Results 1 to 10 of about 696,905 (338)

Effects of erythropoietin on osteoblast in the tooth extraction socket in mice periodontitis model

open access: yesFrontiers in Physiology, 2022
Periodontitis is an excessive inflammatory event in tooth-supporting tissues and can cause tooth loss. We used erythropoietin (EPO), which has been reported to play an important role in bone healing and modulation of angiogenesis, as a therapeutic agent ...
Ju-Eun Bae   +13 more
doaj   +1 more source

A mechanistic review of chinese medicine polyphenols on bone formation and resorption

open access: yesFrontiers in Pharmacology, 2022
Bone reconstruction includes a steady state system of bone formation and bone absorption. This tight coupling requires subtle coordination between osteoblasts and osteoclasts.
Yan Li   +20 more
doaj   +1 more source

The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry

open access: yeseLife, 2021
Background: Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis.
Melanie Castro-Mollo   +18 more
doaj   +1 more source

Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants

open access: yesBone & Joint Research, 2022
Aims: To develop an early implant instability murine model and explore the use of intermittent parathyroid hormone (iPTH) treatment for initially unstable implants.
Kevin Staats   +10 more
doaj   +1 more source

The Role of Intestinal Flora in the Regulation of Bone Homeostasis

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Intestinal flora located within the intestinal tract comprises a large number of cells, which are referred to as the second gene pool of the human body and form a complex symbiotic relationship with the host.
Chengxiang Li, Guofu Pi, Feng Li
doaj   +1 more source

Theaflavin-3,3′-Digallate Promotes the Formation of Osteoblasts Under Inflammatory Environment and Increases the Bone Mass of Ovariectomized Mice

open access: yesFrontiers in Pharmacology, 2021
Postmenopausal osteoporosis is a disease of bone mass reduction and structural changes due to estrogen deficiency, which can eventually lead to increased pain and fracture risk. Chronic inflammatory microenvironment leading to the decreased activation of
Gaoran Ge   +10 more
doaj   +1 more source

Muscle-Derived Lumican Stimulates Bone Formation via Integrin α2β1 and the Downstream ERK Signal

open access: yesFrontiers in Cell and Developmental Biology, 2020
Skeletal muscle and bone are highly interrelated, and previous proteomic analyses suggest that lumican is one of muscle-derived factors. To further understand the role of lumican as a myokine affecting adjacent bone metabolism, we investigated the ...
Jin Young Lee   +5 more
doaj   +1 more source

Long-term Consequences of Traumatic Brain Injury in Bone Metabolism

open access: yesFrontiers in Neurology, 2018
Traumatic brain injury (TBI) leads to long-term cognitive, behavioral, affective deficits, and increase neurodegenerative diseases. It is only in recent years that there is growing awareness that TBI even in its milder form poses long-term health ...
Nikita M. Bajwa   +5 more
doaj   +1 more source

Effects of systemically administered abaloparatide, an osteoanabolic PTHrP analog, as an adjuvant therapy for spinal fusion in rats

open access: yesJOR Spine, 2021
Background Abaloparatide is a parathyroid hormone receptor agonist that increases bone formation and reduces vertebral and nonvertebral fracture risk in women with postmenopausal osteoporosis.
Heike Arlt   +4 more
doaj   +1 more source

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