Results 21 to 30 of about 15,495 (203)

SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy

open access: yesCell Division, 2023
Background Nucleosome-localized sirtuin 4 (SIRT4) was found to function as an oncogene and tumor suppressor gene in different tumors. However, the clinical significance of SIRT4 in bladder urothelial carcinoma (BLCA) has not been assessed, nor has the ...
Jie Yin   +5 more
doaj   +1 more source

AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma

open access: yesFrontiers in Pharmacology, 2022
A large proportion of bladder cancer (BLCA) patients suffer from malignant progression to life-threatening muscle-invasive bladder cancer (MIBC). Inflammation is a critical event in cancer development, but little is known about the role of inflammation ...
Houhong Zhou   +10 more
doaj   +1 more source

Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway

open access: yesCancer Cell International, 2022
Background Bladder cancer (BLCA) is one of the most common malignancies worldwide. One of the main reasons for the unsatisfactory management of BLCA is the complex molecular biological mechanism.
Piao Li   +10 more
doaj   +1 more source

A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA

open access: yesBioMed Research International, 2022
Background. Bladder cancer (BLCA) is one of the most common urological malignancies globally, posing a severe threat to public health. In combination with protein‐protein interaction (PPI) network analysis of proteomics, Gene Set Variation Analysis (GSVA) and “CancerSubtypes” package of R software for transcriptomics can help identify biomarkers ...
Hanwen Li, Shaohua Chen, Hua Mi
openaire   +2 more sources

NUPR1 imparts oncogenic potential in bladder cancer

open access: yesCancer Medicine, 2023
Background NUPR1, or p8, is a small chromatin protein that plays a central role in the resistance to treatment and progression of cancer. Nevertheless, the molecular mechanism of NUPR1 in bladder cancer (BLCA) remains unclear.
Lifeng Zhang   +7 more
doaj   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +6 more sources

Mechanistic Analysis of the Role of BLCA-4 in Bladder Cancer Pathobiology [PDF]

open access: yesCancer Research, 2005
Abstract Analysis of alterations in nuclear structure associated with bladder cancer has revealed specific changes associated with the disease. This includes the identification of six bladder cancer-specific proteins and the successful development of urine-based immunoassays for the detection of two of these biomarkers, BLCA-1 and BLCA-4.
Julie M, Myers-Irvin   +2 more
openaire   +2 more sources

Identification of a basement membrane-related genes signature with immune correlation in bladder urothelial carcinoma and verification in vitro

open access: yesBMC Cancer, 2023
Background Bladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies of basement membrane-related genes (BM-related genes) in BLCA are less reported.
Yanze Li   +8 more
doaj   +1 more source

Identification of Immune-Related Subtypes and Construction of a Novel Prognostic Model for Bladder Urothelial Cancer

open access: yesBiomolecules, 2022
The purpose of this study was to explore the relationship between bladder urothelial cancer (BLCA) and immunity, to screen prognosis-related immune genes (PIGs), and to construct an immune-related prognosis model (IRPM). We processed the relevant data of
Jiange Zhang   +8 more
doaj   +1 more source

Four types of adenine-related RNA modification writers -mediated molecular subtypes contribute to predicting clinical outcomes and treatment options in bladder cancer

open access: yesFrontiers in Immunology, 2023
RationaleRNA modifications, containing m6A, m1A, alternative polyadenylation and adenosine-to-inosine RNA editing, involve in critical cancerous immunity and cancerous processes. However, the functional roles of RNA modification writers in bladder cancer
Yao Zhang, Ying Chen, Wen Wen
doaj   +1 more source

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