Results 51 to 60 of about 2,067 (154)
Engineering Hybrid Polymeric Gd2O3 Nanoparticles for Tumor‐Targeted Neutron Capture Therapy
ChemNanoMat, Volume 12, Issue 4, April 2026.Neutron capture therapy (NCT) stands as a transformative approach for precision oncology. The principle relies on tumor‐targeted isotopes, such as boron‐10 (10B) and gadolinium‐157 (157Gd), for generating cytotoxic high energy particles upon thermal neutron irradiation.
Xiwen Chen +16 more
wiley +1 more source
Development of Measuring 10B Concentrations in Boron Neutron Capture Therapy
He huaxue yu fangshe huaxue, 2023 Boron neutron capture therapy(BNCT), as a highly promising radiotherapy modality, has emerged as a significant treatment option for various malignant tumors, including high-grade gliomas, recurrent head and neck cancers, and melanoma.
LI Lin +3 more
doaj +1 more source
Next‐Generation Electron Linear Accelerators for Compact Accelerator‐Driven Neutron Sources
Engineering Reports, Volume 8, Issue 3, March 2026.High‐gradient electron linear accelerators (linacs) enable cost‐effective, high‐performance compact accelerator‐driven neutron sources (CANSs) for industrial applications. Comparing with existing CANS, we show that high‐gradient linacs open a previously unexplored region of the CANS landscape, enabling accessible stress diffractometry with competitive ...
L. M. Wroe +4 more
wiley +1 more source
, 1991 This Bulletin presents a summary of accomplishments and highlights in the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Program for April 1991. This bulletin includes information on the brain tumor and melanoma research programs, Power Burst Facility (PBF) technical support and modifications, PBF operations, a ...
openaire +2 more sources
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta +14 more
wiley +1 more source
Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series
Life, 2022 Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem
Yi-Wei Chen +31 more
doaj +1 more source
Biology, 2023 Integrin αvβ3 is more highly expressed in high-grade glioma cells than in normal tissues. In this study, a novel boron-10 carrier containing maleimide-functionalized closo-dodecaborate (MID), serum albumin as a drug delivery system, and cyclic arginine ...
Kohei Tsujino +18 more
doaj +1 more source
PRELIMINARY MATHEMATICAL MODEL FOR CANCER TREATMENT USING BORON NEUTRON CANCER THERAPY (BNCT)
BarekengThis article outlines a revolutionary approach to immunotherapy and stem-cell cancer treatments that leverages Boron Neutron Cancer Therapy (BNCT). We formulated two models, one being the immunotherapy-BNCT model and the other featuring a stem-cell ...
Suryasatriya Trihandaru +5 more
doaj +1 more source
International Journal of Cancer, Volume 157, Issue 11, Page 2374-2384, 1 December 2025.What's New? Boron neutron capture therapy (BNCT) is a targeted form of radiation therapy designed to selectively destroy cancer cells. BNCT is not widely used, however, owing in part to challenges involving selective boron delivery to tumors. The present study evaluated the potential of a novel glucoconjugate, 6‐O‐(o‐carboranylmethyl)‐d‐glucopyranose ...
Surachet Imlimthan +15 more
wiley +1 more source