Results 111 to 120 of about 42,313 (282)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

KEANEKARAGAMAN INDOOR AIRBORNE MOLD DI PERPUSTAKAAN UNIVERSITAS GADJAH MADA DAN IDENTIFIKASI ISOLAT BLUE GREEN ASPERGILLI PEMBAWA GEN ALERGEN ASP F1 [PDF]

, 2013
The objective of this research was to 1) investigate the diversity of indoor airborne mold isolates are isolated from some libraries of the UGM based on morphological characteristic, (ii) detection of Asp f1 allergen gene of isolates blue green ...
, Prof. Drs. Langkah Sembiring, M.Sc., Ph.D., , RAHMAWATI   +1 more
core  

Ozone Treatment as a Sustainable Alternative for Suppressing Blue Mold in Mandarins and Extending Shelf Life [PDF]

Citrus fruits, particularly mandarins, are highly valued globally for their nutritional benefits and versatile culinary uses. However, the challenge of post-harvest decay, primarily due to blue mold (Penicillium italicum) infections, results in ...
Helena Viric Gasparic, Galešić, Marija Andrijana, Marija Andrijana Galešić, Mario Bjeliš, Darija Lemic, Lemić, Darija, Virić Gašparić, Helena, Bjeliš, Mario   +7 more
core   +1 more source

Induced defense responses and control of blue mold of apple fruit by Zaatar (Zataria multiflora) extract

Bihdāsht-i Mavādd-i Ghaz̠āyī
Blue mold, caused by Penicillium expansum, is considered one of the most serious postharvest diseases of apple fruits. This study was conducted to evaluate the efficacy of thyme methanol extract to control the postharvest blue mold of apple fruit and its ...
Pedram Alimosazadeh, Syed javad Sanei, Abdol Hossein Taheri   +2 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

First morpho-molecular identification of Penicillium griseofulvum and P. aurantiogriseum toxicogenic isolates associated with blue mold on apple. [PDF]

, 2010
Postharvest blue mold decay caused by Penicillium spp. is the most important disease of fresh apple fruit in the world, which extend from the field to the store. Two new Penicillium spp. responsible for apple fruit decay were recovered. The morphological
Moslem M.A., Bahkali A.H, Yassin M.A., Abd-Elsalam K.A   +3 more
core  

Studies on the green and blue mold of Satsuma orange (3)

Japanese Journal of Phytopathology, 1959
The growth stimulating effect of the contents of Satsuma orange fruit rind to Penicillium digitatum (green mold) and P. italicum (Blue mold) was studied.Extract from the orange rind by 80∼99.5% methanol or 80% acetone showed a promotive effect for the mycelial growth of both fungi. The growth stimulative substance was readily adsorbed by active carbon;
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Penicillium bialowiezense Causing Blue Mold on Bag-Cultivated Shiitake (Lentinula edodes) in China: Morphological, Molecular and Pathogenic Characterization

Horticulturae
Lentinula edodes (shiitake) is a major edible and medicinal mushroom and a key component of the horticultural mushroom industry in East Asia. During April–June 2024 cropping season, a widespread blue mold outbreak was observed on bag-cultivated shiitake ...
Tan Wang, Enping Zhou, Caixia Wang, Zhifeng Zhang, Yingjun Zhang, Siliang Huang, Qiuhong Niu   +6 more
doaj   +1 more source