Urothelial Cancer

open access: yesBiomolecules, 2022
The purpose of this study was to explore the relationship between bladder urothelial cancer (BLCA) and immunity, to screen prognosis-related immune genes (PIGs), and to construct an immune-related prognosis model (IRPM). We processed the relevant data of
Jiange Zhang   +8 more
doaj   +1 more source

Pancancer analysis of DNA methylation-driven genes using MethylMix. [PDF]

open access: yes, 2015
Aberrant DNA methylation is an important mechanism that contributes to oncogenesis. Yet, few algorithms exist that exploit this vast dataset to identify hypo- and hypermethylated genes in cancer.
Gevaert, Olivier   +2 more
core   +2 more sources

Typing tumors using pathways selected by somatic evolution. [PDF]

open access: yes, 2018
Many recent efforts to analyze cancer genomes involve aggregation of mutations within reference maps of molecular pathways and protein networks. Here, we find these pathway studies are impeded by molecular interactions that are functionally irrelevant to
Huang, Justin   +6 more
core   +3 more sources

BLCA prognostic model creation and validation based on immune gene-metabolic gene combination

open access: yesDiscover Oncology, 2023
Abstract Background Bladder cancer (BLCA) is a prevalent urinary system malignancy. Understanding the interplay of immunological and metabolic genes in BLCA is crucial for prognosis and treatment. Methods Immune/metabolism genes were extracted, their expression profiles ...
Shao-Yu Yue   +9 more
openaire   +3 more sources

Identification of autophagy‐related genes signature predicts chemotherapeutic and immunotherapeutic efficiency in bladder cancer (BLCA) [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2021
AbstractAutophagy maintains cellular homeostasis by degrading and recycling cytoplasmic components under stress conditions, which is identified to be involved in tumorigenesis and now has been recognized as novel target in cancer treatment. In present study, we gathered total autophagy‐related genes and established an autophagy‐related genes signature (
Rui Cao   +5 more
openaire   +2 more sources

SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering [PDF]

open access: yes, 2015
Background: With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available.
Fierro Gutierrez, Ana Carolina Elisa   +3 more
core   +2 more sources

Small nucleolar RNAs signature (SNORS) identified clinical outcome and prognosis of bladder cancer (BLCA) [PDF]

open access: yesCancer Cell International, 2020
Abstract Background Small nucleolar RNAs (snoRNAs) are a new non-coding RNAs (ncRNAs), which have not been widely investigated and are identified to be involved in tumorigenesis. But the function of snoRNAs in BLCA has not been reported yet. Methods SnoRNAs signature (SNORS)
Rui Cao   +4 more
openaire   +3 more sources

Lipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer

open access: yesMetabolites, 2022
Bladder Cancer (BLCA) is the ninth most frequently diagnosed cancer globally and the sixth most common cancer in the US. African Americans (AA) exhibit half the BLCA incidence compared to European Americans (EA), but they have a 70% higher risk of cancer-
Karthik Reddy Kami Reddy   +8 more
doaj   +1 more source

Preoperative White Blood Cell-Related Indicators Can Predict the Prognosis of Patients with Transurethral Resection of Bladder Cancer

open access: yesJournal of Inflammation Research, 2022
Mingde Gao1 *, Qiuxing Yang2 *, Haifei Xu,1 Zhigang Chen,1 Xiaolin Wang,1 Haifeng Guo1 1Department of Urology, Affiliated Tumor Hospital of Nantong University & Nantong Tumor Hospital, Nantong, 226361, People’s Republic of China; 2Department of ...
Gao M   +5 more
doaj  

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