Results 101 to 110 of about 62,115 (257)
PLoS Genetics, 2013 Pulmonary fibrosis is a disease of significant morbidity, with no effective therapeutics and an as yet incompletely defined genetic basis. The chemotherapeutic agent bleomycin induces pulmonary fibrosis in susceptible C57BL/6J mice but not in mice of the
Anguel N Stefanov +3 more
doaj +1 more source
Distribution of bleomycin in a rat model
, 2000 Bleomycin has, in the years of developing electrochemotherapy (ECT), proven to be an extremely potent drug for this cancer treatment modality and is also the most frequently applied chemical agent.
Engström, P +9 more
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.TGF‐β1 increases DNMT1?mediated SOCS3 promoter hypermethylation to repress SOCS3 expression. Loss of SOCS3‐dependent inhibition de‐represses JAK2‐STAT3 signaling and drives abnormal activation of vocal fold fibroblasts, contributing to vocal fold fibrosis. ABSTRACT Objective To investigate the effect of TGF‐β1 on vocal fold fibroblasts (VFFs) phenotype
Hai‐Zhou Wang +4 more
wiley +1 more source
Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7
Yeast, EarlyView.ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley +1 more source
Dermatology Practical & Conceptual, 2017 Background: Numerous studies have been performed to evaluate the efficacy of intralesional bleomycin for the treatment of warts with inconsistent result.
Paola Pasquali +4 more
doaj +1 more source
, 1976 Results from treating 51 patients with advanced esophageal cancer are presented. Fifteen patients were treated with Bleomycin, 12 with radiotherapy, and 24 with a combination of Bleomycin and radiotherapy.
Ivo Dujmović +3 more
core +1 more source
Oxygen metabolite detoxifying enzyme levels in bleomycin-induced fibrotic lungs [PDF]
, 1988 The activities of three enzymes cytosolic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSHP), and malonylialdehyde (MDA), a by-product of lipid peroxidation, were determined in whole lungs of normal and bleomycin-treated rats ...
Phan, Sem H., Fantone, Joseph C.
core +1 more source
Interventional oncology in children: Where are we now?
Journal of Medical Imaging and Radiation Oncology, EarlyView.Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel +1 more
wiley +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
Andrology, EarlyView.ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Radiation Doses 51Cr-Bleomycin
, 1987 Extensive studies were made of long-term whole-body retention, plasma concentration, urinary excretion and organ retention of 51Cr in rats after intravenous injection of 51Cr-bleomycin. A similar but less extensive investigation was performed on rabbits,
J. Greger +4 more
core +1 more source