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The Blood-Brain Barrier in Psychosis
Blood-brain barrier pathology is recognised as a central factor in the development of many neurological disorders, but much less is known about the role of the blood-brain barrier in psychiatric disorders.
Thomas A Pollak +11 more
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Differentiation of the brain vasculature : the answer came blowing by the Wnt [PDF]
Vascularization of the vertebrate brain takes place during embryonic development from a preformed perineural vascular plexus. As a consequence of the intimate contact with neuroectodermal cells the vessels, which are entering the brain exclusively via ...
Liebner, Stefan +3 more
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Blood-Brain Barrier Genomics [PDF]
Blood-brain barrier (BBB) genomics begins with the isolation of capillaries from fresh animal or human brain and is followed on the same day with the purification of capillary-derived RNA. The identification of microvascular-enriched genes from a whole brain gene microarray is unlikely because the brain capillary endothelial volume is <0.1% of total
openaire +2 more sources
Brain-Penetrating Peptide Shuttles Across the Blood-Brain Barrier and Extracellular-like Space [PDF]
Here, we describe a combinatorial approach to identify peptide shuttles that successfully traverse the multiple barriers to systemic drug delivery to the brain--1. the blood-brain barrier (BBB) and the 2.
Yen-Liang, Liu +9 more
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Laminins and the blood-brain barrier
The blood-brain barrier (BBB) is a dynamic structure that maintains brain homeostasis. BBB breakdown is a key pathological hallmark of almost all neurological diseases. Although the regulation of BBB integrity by different cells has been extensively studied, the function of its non-cellular component-the basal lamina in BBB regulation remains largely ...
Ava Nasrollahi, Yao Yao
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Adipokines and the blood-brain barrier [PDF]
Just as the blood-brain barrier (BBB) is not a static barrier, the adipocytes are not inert storage depots. Adipokines are peptides or polypeptides produced by white adipose tissue; they play important roles in normal physiology as well as in the metabolic syndrome. Adipokines secreted into the circulation can interact with the BBB and exert potent CNS
Weihong, Pan, Abba J, Kastin
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Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]
Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Karsten Schöller +9 more
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Regional variation in the current flow across an insect blood-brain barrier
One notable characteristic of the insect and vertebrate central nervous system is the presence of a clearly defined blood-brain barrier. In the insect this barrier is made up of the perineurial glial cells, and shows a heterogeneity in structure and ...
Smith, P.J., Shipley, A.
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β1-integrin/matrix interactions support blood-brain barrier integrity
Brain microvascular endothelium forms an active permeability barrier, the blood-brain barrier (BBB). In neurologic disorders, barrier properties of the BBB are often lost indicating their dependance on molecular cues of the brain microenvironment.
Engelhardt, Britta, Britta Engelhardt
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What is the difference between the blood–nerve barrier and blood–brain barrier? [PDF]
application/pdfThe blood–brain barrier and blood–nerve barrier play crucial roles in maintaining homeostasis of the central and peripheral nervous systems. Takeshita et al.
Nakatsuji, Yuji, Yuji Nakatsuji
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