Bone augmentation by replica-based bone formation [PDF]
Dental Materials, 2020 The sources of iliac crest bone grafts are limited. Alternatives are evaluated due to the progress in biomaterial sciences. Synthetical hydroxyapatite (HA), ß-tricalcium phosphate (ß-TCP) or biphasic compounds, or even a mélange of HA and ß-TCP will replace bovine ceramics.
M.E. Draenert +4 more
openaire +3 more sources
The Role of Osteocytes in Targeted Bone Remodeling: A Mathematical Model [PDF]
, 2013 Until recently many studies of bone remodeling at the cellular level have focused on the behavior of mature osteoblasts and osteoclasts, and their respective precursor cells, with the role of osteocytes and bone lining cells left largely unexplored. This
Ayati, Bruce P. +3 more
core +11 more sources
Exenatide Improves Bone Quality in a Murine Model of Genetically Inherited Type 2 Diabetes Mellitus [PDF]
, 2017 Type 2 diabetes mellitus (T2DM) is associated with skeletal complications, including an increased risk of fractures. Reduced blood supply and bone strength may contribute to this skeletal fragility.
Andreozzi +64 more
core +6 more sources
Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]
, 2008 Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J. +6 more
core +1 more source
Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth [PDF]
, 2017 Bone morphogenetic proteins (Bmp) are well-known to induce bone formation following chondrogenesis, but the direct role of Bmp signaling in the osteoblast lineage is not completely understood.
Bellido, Teresita +5 more
core +3 more sources
lncRNA MEG3 Suppresses the Progression of Ankylosis Spondylitis by Regulating the Let-7i/SOST Axis
Frontiers in Molecular Biosciences, 2020 Ankylosis spondylitis (AS) is a disease mainly characterized by sacroiliac joint and spinal attachment point inflammation. Long non-coding RNA (lncRNA) plays a key role in the progression of many diseases.
Junjie Ma +3 more
doaj +1 more source
JOR Spine, 2021 Background Abaloparatide is a parathyroid hormone receptor agonist that increases bone formation and reduces vertebral and nonvertebral fracture risk in women with postmenopausal osteoporosis.
Heike Arlt +4 more
doaj +1 more source
Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2. [PDF]
, 2017 Although bone morphogenetic protein-2 (BMP2) has demonstrated extraordinary potential in bone formation, its clinical applications require supraphysiological milligram-level doses that increase postoperative inflammation and inappropriate adipogenesis ...
Aghaloo, Tara L +8 more
core +1 more source
p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. [PDF]
, 2017 Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts.
Ao, Junping +9 more
core +1 more source
Nobiletin, a NF‐κB signaling antagonist, promotes BMP‐induced bone formation
FASEB BioAdvances, 2023 The NF‐κB family of transcription factors plays an important role in skeletal development and bone homeostasis. In osteoblast cells, NF‐κB signaling has been shown to suppress survival, proliferation, and differentiation.
Thira Rojasawasthien +7 more
doaj +1 more source