Results 91 to 100 of about 1,355,503 (353)

The induction of bone formation by 3D-printed PLGA microsphere scaffolds in a calvarial orthotopic mouse model: a pilot study

Frontiers in Bioengineering and Biotechnology
Polymeric biodegradable microspheres are readily utilized to support targeted drug delivery for various diseases clinically. 3D printed tissue engineering scaffolds from polymer filaments with embedded microspheres or nanoparticles, as well as bulk ...
Roland M. Klar, James C. Cox, Claire J. Houchen, Naren Raja, Houssam Bouloussa, Stefan Lohfeld   +5 more
doaj   +1 more source

Osteoblasts and bone formation.

Acta reumatologica portuguesa, 2007
© 2007 Sociedade Portuguesa de ...
Caetano-Lopes, Joana, Canhao, Helena, Fonseca, João Eurico   +2 more
openaire   +2 more sources

Synthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic application [PDF]

, 2016
The composite materials based on hydroxyapatite (HA) and gelatine (Gel) with addition of silver and zirconium oxide were obtained. The study investigates a combination of low powered ultrasonic irradiation and low concentration of gelatine in the co ...
Bolshanina, S., Danilchenko, S., Husak, Е., Kuznetsov, V., Pogorielov, М., Stanislavov, A., Starikov, V., Yanovska, А.   +7 more
core  

Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α2β1 Signaling. [PDF]

, 2016
Unlabelled: The induction of mesenchymal stem cells (MSCs) toward the osteoblastic lineage using osteogenic supplements prior to implantation is one approach under examination to enhance their bone-forming potential.
Harvestine, Jenna N, Hoch, Allison I, Leach, J Kent, Murphy, Kaitlin C, Zhou, Dejie   +4 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Efficacy of 3D-Printed Scaffolds in Guided Tissue Regeneration for Combined Endo-Perio Lesions: A Clinical and Radiographic Study

Journal of Pharmacy and Bioallied Sciences
Background: Combined endo-perio lesions (CEPLs) are one of the toughest problems in clinical dentistry because of complex causative factors and multi-rooted anatomical structures.
Anuj Singh Parihar, Nimisha Nandanan, Hiren H. Patadiya, Meetu Jain, Aishwarya Arya, Rashmi Laddha, Santosh Kumar   +6 more
doaj   +1 more source

Histomorphometric evaluation of bone regeneration induced by biodegradable scaffolds as carriers for dental pulp stem cells in a rat model of calvarial "critical size" defect [PDF]

, 2016
Objective: The aim of this study was to test specific stem cells that could enhance bone formation in combination with specific scaffolds. Methods: Dental Pulp Stem Cells (DPSCs) were seeded with Granular Deproteinized Bovine Bone (GDPB) or Beta ...
ANNIBALI, Susanna, BELLAVIA, Diana, CICCONETTI, Andrea, CRISTALLI, MARIA PAOLA, OTTOLENGHI, Livia, PILLONI, ANDREA, QUARANTA, ROBERTA, Scarano, Antonio   +7 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Tensile Stress‐Activated and Exosome‐Transferred YAP/TAZ‐Notch Circuit Specifies Type H Endothelial Cell for Segmental Bone Regeneration

Advanced Science
The Ilizarov technique has been continuously innovated to utilize tensile stress (TS) for inducing a bone development‐like regenerative process, aiming to achieve skeletal elongation and reconstruction.
Feng Wang, Shanyu Li, Lingchi Kong, Kai Feng, Rongtai Zuo, Hanzhe Zhang, Yifan Yu, Kunqi Zhang, Yuting Cao, Yimin Chai, Qinglin Kang, Jia Xu   +11 more
doaj   +1 more source