Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]
Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA+5 more
core +1 more source
Molar substitution and C2/C6 ratio of hydroxyethyl starch: influence on blood coagulation [PDF]
Background. Development of hydroxyethyl starches (HES) with a low impact on blood coagulation but a long intravascular persistence is of clinical interest.
Bombeli, T.+7 more
core
Integrated Optofluidic Sensor for Coagulation Risk Monitoring in COVID-19 Patients at Point-of-Care [PDF]
While the pathophysiology underlying the COVID-19 infection remains incompletely understood, there is growing evidence to indicate that it is closely correlated to hypercoagulation among severely ill patients. Doctors may choose for use anti-coagulation doses to treat the patients at intensive care units. A rapid, easy, and low-cost solution to monitor
arxiv
Inhibited Coagulation of Micron-size Dust Due to the Electrostatic Barrier [PDF]
The collisional evolution of solid material in protoplanetary disks is a crucial step in the formation of planetesimals, comets, and planets. Although dense protoplanetary environments favor fast dust coagulation, there are several factors that limit the straightforward pathway from interstellar micron-size grains to pebble-size aggregates.
arxiv +1 more source
The role of neutrophil extracellular traps in thrombosis
According to the cellular model of hemostasis, the process of blood coagulation is presented in the form of three phases: initiation, amplification and propagation, each of them includes several consecutive stages. At the same time, thrombus formation is
S.M. Chooklin, S.S. Chuklin
doaj +1 more source
Koagulasi Intravasa Diseminata [PDF]
Suhardi D. A. &A. H. Asdie - Disseminated intravascular coagulation Bleeding may result from abnormalities\u27 of platelet, blood vessel walls, or coagulation.
Suhardi D. A dan Ahmad H. Asdie
core +1 more source
A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams+158 more
core +1 more source
Shear-induced unfolding and enzymatic cleavage of full-length VWF multimers [PDF]
Proteolysis of the multimeric blood coagulation protein von Willebrand Factor (VWF) by ADAMTS13 is crucial for prevention of microvascular thrombosis. ADAMTS13 cleaves VWF within the mechanosensitive A2 domain, which is believed to open under shear flow.
arxiv +1 more source
Surface functionalization-specific binding of coagulation factors by zinc oxide nanoparticles delays coagulation time and reduces thrombin generation potential in vitro. [PDF]
Zinc oxide nanoparticles (ZnO NPs) have many biomedical applications such as chemotherapy agents, vaccine adjuvants, and biosensors but its hemocompatibility is still poorly understood, especially in the event of direct contact of NPs with blood ...
Jun-Young Yang+11 more
doaj +1 more source
The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes [PDF]
Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce ...
Brunel, Helena+7 more
core +4 more sources