Results 81 to 90 of about 97,876 (294)

Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment [PDF]

, 2015
The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential.
F. Rizzo, G. Leter, GALLO, MARIAGRAZIA, GANDINI, Loredana, LENZI, Andrea, LOMBARDO, Francesco, M. Spano, PAOLI, Donatella   +7 more
core   +1 more source

Hodgkin lymphoma of the ampulla of Vater: A rare cause of obstructive jaundice in children

JPGN Reports, EarlyView.
Abstract Hodgkin lymphoma (HL) has a wide spectrum of presentation. Most cases affect lymph nodes (nodal), while extranodal involvement is rare. Whereas the gastrointestinal tract is enriched with lymphoid tissues, the ampulla of Vater is not rich in lymphoid tissue. Involvement of the ampulla of Vater with HL has rarely been reported in adults and has
Sultana Alshammari, Homoud Alhebbi, Awad Al Qahtani, Sarah Algubaisi, Faisal Alhaffaf, Abdulrahman Al Robayan, Mohammed Almutairi, Saeed Alshieban, Mohammad Alshahrani, Tarek Khaled Alfawzan, Khalid Alkhamis, Ibrahim Al Hasan, Sami Wali   +12 more
wiley   +1 more source

Characterization of acute lung injury in the bleomycin rat model

Physiological Reports, 2023
The aim of this study was to describe and characterize the pathophysiological changes occurring during the early inflammatory phase (first 3 days) in the rat bleomycin model of lung injury preceding the development of fibrosis.
Anil Hari Kadam, Jan E. Schnitzer
doaj   +1 more source

Modelling single cell electroporation with bipolar pulse parameters and dynamic pore radii [PDF]

, 2010
We develop a model of single spherical cell electroporation and simulate spatial and temporal aspects of the transmembrane potential and pore radii as an effect of any form of applied electric field.
Cree, Michael J., Gaynor, Paul, Talele, Sadhana, van Ekeran, Jethro   +3 more
core   +2 more sources

A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. [PDF]

, 2020
Alveolar formation increases the surface area for gas-exchange and is key to the physiological function of the lung. Alveolar epithelial cells, myofibroblasts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary
Chou, Yu-Ting, Chuang, Pao-Tien, Li, Jianying, Lin, Chuwen, Wolters, Paul J, Wong, Julia, Yao, Erica, Zhang, Kuan   +7 more
core   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

Respiratory Research, 2005
Background In the present study, by comparing the responses in wild-type mice (WT) and mice lacking (KO) the inducible (or type 2) nitric oxide synthase (iNOS), we investigated the role played by iNOS in the development of on the lung injury caused by ...
Crimi Nunzio, Gili Elisa, Frasca Giuseppina, Sortino Maria, Mazzon Emanuela, Failla Marco, Di Paola Rosanna, Cuzzocrea Salvatore, Genovese Tiziana, Caputi Achille P, Vancheri Carlo   +10 more
doaj   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Long-term results of pleurodesis in malignant pleural effusions: Doxycycline vs Bleomycin

Advanced Biomedical Research, 2014
Background: The aim of this study was to compare the response of doxycycline and bleomycin in pleurodesis of malignant pleural effusions. Materials and Methods: The radiologic and clinical responses of doxycycline and bleomycin in pleurodesis of ...
Rahmatollah Rafiei, Behnam Yazdani, Sayed Milad Ranjbar, Zahra Torabi, Sedigheh Asgary, Somayeh Najafi, Mahtab Keshvari   +6 more
doaj   +1 more source

Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO [PDF]

, 2001
A prospective, multicenter, randomized trial was undertaken to compare the efficacy and toxicity of adriamycin with mitoxantrone within a 6-drug combination chemotherapy regimen for elderly patients (older than 60 years) with high-grade non-Hodgkin ...
Cunningham, D., Gregory, W., Hancock, B., Hoskin, P., Hudson, G.V., Linch, D., MacLennan, K., Mainwaring, P.N., Norton, A.J., Smith, P.   +9 more
core   +1 more source