Results 81 to 90 of about 133,256 (260)

Revolutionizing nephrology research: expanding horizons with kidney-on-a-chip and beyond

open access: yesFrontiers in Bioengineering and Biotechnology
Organs-on-a-chip (OoC) is a microengineered three-dimensional cell culture system developed for decades. Utilizing microfluidic technology, OoC cultivates cells on perfusable channels to construct in vitro organ models, enabling the simulation of organ ...
Wei Huang   +3 more
doaj   +1 more source

One-step fabrication of an organ-on-a-chip with spatial heterogeneity using a 3D bioprinting technology [PDF]

open access: yes
Although various types of organs-on-chips have been introduced recently as tools for drug discovery, the current studies are limited in terms of fabrication methods.
Cho, DW, Lee, H
core   +1 more source

Alternative methods for regulatory toxicology – a state-of-the-art review [PDF]

open access: yes, 2014
This state-of-the art review is based on the final report of a project carried out by the European Commission’s Joint Research Centre (JRC) for the European Chemicals Agency (ECHA).
BREMER Susanne   +27 more
core   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Genome wide association study identifies novel candidate genes for growth and body conformation traits in goats

open access: yesScientific Reports, 2022
Pakistan is third largest country in term of goat population with distinct characteristics of breeds and estimated population of 78.2 million. Punjab province has 37% of country’s total population with seven important documented goat breeds namely Beetal,
Muhammad Moaeen-ud-Din   +2 more
doaj   +1 more source

Vascularization in organ- and body-on-a-chip platforms [PDF]

open access: yes, 2023
In tissue culture, soluble molecules such as gases, nutrients and waste are transported by diffusion. This limits the size of the tissue: if the dimensions of the tissue construct exceed the diffusion range, the inner parts of the tissue are deprived of ...
Kallio, Sanna
core  

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Artificial Intelligence‐based Online Symptom Assessment Tools for Systemic Lupus Erythematosus (SLE) diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this article is to identify perceptions of SLE patients regarding artificial intelligence (AI)‐based online symptom assessment tools, and the potential of these tools to address diagnostic barriers. Methods Adults from our SLE research cohort were invited to participate in 60‐90 minute virtual focus groups concerning their ...
Olivia A. Stein   +7 more
wiley   +1 more source

A return to normality: A descriptive qualitative interview study exploring the patient experience of gout flare resolution

open access: yesArthritis Care &Research, Accepted Article.
Objectives While the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semi‐structured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

Quantification of histone modification ChIP-seq enrichment for data mining and machine learning applications

open access: yesBMC Research Notes, 2011
Background The advent of ChIP-seq technology has made the investigation of epigenetic regulatory networks a computationally tractable problem. Several groups have applied statistical computing methods to ChIP-seq datasets to gain insight into the ...
Bekiranov Stefan   +2 more
doaj   +1 more source

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