Results 61 to 70 of about 1,225,419 (385)

Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage

open access: yesEBioMedicine, 2022
Summary: Background: Neuroinflammation and blood coagulation responses in cerebrospinal fluid (CSF) contribute to the poor outcome associated with subarachnoid haemorrhage (SAH).
Yuanjian Fang   +13 more
doaj  

Propensity score adjusted comparison of three-factor versus four-factor prothrombin complex concentrate for emergent warfarin reversal: a retrospective cohort study

open access: yesBMC Emergency Medicine, 2020
Background Prothrombin Complex Concentrates (PCC) are prescribed for emergent warfarin reversal (EWR). The comparative effectiveness and safety among PCC products are not fully understood.
David J. Margraf   +5 more
doaj   +1 more source

Effects of hemoglobin-based oxygen carriers on blood coagulation. [PDF]

open access: yes, 2014
For many decades, Hemoglobin-based oxygen carriers (HBOCs) have been central in the development of resuscitation agents that might provide oxygen delivery in addition to simple volume expansion.
Holtby, Randall J   +2 more
core   +3 more sources

Blood coagulation factor VIII: An overview

open access: yesJournal of Biosciences, 2003
Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be ...
G. M. Bhopale, Rabindra K. Nanda
openaire   +2 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Integrated Optofluidic Sensor for Coagulation Risk Monitoring in COVID-19 Patients at Point-of-Care [PDF]

open access: yesarXiv, 2020
While the pathophysiology underlying the COVID-19 infection remains incompletely understood, there is growing evidence to indicate that it is closely correlated to hypercoagulation among severely ill patients. Doctors may choose for use anti-coagulation doses to treat the patients at intensive care units. A rapid, easy, and low-cost solution to monitor
arxiv  

Inhibited Coagulation of Micron-size Dust Due to the Electrostatic Barrier [PDF]

open access: yes, 2020
The collisional evolution of solid material in protoplanetary disks is a crucial step in the formation of planetesimals, comets, and planets. Although dense protoplanetary environments favor fast dust coagulation, there are several factors that limit the straightforward pathway from interstellar micron-size grains to pebble-size aggregates.
arxiv   +1 more source

Koagulasi Intravasa Diseminata [PDF]

open access: yes, 1991
Suhardi D. A. &A. H. Asdie - Disseminated intravascular coagulation Bleeding may result from abnormalities\u27 of platelet, blood vessel walls, or coagulation.
Suhardi D. A dan Ahmad H. Asdie
core   +1 more source

Binding of human blood-coagulation Factors IXa and X to phospholipid membranes.

open access: yesBiochemical Journal, 1984
A simple centrifugation technique has been developed to study the interaction of human coagulation Factors IXa and X with phospholipid membranes. In the presence of Ca2+, equimolar phosphatidylserine/phosphatidylcholine membranes form tight complexes ...
K. Mertens   +3 more
semanticscholar   +1 more source

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