Results 181 to 190 of about 80,969 (285)

Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier. [PDF]

Fluids Barriers CNS
Zhao T, Pellegrini L, van der Hee B, Boekhorst J, Fernandes A, Brugman S, van Baarlen P, Wells JM.   +7 more
europepmc   +1 more source

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source

VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier. [PDF]

Nat Commun
Martikainen M, Lugano R, Pietilä I, Brosch S, Cabrolier C, Sivaramakrishnan A, Ramachandran M, Yu D, Dimberg A, Essand M.   +9 more
europepmc   +1 more source

Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain

Exploration, EarlyView.
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li, Ye Wang, Guangyu Jia, Yamei Yu, Zhe Zhang, Qi Wang, Kaelyn V. Becker, Jonathan W. Engle, Dawei Jiang, Weibo Cai   +9 more
wiley   +1 more source

Breast-to-brain metastasis is exacerbated with chemotherapy through blood-cerebrospinal fluid barrier and induces Alzheimer's-like pathology. [PDF]

J Neurosci Res, 2023
Saatian B, Deshpande K, Herrera R, Sedighi S, Eisenbarth R, Iyer M, Das D, Julian A, Martirosian V, Lowman A, LaViolette P, Remsik J, Boire A, Sankey E, Fecci PE, Shiroishi MS, Chow F, Hurth K, Neman J.   +18 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives. [PDF]

Hum Cell
Schwerk C, Schroten H.
europepmc   +1 more source

Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse. [PDF]

Fluids Barriers CNS, 2022
Kung Y, Chen KY, Liao WH, Hsu YH, Wu CH, Hsiao MY, Huang AP, Chen WS.   +7 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Advances in Intrathecal Nanoparticle Delivery: Targeting the Blood-Cerebrospinal Fluid Barrier for Enhanced CNS Drug Delivery. [PDF]

Pharmaceuticals (Basel)
Madadi AK, Sohn MJ.
europepmc   +1 more source