Results 171 to 180 of about 80,969 (285)

Expression and Functional Evaluation of ABC and SLC Transporters in Human Choroid Plexus Papilloma (HIBCPP) Cells: A Human Blood-Cerebrospinal Fluid Barrier Model. [PDF]

Pharm Res
Kurosawa T, Ohtsuki S, Ishikawa H, Schroten H, Schwerk C, Kubo Y, Deguchi Y.   +6 more
europepmc   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Relationship between blood-cerebrospinal fluid barrier integrity, cardiometabolic, and inflammatory factors in schizophrenia-spectrum disorders. [PDF]

Brain Behav Immun Health
Yakimov V, Jäger I, Roell L, Boudriot E, Meisinger V, Campana M, Krčmář L, Halstead S, Warren N, Siskind D, Maurus I, Hasan A, Falkai P, Schmitt A, Raabe FJ, Keeser D, CDP-Working Group, Wagner E, Moussiopoulou J.   +18 more
europepmc   +1 more source

A Novel Method for the Determination of Vitamin D Metabolites Assessed at the Blood-Cerebrospinal Fluid Barrier. [PDF]

Biomolecules, 2021
Zelzer S, Meinitzer A, Herrmann M, Goessler W, Enko D.   +4 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Hyphal penetration is the major pathway of translocation of Candida albicans across the blood-cerebrospinal fluid barrier. [PDF]

Fluids Barriers CNS
Schmidt S, Schwerk C, Schroten H, Ishikawa H, Schubert R, Lehrnbecher T, Rudolph H.   +6 more
europepmc   +1 more source

Live Tissue Imaging Reveals Distinct Transcellular Pathways for Organic Cations and Anions at the Blood-Cerebrospinal Fluid Barrier. [PDF]

Mol Pharmacol, 2022
Hu T, Zha W, Sun A, Wang J.
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Transcriptome and Functional Comparison of Primary and Immortalized Endothelial Cells of the Human Choroid Plexus at the Blood-Cerebrospinal Fluid Barrier. [PDF]

Int J Mol Sci
Denzer L, Muranyi W, Herold R, Stump-Guthier C, Ishikawa H, Sticht C, Schroten H, Schwerk C, Weichert S.   +8 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source