Results 61 to 70 of about 4,701,486 (364)

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade.

Blood, 2015
Oxidized low-density lipoprotein (oxLDL) promotes unregulated platelet activation in dyslipidemic disorders. Although oxLDL stimulates activatory signaling, it is unclear how these events drive accelerated thrombosis.
S. Magwenzi, Casey Woodward, K. Wraith, A. Aburima, Z. Raslan, H. Jones, C. McNeil, S. Wheatcroft, N. Yuldasheva, M. Febbriao, M. Kearney, K. Naseem   +11 more
semanticscholar   +1 more source

Blood platelets and blood clotting [PDF]

Experimental Biology and Medicine, 1913
That the formed elements of the blood play a part in normal coagulation has long been known. Both leucocytes and platelets have been said to yield substances which contribute to fibrin formation. Leucocytes alone, however, will not coagulate fibrinogen.
openaire   +3 more sources

Regulating billions of blood platelets: glycans and beyond.

Blood, 2015
The human body produces and removes 10(11) platelets daily to maintain a normal steady state platelet count. Platelet production must be regulated to avoid spontaneous bleeding or arterial occlusion and organ damage.
Grozovsky R, Giannini S, Falet H, Hoffmeister KM.   +3 more
europepmc   +2 more sources

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]

, 2009
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian, Alexandra Mazharian, Arias-Salgado, Arias-Salgado, Arthur Weiss, Asselin, Auger, Avecilla, Baker, Best, Best, Cheli, Choudhuri, Dhanjal, Dorahy, Dubois, Ezumi, Gibbins, Gibbins, Harper, Hermiston, Holsinger, Jenson Lim, Jing W. Zhu, Jocelyn M. Auger, Kalia, Kato, Klages, Kovalenko, Kralisz, Kristin N. Kornerup, Le Pera, Lin, Lin, Liu, Mangin, McCarty, McNeill, Michael G. Tomlinson, Minuz, Moarefi, Mocsai, Morton, Neena Kalia, Nonne, Obergfell, Palka, Park, Pasquet, Pasquet, Pasquet, Pearce, Poole, Quek, Senis, Snell, Somani, Sorby, Steve G. Thomas, Steve P. Watson, Stuart Ellison, Superti-Furga, Suzuki-Inoue, Suzuki-Inoue, Tarvinder Dhanjal, Tsuboi, Vandendries, Wagner, Watanabe, Watson, Wonerow, Woodside, Xu, Xu, Yamaguchi, Yan Zhao, Yotis A. Senis, Young, Zhang, Zhu   +79 more
core   +2 more sources

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Anti-platelet activity of phytocompounds in various dandelion organs in human whole blood model in vitro

Journal of Functional Foods, 2021
Numerous studies indicate that the usage of natural compounds, such as those found in dandelion, might modulate blood platelets’ function. Our previous investigations indicated that fractions obtained from different organs of dandelion possessed anti ...
Bernadetta Lis, Joanna Rywaniak, Dariusz Jedrejek, Aleksandra Szustka, Anna Stochmal, Beata Olas   +5 more
doaj  

ABO Groups in Blood Platelets [PDF]

Nature, 1954
IT has been found that suspensions of blood platelets in normal saline are agglutinated by A- B- and O-sera, just as these sera agglutinate red blood cells of the corresponding blood group. It is thus possible to establish four blood groups for the blood platelets, similar to the blood groups in erythrocytes.
D. Nelken, J. Gurevitch
openaire   +5 more sources

Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer

OncoTarget, 2015
Purpose: Non-small-cell lung cancers harboring EML4-ALK rearrangements are sensitive to crizotinib. However, despite initial response, most patients will eventually relapse, and monitoring EML4-ALK rearrangements over the course of treatment may help ...
R. J. Nilsson, N. Karachaliou, J. Berenguer, -. AnaGimenez, Capitan, Pepijn Schellen, C. Teixidó, J. Tannous, J. Kuiper, E. Drees, M. Grabowska, M. Keulen, D. Heideman, E. Thunnissen, A. Dingemans, S. Viteri, A. Bakhos, Tannous, A. Drozdowskyj, R. Rosell, E. Smit, Thomas, Wurdinger   +22 more
semanticscholar   +1 more source

Analysis of platelet-rich plasma extraction variations in platelet and blood components between 4 common commercial kits [PDF]

, 2017
Background: Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP. Purpose:
Bulsara, MK, Fitzpatrick, J, McCrory, PR, Richardson, MD, Zheng, MH   +4 more
core   +2 more sources

New approaches to preparation and storage of platelets [PDF]

, 2012
During the last century, transfusion of blood components has become a prerequisite for treatment in many clinical settings. The availability of plastic bags and methods for centrifugation and separation of blood cells, has enabled processing of whole ...
Larsson, Stella
core   +1 more source