Results 1 to 10 of about 340,580 (305)

Plasmatic and cell-based enhancement by microparticles originated from platelets and endothelial cells under simulated in vitro conditions of a dilutional coagulopathy

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background Aggressive fluid management and other external factors may lead to hypothermia, acidosis and hemodilution (defined as Lethal Triad, LT) contributing to a trauma-induced coagulopathy (TIC) that worsens patients’ outcomes.
Julia K. Böhm, Nadine Schäfer, Marc Maegele, Birgit Stümpges, Ursula Bauerfeind, Michael Caspers   +5 more
doaj   +1 more source

Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter season [PDF]

, 2010
Background and Objective Air temperature changes are associated with increased cardiovascular and respiratory risk, but the roles of inflammatory and coagulation markers are not well understood.
Breitner, Susanne, Frampton, Mark W., Hampel, Regina, Koenig, Wolfgang, Peters, Annette, Phipps, Richard P., Rückerl, Regina, Schneider, Alexandra, Wichmann, Heinz-Erich   +8 more
core   +1 more source

It Is Written in the Clot: Coagulation Assessment in Severe Burn Injury

European Burn Journal
Background: Coagulopathy in severe burn injury is associated with complications and mortality. Methods: We compared 3 tests (EXTEM, INTEM, FIBTEM) of rotational thromboelastometry (ROTEM), a viscoelastic coagulation assay (VCA), with conventional ...
Eirini Nikolaidou, Andriana Lazaridou, Christina Iasonidou, Alexandra Tsaroucha, Sophia Papadopoulou, Eleni Kaldoudi, Apostolos Sovatzidis, Despoina Kakagia   +7 more
doaj   +1 more source

Changes in Blood Viscosity With Synthetic Protease Inhibitors

Journal of Pharmacological Sciences, 2003
We examined the effects on whole blood viscosity and coagulation time of various dosages of the synthetic low-molecular protease inhibitors gabexate mesilate and nafamostat mesilate with an oscillation-type viscometer.
Masahito Hitosugi, Munehiro Niwa, Tomoyoshi Takahashi, Akira Kurosu, Hirohisa Nihei, Toshiaki Nagai, Shogo Tokudome   +6 more
doaj   +1 more source

In Vitro Antithrombotic, Hematological Toxicity, and Inhibitor Studies of Protocatechuic, Isovanillic, and p-Hydroxybenzoic Acids from Maclura tricuspidata (Carr.) Bur

Molecules, 2022
In blood coagulation, circulating platelets and coagulation factors are crucial for the primary process because thrombi are generated by fibrin clotting with fibrinogen, thrombin, FXIIIa, and platelet activation.
Jun-Hui Choi, Seung Kim
doaj   +1 more source

The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]

, 2017
Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo, Liumbruno, Giancarlo M., Marano, Giuseppe, Marietta, Marco, Mengoli, Carlo, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

THE REGULATORY ROLE OF COAGULATION FACTORS ON ARTERIAL FUNCTION

Artery Research, 2018
The coagulation takes place in the physiological system of hemostasis. Hemostasis is known to be disturbed in many diseases leading to hemorrhages or thrombosis.
Jeremy Lagrange
doaj   +1 more source

Responses of some blood coagulation factors in recovery period after interval and continuous efforts for swimmers [PDF]

مجلة الرافدين للعلوم الرياضية, 2012
تحددت مشكلة البحث في دراسة استجابات بعض عوامل تخثر الدم في فترة استعادة الشفاء بعد الجهدين الفتري والمستمر لدى السباحين. وهدف البحث إلى الكشف عن استجابات بعض عوامل تخثر الدم في فترة الاستشفاء بعد الجهد الفتري والمستمر وفي فترة الاستشفاء(1) ساعة بعد ...
Nashwan I. Abdullah
doaj   +1 more source

Fluorescence artifact correction in the thrombin generation assay: Necessity for correction algorithms in procoagulant samples

Research and Practice in Thrombosis and Haemostasis, 2021
Introduction The thrombin generation (TG) test is a global hemostasis assay sensitive to procoagulant conditions. However, some TG assays may underestimate elevated TG when the thrombin fluorogenic substrate is depleted or fluorescence is attenuated by ...
William C. Chang, Joseph W. Jackson, Kellie R. Machlus, Alisa S. Wolberg, Mikhail V. Ovanesov   +4 more
doaj   +1 more source

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]

, 2003
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike, Engelmann, Bernd, Klocke, Antje, Kotzsch, Matthias, Luther, Thomas, Morgenstern, Eberhard, Müller, Ingrid, Preissner, Klaus, Zahler, Stefan, Zieseniss, Susanne   +9 more
core   +1 more source