Results 31 to 40 of about 5,537 (176)
Journal of Pharmacological Sciences, 2013 2-Arachidonoylglycerol (2-AG) is recognized as a potent endocannabinoid, which reduces synaptic transmission through cannabinoid CB1 receptors, and is hydrolyzed by monoacylglycerol lipase (MGL) to arachidonic acid (AA), a cyclooxygenase substrate.
Takahiro Shimizu +2 more
doaj +1 more source
IV. Effects of bombesin on behavior [PDF]
Life Sciences, 1985 This report describes the influence of bombesin on the gross behavior of goldfish, frogs, mice, rats, guinea pigs, rabbits, chicks, pigeons and monkeys. Goldfish, frogs, chicks and pigeons were overtly unaffected by bombesin given centrally and/or peripherally. Mice, rats, guinea pigs, rabbits and monkeys responded quickly to intracerebroventricular (i.
Cowan, Alan +3 more
openaire +3 more sources
Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells
Beilstein Journal of Nanotechnology, 2019 Background: Gastrin-releasing peptide is a member of the bombesin family of peptides. Its cognate receptor, gastrin releasing peptide receptor (GRPR), is widely expressed in cancers of the lung, pancreas and ovaries. Gastrin releasing peptide (GRP) is an
Mohammad J. Akbar +4 more
doaj +1 more source
Molecules, 2020 The organometallic technetium-99m tricarbonyl core, [99mTc][Tc(CO)3(H2O)3]+, is a versatile precursor for the development of radiotracers for single photon emission computed tomography (SPECT).
Carolina Giammei +9 more
doaj +1 more source
Effects of Bombesin and Bombesin-Like Peptides on Gastrointestinal Myoelectric Activity
Gastroenterology, 1975 Gastrointestinal myoelectric activity was studied during intravenous infusion of bombesin and bombesin-like peptides in conscious dogs with electrodes chronically implanted at different levels between the stomach and the rectum. The peptides used were bombesin, the COOH-terminal hepta- octa-, and nonapeptide of bombesin, and litorin, a new natural ...
CAPRILLI R. +4 more
openaire +4 more sources
A Bombesin-Shepherdin Radioconjugate Designed for Combined Extra- and Intracellular Targeting
Pharmaceuticals, 2014 Radiolabeled peptides which target tumor-specific membrane structures of cancer cells represent a promising class of targeted radiopharmaceuticals for the diagnosis and therapy of cancer.
Christiane A. Fischer +2 more
doaj +1 more source
Synthesis and Properties of Targeted Radioisotope Carriers Based on Poly(Acrylic Acid) Nanogels
Pharmaceutics, 2021 Radiation crosslinking was employed to obtain nanocarriers based on poly(acrylic acid)—PAA—for targeted delivery of radioactive isotopes. These nanocarriers are internally crosslinked hydrophilic macromolecules—nanogels—bearing carboxylic groups to ...
Małgorzata Matusiak +7 more
doaj +1 more source
Bombesin-Induced Gastroprotection
Annals of Surgery, 2005 Bombesin is an endogenous gut peptide that is prominent in the stomach. In addition to its effects on modulating acid and gut peptide secretion, recent evidence indicates that bombesin is a potent gastroprotective agent. This review article examines the ability of bombesin to prevent gastric injury.
Sonlee D, West, David W, Mercer
openaire +3 more sources
Neuropeptide G Protein-Coupled Receptors as Oncotargets
Frontiers in Endocrinology, 2018 Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they
Terry W. Moody +2 more
doaj +1 more source
Chemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi +6 more
wiley +1 more source