Results 41 to 50 of about 7,909,245 (408)

THE EFFECT OF SURFACE TREATMENT OF THE DENTAL IMPLANT ON THE SEOINTEGRATION IN MANDIBULAR POSTERIOR MISSING TEETH: A RANDOMIZED CONTROLLED CLINICAL TRIAL [PDF]

Alexandria Dental Journal, 2023
Introduction: Dental implants have lately emerged as a viable therapeutic option for replacing missing teeth. Implants have undergone continuous improvement to increase their functionality and longevity to meet patients' needs for shorter treatment ...
Marwa Mohamed, Riham Fliefel, Ahmed Shaaban   +2 more
doaj   +1 more source

The mechanosensitive Piezo1 channel is required for bone formation

eLife, 2019
Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that
Weijia Sun, Shaopeng Chi, Yuheng Li, S. Ling, Yingjun Tan, Youjia Xu, Fan Jiang, Jianwei Li, Caizhi Liu, Guohui Zhong, Dengchao Cao, Xiaoyan Jin, Dingsheng Zhao, Xingcheng Gao, Zizhong Liu, Bailong Xiao, Yingxian Li   +16 more
semanticscholar   +1 more source

Muscle-Derived Lumican Stimulates Bone Formation via Integrin α2β1 and the Downstream ERK Signal

Frontiers in Cell and Developmental Biology, 2020
Skeletal muscle and bone are highly interrelated, and previous proteomic analyses suggest that lumican is one of muscle-derived factors. To further understand the role of lumican as a myokine affecting adjacent bone metabolism, we investigated the ...
Jin Young Lee, So Jeong Park, Da Ae Kim, Seung Hun Lee, Jung-Min Koh, Beom-Jun Kim   +5 more
doaj   +1 more source

Theaflavin-3,3′-Digallate Promotes the Formation of Osteoblasts Under Inflammatory Environment and Increases the Bone Mass of Ovariectomized Mice

Frontiers in Pharmacology, 2021
Postmenopausal osteoporosis is a disease of bone mass reduction and structural changes due to estrogen deficiency, which can eventually lead to increased pain and fracture risk. Chronic inflammatory microenvironment leading to the decreased activation of
Gaoran Ge, Sen Yang, Zhenyang Hou, Minfeng Gan, Huaqiang Tao, Wei Zhang, Wenming Li, Zheng Wang, Yuefeng Hao, Ye Gu, Dechun Geng   +10 more
doaj   +1 more source

VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo [PDF]

European Cells & Materials, 2010
Bone formation and osseointegration of biomaterials are dependent on angiogenesis and vascularization. Angiogenic growth factors such as vascular endothelial growth factor (VEGF) were shown to promote biomaterial vascularization and enhance bone ...
E Wernike, M-O Montjovent, Y Liu, D Wismeijer, EB Hunziker, K-A Siebenrock, W Hofstetter, FM Klenke   +7 more
doaj  

The Role of Intestinal Flora in the Regulation of Bone Homeostasis

Frontiers in Cellular and Infection Microbiology, 2021
Intestinal flora located within the intestinal tract comprises a large number of cells, which are referred to as the second gene pool of the human body and form a complex symbiotic relationship with the host.
Chengxiang Li, Guofu Pi, Feng Li
doaj   +1 more source

Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

Cell Discovery
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo differentiation into osteoblasts. This differentiation process plays a crucial role in bone formation and homeostasis and is regulated by two intricate processes: cell ...
Siyu Zhu, Wei Chen, Alasdair Masson, Yi-Ping Li   +3 more
semanticscholar   +1 more source

Gli1 identifies osteogenic progenitors for bone formation and fracture repair

Nature Communications, 2017
Bone formation in mammals requires continuous production of osteoblasts throughout life. A common molecular marker for all osteogenic mesenchymal progenitors has not been identified.
Yu Shi, Guangxu He, Wen-Chih Lee, J. McKenzie, Matthew J. Silva, Fanxin Long   +5 more
semanticscholar   +1 more source

Toll-like receptor-2 induced inflammation causes local bone formation and activates canonical Wnt signaling

Frontiers in Immunology
It is well established that inflammatory processes in the vicinity of bone often induce osteoclast formation and bone resorption. Effects of inflammatory processes on bone formation are less studied.
Petra Henning, Ali Kassem, Anna Westerlund, Pernilla Lundberg, Cecilia Engdahl, Cecilia Engdahl, Vikte Lionikaite, Pernilla Wikström, Jianyao Wu, Lei Li, Catharina Lindholm, Catharina Lindholm, Pedro P. C. de Souza, Sofia Movérare-Skrtic, Ulf H. Lerner, Ulf H. Lerner   +15 more
doaj   +1 more source

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

Bone Research
Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface to activate canonical or non-canonical Wnt signaling pathways, which control various biological processes throughout embryonic development and adult life ...
Lifang Hu, Wei Chen, Airong Qian, Yi-Ping Li   +3 more
semanticscholar   +1 more source