VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo [PDF]
European Cells & Materials, 2010 Bone formation and osseointegration of biomaterials are dependent on angiogenesis and vascularization. Angiogenic growth factors such as vascular endothelial growth factor (VEGF) were shown to promote biomaterial vascularization and enhance bone ...
E Wernike +7 more
doaj
The Role of Intestinal Flora in the Regulation of Bone Homeostasis
Frontiers in Cellular and Infection Microbiology, 2021 Intestinal flora located within the intestinal tract comprises a large number of cells, which are referred to as the second gene pool of the human body and form a complex symbiotic relationship with the host.
Chengxiang Li, Guofu Pi, Feng Li
doaj +1 more source
Frontiers in ImmunologyIt is well established that inflammatory processes in the vicinity of bone often induce osteoclast formation and bone resorption. Effects of inflammatory processes on bone formation are less studied.
Petra Henning +15 more
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Osteocytes as a record of bone formation dynamics: A mathematical model of osteocyte generation in bone matrix [PDF]
, 2014 The formation of new bone involves both the deposition of bone matrix, and the formation of a network of cells embedded within the bone matrix, called osteocytes.
Buenzli, Pascal R
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Heterotopic intrauterine bone formation
Journal of Obstetrics and Gynaecology, 2007 A 24-year-old Caucasian female was referred by her GP to the gynaecology outpatient clinic complaining of worsening pelvic pain over the past year.
L S, Louis +2 more
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Pathogenesis of thoracic ossification of the ligamentum flavum
Frontiers in PharmacologyThoracic ossification of the ligamentum flavum (TOLF) is characterized by ectopic ossification of the ligamentum flavum in the thoracic spine and is considered the main cause of thoracic spinal stenosis and spinal cord disease.
Chi Zhang +5 more
doaj +1 more source
Frontiers in Endocrinology, 2020 Immobilization results in a substantial bone loss and increased fracture risk. Powerful bone anabolic therapies are necessary to counteract the bone loss and reduce fracture risk during periods with immobilization.
Mikkel Bo Brent +2 more
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Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity [PDF]
, 2017 Extracellular signal-regulated protein kinase 5 (ERK5) has been implicated during development and carcinogenesis. Nkx3.1-mediated Cre expression is a useful strategy to genetically manipulate the mouse prostate. While grossly normal at birth, we observed
Ahmad, Imran +15 more
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Effects of erythropoietin on osteoblast in the tooth extraction socket in mice periodontitis model
Frontiers in Physiology, 2022 Periodontitis is an excessive inflammatory event in tooth-supporting tissues and can cause tooth loss. We used erythropoietin (EPO), which has been reported to play an important role in bone healing and modulation of angiogenesis, as a therapeutic agent ...
Ju-Eun Bae +13 more
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Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists. [PDF]
, 2016 UnlabelledAlthough adipose-derived stem cells (ASCs) are an attractive cell source for bone tissue engineering, direct use of ASCs alone has had limited success in the treatment of large bone defects.
Aghaloo, Tara L +11 more
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