Results 91 to 100 of about 97,876 (294)

Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review

The Laryngoscope, EarlyView.
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff, Logan F. McColl, Robert A. Baiocchi, Matthew O. Old   +3 more
wiley   +1 more source

Synergistic effect of Achillea millefolium L. combined with bleomycin on prostate cancer cell

Research in Molecular Medicine, 2015
Background: The aim of this study was to investigate the effect of methanolic extract of Achillea millefolium L. (MEA) on the antiproliferative activity of bleomycin on human prostate cancer and normal skin cells.
Somayeh Shahani, Negar Hamzekanlu, Neda Zakeri, Seyed Jalal Hosseinimehr   +3 more
doaj  

Bleomycin induced flagellate erythema in a patient with thalamic mixed germ cell tumour: Report of a rare adverse effect

Journal of the Egyptian National Cancer Institute, 2016
Bleomycin induced flagellate dermatitis is an uncommon and unique adverse effect. With the declining use of bleomycin, this complication is becoming increasingly infrequent in day-to-day clinical practice.
Ahitagni Biswas, Pramod Kumar Julka
doaj   +1 more source

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages [PDF]

, 2017
Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the DNA damage response (DDR) kinases ATM and DNA-PKcs through the generation of double stranded ...
Akira, Akira, Alaoui-El-Azher, Amiri, Anand, Bakkenist, Bednarski, Bednarski, Blunt, Bredemeyer, Bredemeyer, Callen, Callén, Chatzinikolaou, Chumduri, Ciccia, Clausen, Cuevas-Ramos, Edelson, Erttmann, Fedor, Floyd, Frank, Frisan, Griffith, Guerra, Guo, Helmink, Helmink, Herrtwich, Hsieh, Huang, Innes, Jackson, Jinadasa, Karo, Kraal, Kuziel, Lamkanfi, Laubach, Lilley, MacMicking, McNab, Mosser, Nathan, Nesić, Nirodi, Nougayrède, Nunes, Okamura, Pollock, Radi, Ritchie, Rogakou, Roth, Rouleau, Schoenborn, Schwab, Sekiguchi, Sherman, Shi, Tamir, Theunissen, von Moltke, Weitzman, Witte, Wu, Zha   +67 more
core   +3 more sources

Endoscopic Suture Ligation and Sclerotherapy for Pharyngolaryngeal Venous Malformation

The Laryngoscope, EarlyView.
This study evaluated suture ligation combined with sclerotherapy in 53 patients with pharyngolaryngeal venous malformations. A single procedure achieved complete resolution in 79.25% of cases, with no serious complications or need for prophylactic tracheostomy.
Jiajun Tian, Juke Ma, Ahmad A. Hariri, Zhenghua Lv, Peng Cui, Wei Xu   +5 more
wiley   +1 more source

Bioanalytical method development and validation of bleomycin sulphate

Journal of Applied Pharmaceutical Research, 2017
Bleomycin is an anti-neoplastic drug that has recently been used for the treatment of vascular anomalies. An expedient method was developed for the determination of plasma bleomycin levels using ion-paired reversed phase high performance liquid ...
Yash Prashar, Harkaran Singh Rana, Souravh Bais   +2 more
doaj  

Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.

PLoS Genetics, 2013
Pulmonary fibrosis is a disease of significant morbidity, with no effective therapeutics and an as yet incompletely defined genetic basis. The chemotherapeutic agent bleomycin induces pulmonary fibrosis in susceptible C57BL/6J mice but not in mice of the
Anguel N Stefanov, Jessica Fox, François Depault, Christina K Haston   +3 more
doaj   +1 more source

Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro. [PDF]

, 2011
OBJECTIVE: The origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through ...
Jimenez, Sergio A., Li, zhaodong
core   +2 more sources

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, Hai‐Ying Mary Cheng, Michael A. Laflamme, Hai‐Ling Margaret Cheng   +12 more
wiley   +1 more source

The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats

Pulmonary Medicine, 2016
The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats. Twenty-four Wistar rats randomly divided into four groups (control, bleomycin alone, bleomycin + naringin 40, and bleomycin
Nergiz H. Turgut, Haki Kara, Sahende Elagoz, Koksal Deveci, Huseyin Gungor, Emre Arslanbas   +5 more
doaj   +1 more source