Results 81 to 90 of about 1,389,504 (295)

Contiguous temporal withholding for hemispheric analysis in frontal EEG during cycling

open access: yesMethodsX
We present a methodological framework for evaluating temporal sensitivity in frontal EEG recordings during cycling. The approach departs from randomized train–test splits and instead implements contiguous temporal withholding to preserve physiological ...
Roberto Carlos Hernández-del-Valle   +2 more
doaj   +1 more source

A Tight Lower Bound on Certificate Complexity in Terms of Block Sensitivity and Sensitivity [PDF]

open access: yes, 2014
Sensitivity, certificate complexity and block sensitivity are widely used Boolean function complexity measures. A longstanding open problem, proposed by Nisan and Szegedy, is whether sensitivity and block sensitivity are polynomially related. Motivated by the constructions of functions which achieve the largest known separations, we study the relation ...
Andris Ambainis, Krisjanis Prksis
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Haloperidol blocks the acquisition but not the retrieval of a conditioned sensitization to apomorphine [PDF]

open access: yesBehavioural Pharmacology, 2003
The dopamine agonist apomorphine (apo) elicits stereotyped pecking bouts in pigeons, a response which increases with successive apo injections. The present study sought, first, to confirm the hypothesis that this sensitization arises through a Pavlovian conditioning driven by both external and internal cues; and, secondly, to advance the hypothesis ...
Acerbo, Martin J.   +2 more
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Stabilization and control system power sensitivity study [PDF]

open access: yes
Stabilization and control system sensitivity to power-off failure rate studied by simulated missions using block power ...
Clemmens, W. C.   +5 more
core   +1 more source

Stochastic Evaluation of Parameters Variability on a Terminated Signal Bus [PDF]

open access: yes, 2011
This paper addresses the simulation of the effects on a high-speed data link of external factors due to fabrication tolerances or uncertain loading conditions.
Canavero, Flavio   +2 more
core  

A Utility Proportional Fairness Radio Resource Block Allocation in Cellular Networks

open access: yes, 2014
This paper presents a radio resource block allocation optimization problem for cellular communications systems with users running delay-tolerant and real-time applications, generating elastic and inelastic traffic on the network and being modelled as ...
Abdelhadi, Ahmed   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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