Determination of volume, shape and refractive index of individual blood platelets [PDF]
Light scattering patterns (LSP) of blood platelets were theoretically and experimentally analyzed. We used spicular spheroids as a model for the platelets with pseudopodia. The discrete dipole approximation was employed to simulate light scattering from an individual spicular spheroid constructed from a homogeneous oblate spheroid and 14 rectilinear ...
arxiv +1 more source
Palabos-npFEM: Software for the Simulation of Cellular Blood Flow (Digital Blood) [PDF]
Palabos-npFEM is a computational framework for the simulation of blood flow with fully resolved constituents. The software resolves the trajectories and deformed state of blood cells, such as red blood cells and platelets, and the complex interaction between them. The tool combines the lattice Boltzmann solver Palabos for the simulation of blood plasma
arxiv +1 more source
Background. In our previously published studies, we demonstrated a high hemostatic activity of a low dose of exogenous fibrin monomer during its systemic administration in a model of dosed liver injury with preliminary inhibition of platelet aggregation.
V. M. Vdovin+6 more
doaj +1 more source
Numerous studies indicate that the usage of natural compounds, such as those found in dandelion, might modulate blood platelets’ function. Our previous investigations indicated that fractions obtained from different organs of dandelion possessed anti ...
Bernadetta Lis+5 more
doaj
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian+79 more
core +2 more sources
von Willebrand Factor unfolding mediates platelet deposition in a model of high-shear thrombosis [PDF]
Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand Factor (vWF). vWF unfolds in response to strong flow gradients and facilitates rapid recruitment of platelets in flowing blood. While the thrombogenic effect of vWF is well recognized, its conformational response in complex flows has largely ...
arxiv +1 more source
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice [PDF]
Platelets play an essential role in hemostasis and atherothrombosis. Owing to their short storage time, there is constant demand for this life-saving blood component.
A Schmitt+53 more
core +2 more sources
PERBANDINGAN KADAR TROMBOSIT PADA DARAH VENA DAN KAPILER MENGGUNAKAN ANTIKOAGULAN K3EDTA [PDF]
Selection of the wrong type of examination sample can affect the results of the examination. Examination of blood cell counts can be taken from venous blood and capillary blood, but in capillary blood sampling there can be a dilution of the blood by ...
Franciscus Deni Suryatama+2 more
core +2 more sources
Platelet Physiology: In Cold Blood [PDF]
One of the impediments precluding long-term storage of platelets for blood transfusion is that refrigerated platelets are rapidly cleared from the circulation upon transfusion. New evidence suggests that this clearance is mediated in the liver by the Mac-1 integrin on Kupffer cells recognizing clustered GPIb receptor on platelets, leading to platelet ...
Michael C. Berndt, Robert K. Andrews
openaire +3 more sources
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source