Results 51 to 60 of about 3,162 (145)

The neuropathology of fatal encephalomyelitis in human Borna virus infection [PDF]

, 2019
After many years of controversy, there is now recent and solid evidence that classical Borna disease virus 1 (BoDV-1) can infect humans. On the basis of six brain autopsies, we provide the first systematic overview on BoDV-1 tissue distribution and the ...
Angstwurm, Klemens, Beer, Martin, Brochhausen, Christoph, Ebinger, Arnt, Goehring, Lutz, Haschka, Stefan, Heckmann, Josef G., Hemmer, Bernhard, Herden, Christiane, Herms, Jochen, Jantsch, Jonathan, Kaletka, Gwendolyn, Lichtmannegger, Ines, Liesche, Friederike, Maerkl, Bruno, Matiasek, Kaspar, Neumann, Bernhard, Niller, Hans-Helmut, Permanetter, Willibald, Rieder, Georg, Riemenschneider, Markus J., Rosati, Marco, Rubbenstroth, Dennis, Ruf, Viktoria, Schlegel, Jürgen, Schlottau, Kore, Schmidt, Barbara, Wachter, Miguel Frederic, Wunderlich, Silke, Zoubaa, Saida   +29 more
core   +1 more source

Scientists identify more infections with classical Borna disease virus : Newly published study in „The Lancet Infectious Diseases“ provides insights into human infections with Borna Disease Virus (BoDV-1): FLI Press release 01/2020 [PDF]

, 2020
Insel Riems, 8 January 2020. The study published today in the renowned medical journal „The Lancet Infectious Diseases“ collects and characterizes known human infections with Borna Disease Virus (BoDV-1).

core   +4 more sources

Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

Viruses, 2022
Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that pose a
Nicolas Tarbouriech, Florian Chenavier, Junna Kawasaki, Kamel Bachiri, Jean-Marie Bourhis, Pierre Legrand, Lily L. Freslon, Estelle M. N. Laurent, Elsa Suberbielle, Rob W. H. Ruigrok, Keizo Tomonaga, Daniel Gonzalez-Dunia, Masayuki Horie, Etienne Coyaud, Thibaut Crépin   +14 more
doaj   +1 more source

Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report

BMC Infectious Diseases, 2021
Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Arnt Ebinger, Christiane Herden, Christoph Schulze, Birgit Muntau, Petra Eggert, Petra Allartz, Gerlind Schuldt, Jonas Schmidt-Chanasit, Martin Beer, Dennis Rubbenstroth   +13 more
doaj   +1 more source

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

Emerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann, Dennis Rubbenstroth, Daniel Cadar, Corinna Thomé-Bolduan, Petra Eggert, Alexander Schlaphof, Frank Leypoldt, Martin Stangel, Thorsten Fortwängler, Florian Hoffmann, Andreas Osterman, Sabine Zange, Hans-Helmut Niller, Klemens Angstwurm, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Martin Beer, Jonas Schmidt-Chanasit, Dennis Tappe   +19 more
doaj   +1 more source

Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

iScience, 2022
Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty, Luca Bettamin, Anne Thouard, Karine Bourgade, Sophie Allart, Guilhem Larrieu, Cécile Evelyne Malnou, Daniel Gonzalez-Dunia, Elsa Suberbielle   +8 more
doaj   +1 more source

Molecular epidemiology of human Borna disease virus 1 infection revisited

Emerging Microbes and Infections, 2022
Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
doaj   +1 more source

Detection of bornavirus-reactive antibodies and BoDV-1 RNA only in encephalitis patients from virus endemic areas: a comparative serological and molecular sensitivity, specificity, predictive value, and disease duration correlation study. [PDF]

Infection, 2023
Abstract Purpose Human Borna disease virus (BoDV-1) encephalitis is an emerging disease in Germany. This study investigates the spectrum of human BoDV-1 infection, characterizes anti-BoDV-1-antibodies and kinetics, and compares laboratory test performances.
Allartz P, Hotop SK, Muntau B, Schlaphof A, Thomé-Bolduan C, Gabriel M, Petersen N, Lintzel M, Behrens C, Eggert P, Pörtner K, Steiner J, Brönstrup M, Tappe D.   +13 more
europepmc   +4 more sources

Genome-wide profiling of long noncoding RNA expression patterns and CeRNA analysis in mouse cortical neurons infected with different strains of borna disease virus

Genes and Diseases, 2019
Borna disease virus 1 (BoDV-1) is neurotropic prototype of Bornaviruses causing neurological diseases and maintaining persistent infection in brain cells of mammalian species.
Lin Sun, Yujie Guo, Peng He, Xiaoyan Xu, Xiong Zhang, Haiyang Wang, Tian Tang, Wei Zhou, Ping Xu, Peng Xie   +9 more
doaj   +1 more source

Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study

Emerging Microbes and Infections, 2023
In 2018, Borna Disease Virus 1 (BoDV-1) was confirmed as a human zoonotic pathogen causing rare but fatal encephalitis in Germany. While diagnostic procedures and the clinical picture have been described, epidemiology remains mysterious.
Kirsten Pörtner, Hendrik Wilking, Christina Frank, Merle M. Böhmer, Klaus Stark, Dennis Tappe   +5 more
doaj   +1 more source