Results 31 to 40 of about 4,745,742 (154)

The Blood-Brain Barrier in Psychosis

open access: yes, 2018
Blood-brain barrier pathology is recognised as a central factor in the development of many neurological disorders, but much less is known about the role of the blood-brain barrier in psychiatric disorders.
Thomas A Pollak   +11 more
core   +1 more source

Differentiation of the brain vasculature : the answer came blowing by the Wnt [PDF]

open access: yes, 2010
Vascularization of the vertebrate brain takes place during embryonic development from a preformed perineural vascular plexus. As a consequence of the intimate contact with neuroectodermal cells the vessels, which are entering the brain exclusively via ...
Liebner, Stefan   +3 more
core   +1 more source

Blood-Brain Barrier Genomics [PDF]

open access: yesStroke, 2007
Blood-brain barrier (BBB) genomics begins with the isolation of capillaries from fresh animal or human brain and is followed on the same day with the purification of capillary-derived RNA. The identification of microvascular-enriched genes from a whole brain gene microarray is unlikely because the brain capillary endothelial volume is <0.1% of total
openaire   +2 more sources

Brain-Penetrating Peptide Shuttles Across the Blood-Brain Barrier and Extracellular-like Space [PDF]

open access: yes, 2019
Here, we describe a combinatorial approach to identify peptide shuttles that successfully traverse the multiple barriers to systemic drug delivery to the brain--1. the blood-brain barrier (BBB) and the 2.
Yen-Liang, Liu   +9 more
core   +1 more source

Laminins and the blood-brain barrier

open access: yesMatrix Biology
The blood-brain barrier (BBB) is a dynamic structure that maintains brain homeostasis. BBB breakdown is a key pathological hallmark of almost all neurological diseases. Although the regulation of BBB integrity by different cells has been extensively studied, the function of its non-cellular component-the basal lamina in BBB regulation remains largely ...
Ava Nasrollahi, Yao Yao
openaire   +2 more sources

Adipokines and the blood-brain barrier [PDF]

open access: yesPeptides, 2007
Just as the blood-brain barrier (BBB) is not a static barrier, the adipocytes are not inert storage depots. Adipokines are peptides or polypeptides produced by white adipose tissue; they play important roles in normal physiology as well as in the metabolic syndrome. Adipokines secreted into the circulation can interact with the BBB and exert potent CNS
Weihong, Pan, Abba J, Kastin
openaire   +2 more sources

Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]

open access: yes, 2011
Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Karsten Schöller   +9 more
core   +1 more source

Regional variation in the current flow across an insect blood-brain barrier

open access: yes, 1990
One notable characteristic of the insect and vertebrate central nervous system is the presence of a clearly defined blood-brain barrier. In the insect this barrier is made up of the perineurial glial cells, and shows a heterogeneity in structure and ...
Smith, P.J., Shipley, A.
core   +1 more source

β1-integrin/matrix interactions support blood-brain barrier integrity

open access: yes, 2011
Brain microvascular endothelium forms an active permeability barrier, the blood-brain barrier (BBB). In neurologic disorders, barrier properties of the BBB are often lost indicating their dependance on molecular cues of the brain microenvironment.
Engelhardt, Britta, Britta Engelhardt
core   +1 more source

What is the difference between the blood–nerve barrier and blood–brain barrier? [PDF]

open access: yes, 2017
application/pdfThe blood–brain barrier and blood–nerve barrier play crucial roles in maintaining homeostasis of the central and peripheral nervous systems. Takeshita et al.
Nakatsuji, Yuji, Yuji Nakatsuji
core   +1 more source

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