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YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulation in murine bone development. [PDF]
Collins JM +12 more
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Resistance training presents beneficial effects on bone development of adolescents engaged in swimming but not in impact sports: ABCD Growth Study. [PDF]
Agostinete RR +9 more
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Annual Review of Cell and Developmental Biology, 2000
▪ Abstract Early development of the vertebrate skeleton depends on genes that pattern the distribution and proliferation of cells from cranial neural crest, sclerotomes, and lateral plate mesoderm into mesenchymal condensations at sites of future skeletal elements.
B R, Olsen, A M, Reginato, W, Wang
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▪ Abstract Early development of the vertebrate skeleton depends on genes that pattern the distribution and proliferation of cells from cranial neural crest, sclerotomes, and lateral plate mesoderm into mesenchymal condensations at sites of future skeletal elements.
B R, Olsen, A M, Reginato, W, Wang
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Best Practice & Research Clinical Endocrinology & Metabolism, 2002
Puberty has a key role for bone development. Skeletal mass approximately doubles at the end of adolescence. The main determinants of pubertal gain of bone mass are the sex steroids, growth hormone and insulin-like growth factors (by their effects on bone and muscle mass), 1,25-dihydroxyvitamin D (by stimulating calcium absorption and retention) and ...
Giuseppe, Saggese +2 more
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Puberty has a key role for bone development. Skeletal mass approximately doubles at the end of adolescence. The main determinants of pubertal gain of bone mass are the sex steroids, growth hormone and insulin-like growth factors (by their effects on bone and muscle mass), 1,25-dihydroxyvitamin D (by stimulating calcium absorption and retention) and ...
Giuseppe, Saggese +2 more
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Current Opinion in Genetics & Development, 1998
A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor alpha 1 (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanism of bone formation--especially osteoblast differentiation.
T, Komori, T, Kishimoto
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A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor alpha 1 (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanism of bone formation--especially osteoblast differentiation.
T, Komori, T, Kishimoto
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Taurine, Bone Growth and Bone Development
Current Nutrition & Food Science, 2008Taurine (2-Amino ethane sulfonic acid) is a naturally occurring sulphur amino acid, found in several mammalian and non mammalian tissues. Taurine is believed to be involved in several life processes. Its deficiency is a cause of concern in developing abnormalities in many organs like eye, heart, kidney, brain etc during developmental stages and even ...
Sung-Jin Kim, Hyeon Lee, Ramesh Gupta
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BioEssays, 1987
AbstractAlthough bone development during embryogenesis and bone repair after injury have a number of features which appear similar, they are distinctly different processes which involve separate controlling elements and cuing parameters. Repair of bone is influenced by bioactive factors which reside in bone itself; some of these factors are not present
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AbstractAlthough bone development during embryogenesis and bone repair after injury have a number of features which appear similar, they are distinctly different processes which involve separate controlling elements and cuing parameters. Repair of bone is influenced by bioactive factors which reside in bone itself; some of these factors are not present
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Bone Structure, Development and Bone Biology
2009The skeleton serves as a structural support system. It has mechanisms to grow and change in shape and size to suit varying mechanical forces. It is involved in the calcium/phosphate balance and in the detoxification of heavy metals. Bone tissue is continuously formed and remodeled throughout life.
Jasvir S. Khurana, Fayez F. Safadi
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JAMA, 2010
Genetic and Epigenetic Aspects of Bone Development.- Tissue Interactions in Long Bone Development.- The Epiphyseal Growth Plate.- Hedgehog Signaling in Growth Plate and Bone Development.- Role of microRNA in Skeleton Development.- FGF/FGFR Signaling in Skeletal Dysplasias.- The Role of Hypoxia-Induced Factors.- BMP Signaling in Skeletogenesis.- Wnt ...
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Genetic and Epigenetic Aspects of Bone Development.- Tissue Interactions in Long Bone Development.- The Epiphyseal Growth Plate.- Hedgehog Signaling in Growth Plate and Bone Development.- Role of microRNA in Skeleton Development.- FGF/FGFR Signaling in Skeletal Dysplasias.- The Role of Hypoxia-Induced Factors.- BMP Signaling in Skeletogenesis.- Wnt ...
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Proteoglycans on bone tumor development
Drug Discovery Today, 2010Proteoglycans, extracellular matrix components, exert several activities on bone cells and seem crucial for maintaining an appropriate number of osteoblasts and osteoclasts. The overall data strengthen a pro-bone resorptive role for proteoglycans, through the control of osteoprotegerin availability and of receptor activator of NF-kappaB ligand ...
Carmen Ruiz, Velasco +4 more
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