Results 91 to 100 of about 53,368 (224)
Malignant craniopharyngiomas: Institutional experience and literature review
Brain Pathology, Volume 36, Issue 4, July 2026.We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source
, 2006 Vascular malformations are errors of the vascular morphogenesis. Depending on the dominating vessel of the lesion, we can describe several types of malformations: capillary, venous, arterial, lymphatic and mixed.
Tatulescu, D, Secheli, M, Secheli, I
core
Liver International, Volume 46, Issue 7, July 2026.ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley +1 more source
KIRA7 reverses bleomycin-induced fibrosis when given 2 weeks after bleomycin exposure.
, 2019 (A) Schematic of the KIRA7 reversal regimen. Mice were exposed to saline or bleomycin once, then treated with KIRA7 or vehicle beginning two weeks after bleomycin exposure and continuing daily for two additional weeks.
Bradley J. Backes (2495482) +9 more
core +1 more source
S100A4 Orchestrates Fibroblast Fate to Drive Fibrotic Remodeling
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Fibrotic stimuli induce S100A4 expression, promoting the activation of apoptosis‐resistant fibroblasts through engagement of ERK‐associated signaling. In fibroblasts, S100A4 orchestrates fibroblast fate by enhancing migration, promoting stress fiber formation, increasing ECM contractility, upregulating α‐SMA expression, and supporting survival ...
Spring Li +6 more
wiley +1 more source
Augmentation of bleomycin-induced DNA damage in intact cells
, 1989 Bleomycin, an important cause of pulmonary fibrosis, is known to produce DNA damage. The mechanism for this damage in vitro is related to free radical production by a bleomycin and iron complex. To determine whether bleomycin causes damage to DNA in vivo
P. L. Moseley
core +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source