Results 261 to 270 of about 1,973,327 (305)

Bone development in neurofibromatosis 1

Medical Hypotheses, 2003
Bony abnormalities are common findings in cases of neurofibromatosis 1. We might hypothesize that neurofibromin, the protein encoded by the neurofibromatosis 1 gene, plays important roles in bone development. Loss of function of oligodendrocyte-myelin glycoprotein gene and increased activity of ras p21 might increase the level of c-fos proto-oncogene ...
M E, Abdel-Wanis, N, Kawahara
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Bone Development: Overview of Bone Cells and Signaling

Current Osteoporosis Reports, 2011
Vertebrates evolved elaborating a structure made up of more than 200 bones and cartilages articulated with one another to form the skeleton, through which locomotion, organ protection, lodging of hematopoiesis, and mineral homeostasis are allowed. Skeletogenesis starts at the fetal stage, along with marrow hematopoiesis, and evolves postnatally through
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Growth factors influencing bone development

Journal of Cell Science, 1990
ABSTRACT We have approached the study of growth factors affecting cartilage and bone development by investigating those factors present in bone which are able to initiate new cartilage and bone formation in vivo. This has led to the identification and molecular cloning of seven novel human factors which we have named BMP-1 through BMP-7.
J M, Wozney, V, Rosen, M, Byrne, A J, Celeste, I, Moutsatsos, E A, Wang   +5 more
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Bone development in Japanese quail

The Anatomical Record, 1963
AbstractThe development of the long bones of Japanese Quail was studied histologically and microradiographically at different post‐hatching periods from birth to one year of age. At the level of the mid‐shaft, the woven bone of the neonatal animal becomes thicker by rapid periosteal growth and becomes consolidated by the deposition of bone within large
D J, SIMMONS, A M, PANKOVICH
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Benign bone tumors—recent developments

Seminars in Diagnostic Pathology, 2011
Benign bone tumors frequently pose a diagnostic challenge for general surgical pathologists. Accurate pathologic diagnosis requires careful clinical and radiological correlation. The most significant recent advances in some benign bone tumors have occurred at the molecular and cytogenetic level.
Roberto A, Garcia, Carrie Y, Inwards, Krishnan K, Unni   +2 more
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Bone development.

Ciba Foundation symposium, 1989
The sequential cellular and molecular details of the initial embryonic formation of bone can be used to gain insight into the control of this process and subsequent bone physiology and repair. The functioning of osteogenic cells is governed by a complex balance between the intrinsic capacities of these cells in the context of extrinsic information and ...
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New developments in bone formation

Current Opinion in Nephrology and Hypertension, 1998
Two independent strategies have established that the transcription factor, Cbfa1, is a key regulator of both osteoblast differentiation and osteoblast-specific gene expression. Gene targeting experiments in mice have also shown that haploinsufficiency of Cbfa1 expression causes symptoms reminiscent of the Cleidocranial dysplasia syndrome (CCD), a ...
M J, Owen, G, Karsenty
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Microinterferometry of developing bone mineral

Calcified Tissue Research, 1974
A method based on tetracycline labeling was developed for selecting, in frozen sections of fetal mouse femur, bone foci approximately 6, 24, 48 and 72 h of age. Microinterferometric measurements of these foci permitted a calculation of the effective thickness (t) and refractive index (n) of each focus.
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Bone morphogenetic proteins in development

Current Opinion in Genetics & Development, 1996
The bone morphogenetic proteins (BMPs) constitute a large family of cytokines related to members of the transforming growth factor-beta superfamily. Recent evidence, in particular from gene targeting experiments in the mouse, indicates that BMPs are required for mesoderm formation and for the development and patterning of many different organ systems ...
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Immunologic Regulation of Bone Development

2007
A regulatory network comprised of transcription factors PU.1, Ikaros, E2A, EBF, and Pax5 control B cell fate specification and differentiation. Early B Cell Factor-1 (EBF-1) is essential for B cell fate specification while Pax5 is required for B cell development.
Mark C, Horowitz, Joseph A, Lorenzo
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