Results 321 to 330 of about 966,153 (399)

Spatiotemporal Angiogenic Patterns in the Development of the Mouse Fetal Blood-Brain Barrier System During Pregnancy. [PDF]

Int J Mol Sci
Brown SN, Shallie P, Sierra CA, Nayak N, Odibo AO, Monaghan-Nichols P, Nayak NR.   +6 more
europepmc   +1 more source

Difluoromethylornithine Decreases Postischemic Brain Edema and Blood-Brain Barrier Breakdown

, 1993
Marcus P. Schmitz, David J. Combs, Robert J. Dempsey   +2 more
openalex   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

Advanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu, Ming Yi, Ji Chen, Jing Zhang, Xiaobin Ma, Xiaojun Zhang, Liang Zeng, Yan Xue, Haimei Wen, Yujiao Deng, Pengfei Zhou, Kongming Wu, Huafeng Kang, Zhijun Dai   +13 more
wiley   +1 more source

Advances in brain-targeted delivery strategies and natural product-mediated enhancement of blood-brain barrier permeability. [PDF]

J Nanobiotechnology
Liu S, Jin X, Ge Y, Dong J, Liu X, Pei X, Wang P, Wang B, Chang Y, Yu XA.   +9 more
europepmc   +1 more source

Immunolocalization of Heat Shock Protein after Fluid Percussive Brain Injury and Relationship to Breakdown of the Blood-Brain Barrier

, 1993
Hirokazu Tanno, Russ P. Nockels, Lawrence H. Pitts, Linda J. Noble‐Haeusslein   +3 more
openalex   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion. [PDF]

CNS Neurosci Ther
Nie Q, Zhang L, Gu Z, Li Y, Bi X.
europepmc   +1 more source

Kinetic Analysis of the Human Blood-Brain Barrier Transport of Lactate and its Influence by Hypercapnia

, 1991
Gitte M. Knudsen, Olaf B. Paulson, Marianne M. Hertz   +2 more
openalex   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier. [PDF]

Fluids Barriers CNS
Szecskó A, Mészáros M, Simões B, Cavaco M, Chaparro C, Porkoláb G, Castanho MARB, Deli MA, Neves V, Veszelka S.   +9 more
europepmc   +1 more source